2021
Tue - Wed
Day 1- Opening Remarks
Day 1- Keynote
Day 1- Session 1
Day 1- Session 2
Day 1- Session 3
Day 2- Keynote
Day 2 - Session 4
Day 2- Session 5
International Symposium on αβ T-Cell/CD19 B-Cell Depleted Haploidentical HSCT
First International Symposium on αβ T-Cell/CD19 B-Cell Depleted Haploidentical HSCT
This scientific conference will bring together for the first-time clinicians, basic scientists, and translational investigators to discuss new advances in the field of αβ T-cell/CD19 B-cell depleted haploidentical stem cell transplantation for children and adults.
This is a free virtual symposium. All are welcome to participate. Registration is now open!
PROGRAM
8:00-8:10am |
Opening Remarks: Alice Bertaina, MD, PhD, Associate Professor; Section Chief, Pediatric Hematology, Oncology, Stem Cell Transplantation & Regenerative Medicine and Medical Director of Inpatient Services; Co-Director Bass Center for Childhood Cancer and Blood Diseases, Stanford University |
8:10-8:20am |
Welcome: Lloyd Minor, Dean, School of Medicine, Stanford University and Paul A. King, President and CEO, Lucile Packard Children's Hospital |
Opening Keynote |
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8:20-9:10am
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Introduction of Keynote: Robertson Parkman, MD, Adjunct Professor of Pediatrics,Pediatric Hematology, Oncology, Stem Cell Transplantation & Regenerative Medicine, Stanford University Keynote: Yair Reizner, MD, PhD, Professor, Department of Stem Cell Transplantation, Division of Cancer Medicine, The University of Texas, MD Anderson Cancer Center Title: The History of T-cell Depleted Haploidentical HSCT |
Session 1: Adaptive versus Innate Immunity in ab T-cell/CD19 B-cell Depleted Haploidentical HSCT: which one matters? Moderator: Leslie S. Kean, MD, PhD, Director, Stem Cell Transplant Center, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School |
9:10-9:40am |
Jürgen Kuball, PhD, Professor, UMC Utrecht Cancer Center, UMC Utrecht, Netherlands Title: The Biology of gd T cells: Is this the secret for the success? |
9:40-10:10am |
Alice Bertaina, MD, PhD, Associate Professor, Stanford University Title: ab T-cell/CD19 B-cell Depleted Haploidentical HSCT: A Platform for Immunotherapy |
10:10-10:20am |
Q&A and Session Discussion |
10:20-11:00am |
BREAK |
Session 2: The Importance of Immune Reconstitution
Moderator: Jaap-Jan Boelens, MD, PhD, Chief, Pediatric Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York
11:00-11:30am |
Susan E. Prockop, MD, Head, Clinical Research Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center Title: Immune Reconstitution After T-cell Depleted Haploidentical HSCT |
11:30-12:00pm |
Andrew Gennery, MD, Professor in Pediatric Immunology and HSCT, Institute of Translational and Clinical Research, Pediatric Immunology Dept., Great North Children's Hospital, Newcastle University, UK Title: ab T-cell/CD19 B-cell Depleted Haploidentical HSCT in PIDs: The UK Experience
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12:00-12:30pm |
Michael Maschan, Department Lead, Department of Hematopoietic Stem Cell Transplantation, Dmitriy Rogachev National Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russia Title: Viral Infections After ab T-cell/CD19 B-cell Depleted Haploidentical HSCT: The Role of CD45RA+ Depleted DLI |
12:30-12:45pm |
Q&A and Session Discussion |
12:45-1:30pm |
BREAK |
Session 3: T-cell depleted haploidentical HSCT in adults
Moderator: Everett Meyer, MD, PhD, Assistant Professor of Medicine, Blood and Marrow Transplantation and Cellular Therapy, Stanford University
1:30-2:00pm |
Wolfgang Bethge, MD, Associate Professor, Hematology and Oncology Hematopoietic Stem Cell Transplantation, University of Tübingen, Germany Title: ab T-cell/CD19 B-cell Depleted Haploidentical HSCT in Adults |
2:00-2:30pm |
Robert Lowsky, MD, Professor of Medicine, Blood and Marrow Transplantation and Cellular Therapy, Stanford University Title: New Approaches to Boost GvL after T-cell Depleted Haploidentical HSCT: The Experience of the Stanford Adult BMT Group |
2:30-2:45 pm 2:45-3:00pm |
Q&A and Session Discussion Conclusions of the day – Alice Bertaina, MD, PhD, Stanford University |
Day 2: |
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7:20-7:30am |
Welcome Introduction: Maria Grazia Roncarolo, MD, George D. Smith Professor in Stem Cell and Regenerative Medicine; Professor of Pediatrics and Medicine, Director of the Center for Definitive and Curative Medicine, and Co-Director of the Institute for Stem Cell Biology and Regenerative Medicine, Stanford University |
