Stanford Cryo-Electron Microscopy Center (CEMC)

   

Documentation Website

Visit our Documentation Website for more information useful to Stanford CEMC users.

Stanford CEMC enables nanoscale visualization of biological and inorganic material, providing key insights into protein and cellular function and material science. We provide training, data acquisition, data interpretation, and sample preparation for cryogenic electron microscopy (cryo-EM), cryogenic electron tomography (cryo-ET), and focused ion beam milling scanning electron microscopy (cryo-FIB-SEM). Our resources foster cutting-edge research into scientific questions such as: What is the impact of a mutation on organelle morphology? Where does a drug bind to a target? How can we probe the function of this receptor? How does material morphology change in response to a stimulus?

 

We provide an open and collaborative environment supporting the Stanford community as well as external academic and industry projects. Explore our resources, and contact us to see how CEMC can empower your science!

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Updates

 

Visit the Updates page of our Documentation website to see all our updates.

What We Offer

 

CEMC provides equipment and expertise for researchers to access cryo-EM and related techniques. Our services include:

  • FIB milling of biological samples
  • High-resolution data collection for single-particle analysis (SPA), tomography, and soft-matter research
  • High-throughput cryo sample screening and collection of diagnostic small data sets
  • Negative Stain electron microscopy
  • Training and various levels of assistance for diverse experimental designs, including sample preparation, negative stain screening, and equipment operation
  • Full-service option for screening and data collection—we do it for you!

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Who We Serve

 

Our primary mission is to empower the Stanford research community to accelerate discovery through open access to cutting-edge cryo-EM services.

We also provide services to any university, consortium, or other nonprofit research organization that seeks to apply cryo-EM technologies. Contact us to learn more!

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Contact Us

 

Contact us to discuss how cryo-EM can support your research