February 25 Feb 25
2021
Thursday Thu
Event

CDCM 5th Annual Symposium

Save the Date: 2/25/21

Learn about new cell, gene, and regenerative medicine discoveries, pre-clinical development and clinical trials of curative medicines and challenges in bringing these cures to market at this one-day conference for clinicians, basic scientists, patient advocates, translational investigators and biotech and pharmaceutical experts.

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Program

5th Annual Center for Definitive and Curative Medicine (CDCM)

Symposium Program

Thursday, February 25, 2021 (8:30-3:00)

8:30-8:35

Open Zoom-Waiting Room

8:35-8:55

Opening remarks:    Lloyd Minor, MD, Dean, School of Medicine, Stanford University 

 

David Entwistle, President and CEO, Stanford Health Care

 

Paul King, President and CEO, Stanford Children’s Health 

 

Irv Weissman, MD, Director, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University

8:55-9:00

Maria Grazia Roncarolo, MD, Director, CDCM, Stanford University

Opening Keynote:

9:00-9:45

Introduction of KeynoteAnthony Oro, MD, PhD, Co-Director, CDCM, Stanford University

Keynote: Deepak Srivastava, MD, President, Gladstone Institutes, Director, Roddenberry Stem Cell Center at Gladstone and Professor, University of California San Francisco

Title: “Cellular Reprogramming Approaches for Human Disease”

Session 1

9:50-10:15

Vittorio Sebastiano, PhD, Assistant Professor Obstetrics and Gynecology, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University

Title: “Epigenetic Reprogramming of Aging: Curative Implications for the Elderly”

10:15-10:40

Kristy Red-Horse, PhD, Associate Professor of Biology, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University

Title: "Comparing Coronary Artery Development in Mouse and Human"

10:40-10:55

Break

Session 2

10:55-11:20

Michael A. Fischbach, PhD, Associate Professor, Department of Bioengineering and Medicine, Stanford University

Title: "Small Molecules from the Human Microbiota"

11:20-11:45

Hiro Nakauchi, MD, PhD, Professor of Genetics, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University

Title: “Ex vivo expansion of HSCs: towards a holy grail in hematology”

 

11:50-12:30

 

LUNCH BREAK: “Talk to the CDCM Experts” 

Rosa Bacchetta- “Why gene therapy for IPEX syndrome to treat autoimmunity?”

Zoom: https://stanford.zoom.us/j/91035583486?pwd=OFpIMXMzZXI2ZEUzeG5ia3psQk9mUT09

Meeting ID: 910 3558 3486; Password: 644863

Natalia Gomez-Ospina- “Hematopoietic Stem Cell Transplantation of Genome-edited Cells for Neurological Diseases”

Zoom:https://stanford.zoom.us/j/97733099494?pwd=UGZ0dFAxUVQ2SUJYK3NDamNva2IxZz09

Meeting ID: 977 3309 9494; Password: 091532

Bertha Chen“Challenges with Translation of Mesenchymal Cell Therapies”

Zoom:  https://stanford.zoom.us/j/97954263456?pwd=bGgySDJGbE52ZG90M1dMUXFLTkh6Zz09

Meeting ID: 979 5426 3456; Password: 522609

Agnieszka CzechowiczProgress Towards Safe, Curative Treatment of Blood and Immune Diseases: Development of Novel Conditioning Regimens for Hematopoietic Cell Transplantation”

Zoom: https://stanford.zoom.us/j/94780142033?pwd=MFVsSExJMkpBdllmVFdIeW13aXhqdz09

Meeting ID: 947 8014 2033; Password: 513488

Alice Bertaina“Graft Engineering for Treating Malignant and Non-Malignant Disorders”

Zoom:  https://stanford.zoom.us/j/99381283362?pwd=WG9hQk5adHVyRnJ6U0ViT3AzTDlOdz09

Meeting ID: 993 8128 3362; Password: 731869

Fraser Wright“AAV Gene Therapy Vectors – Optimizing Design to Address Immune Barriers”

Zoom https://stanford.zoom.us/j/93032416638?pwd=Y1Mxd01HMXdhMGh5T3ZnT2dTbE5Ddz09

Meeting ID: 930 3241 6638; Password: 251000

Neehar Bhatia- “cGMP Manufacturing of Cell and Gene Therapies: Overcoming the Challenges”

Zoom:  https://stanford.zoom.us/j/96995790368?pwd=VHJ4NDBPZkY2a3c0d2wrTVhLZFJMZz09

Meeting ID: 969 9579 0368; Password: 571006

Keynote:

12:30-1:15

Introduction of KeynoteMaria T. Millan, MD, President and CEO, California Institute for Regenerative Medicine (CIRM)

Robert Klein, Founder, Chairman, Americans for Cures

Title: “Funding the Future of Medical Research and clinical Trials”

Session 3

1:20-1:45

Steven A. Feldman, PhD, Director of Manufacturing and Process Development, Stanford Center for Cancer Cell Therapy, Stanford University

Title: “Manufacturing and Characterization of Bispecific CD19/22 CAR T Cells for the Treatment of B Cell Malignancies”

1:45-2:10

Zhaohui Ye, PhD, Office of Tissues and Advanced Therapies, Division of Cellular and Gene Therapies, Gene Transfer and Immunogenicity Branch, Food and Drug Administration

Title: “Challenges in Stem Cell-Based Gene Therapy Product Characterization”

Closing Keynote:

2:10-2:55

Introduction of Keynote: Fraser Wright, PhD, Director of Technology Innovation, CDCM, Stanford University

Keynote: Beverly L. Davidson, PhD, Director of the Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia

Title: “Advancing Gene-Based Medicines for the Brain”

2:55-3:00

Closing RemarksMatthew Porteus, MD, PhD, Co-Director, CDCM, Stanford University 

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