Session 4: Is ab T-cell/CD19 B-cell Depletion the Best Platform for haploidentical HSCT? Let’s debate Moderator: Michael Pulsipher, MD, Section Head, Transplantation and Cellular Therapy, BMT Clinical Research, Hematology, Oncology and Blood and Marrow Transplantation; Professor of Clinical Pediatrics, Keck School of Medicine of University of Southern California |
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7:30-8:00am |
Franco Locatelli, MD, Full Professor of Pediatrics, Sapienza University of Rome; Director, Department of Pediatric Hematology and Oncology, IRCCS Ospedale Bambino, Rome, Italy Title: ab T-cell/CD19 B-cell Depleted Haploidentical HSCT |
8:00-8:30am |
Brandon Triplett, MD, Associate Member, St. Jude Faculty; Chief, Bone Marrow Transplant Clinical Service, Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital Title: CD45RA+ Depleted Haploidentical HSCT |
8:30-9:00am |
Kenneth Cooke, MD, Herman and Walter Samuelson Professor, Director, Pediatric Bone Marrow Transplantation Program, Johns Hopkins Kimmel Cancer Center Title: Haploidentical HSCT with PT-Cy |
9:00-9:15am |
Q&A and Session Discussion |
9:15-10:00am |
BREAK |
Session 5: Innovative Pilot Clinical Trials
Moderator: Maria Grazia Roncarolo, MD, George D. Smith Professor in Stem Cell and Regenerative Medicine, Professor of Pediatrics and Medicine; Director of the Center for Definitive and Curative Medicine, and Co-Director of the Institute for Stem Cell Biology and Regenerative Medicine, Stanford University
10:00-10:20am |
Agnieszka Czechowitz, MD, PhD, Assistant Professor, Pediatric Hematology, Oncology, Stem Cell Transplantation & Regenerative Medicine, Stanford University Title: ab T-cell/CD19 B-cell Depleted Haploidentical HSCT Combined with Antibody Conditioning Regimen for Fanconi Anemia |
10:20-10:40am |
Joseph Oved, MD, MA, Attending Physician, Division of Hematology, Children's Hospital of Philadelphia Title: ab T-cell/CD19 B-cell Depleted Mismatched HSCT for Severe Aplastic Anemia |
10:40-11:00am |
Alice Bertaina, MD, PhD, Associate Professor, Stanford University Title: ab T-cell/CD19 B-cell Depleted Haploidentical HSCT and Solid Organ Transplant to Promote Functional Immune Tolerance |
11:00-11:20am |
Christopher Dvorak, MD, Chief, Division of Pediatric Allergy, Immunology and Bone Marrow Transplantation; Medical Director, Pediatric Cellular Therapy Laboratory, UCSF Benioff Children's Hospital, UCSF Title: Non TBI-based Conditioning for Acute Lymphoblastic Leukemia NGS MRD Negative |
11:20-11:40am
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Matthew Porteus, MD, PhD, Sutardja Chuk Professor of Definitive and Curative Medicine; Professor of Pediatrics, Pediatric Hematology, Oncology, Stem Cell Transplantation & Regenerative Medicine; Co-Director, Center for Definitive and Curative Medicine, Stanford University Title: ab T-cell/CD19 B-cell Depleted Haploidentical HSCT and CAR T Cells |
11:45-12:00pm |
Q&A and Session Discussion |
Closing Keynote: |
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12:00-12:50pm |
Introduction of Closing Lecture: Tanja Gruber, MD, PhD, Endowed Professor for Pediatric Cancer; Division Chief, Pediatric Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Stanford University; Director, Bass Center for Childhood Cancer and Blood Diseases, Stanford University Closing Lecture: Rupert Handgretinger, MD, PhD, Professor of Pediatrics; Chairman, Department of General Pediatrics and Hematology/Oncology, Children’s University Hospital, Tübingen, Germany Title: The Future of T-cell Depleted HSCT |
12:50-1:00pm |
Closing Remarks: Alice Bertaina, MD, PhD, Stanford University |
WEBINAR DETAILS FOR OCT 19th and OCT 20th:
Please click the link below to join the webinar for both days: October 19th and October 20th.
https://stanford.zoom.us/j/93135942971?pwd=cWxmblNjd1hqem0raCtmdVZQblI2QT09
Passcode: 672994
Or One tap mobile :
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Or Telephone:
Dial(for higher quality, dial a number based on your current location):
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Webinar ID: 931 3594 2971
Passcode: 672994
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H.323:
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Meeting ID: 931 3594 2971
Passcode: 672994
Passcode: 672994