Publications

Publication Title Publication Access
Enasidenib drives human erythroid differentiation independently of isocitrate dehydrogenase 2 Link
Gene correction for SCID-X1 in long-term hematopoietic stem cells Link
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells Link
CD34 expression does not correlate with immunophenotypic stem cell or progenitor content in human cord blood products Link
CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells Link
Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting Link
Cas9-AAV6-engineered human mesenchymal stromal cells improved cutaneous wound healing in diabetic mice Link
Differential induction of IFN-α and modulation of CD112 and CD54 expression governs the magnitude of NK cell IFN-γ response to influenza A viruses1 Link
Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6
Identification of preexisting adaptive immunity to Cas9 proteins in humans Link
High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cells Link
The TRACE-Seq method tracks recombination alleles and identifies clonal reconstitution dynamics of gene targeted human hematopoietic stem cells Link
Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function Link
CRISPR/Cas9 Beta-globin Gene Targeting in Human Hematopoietic Stem Cells Link
Engineering monocyte/macrophage−specific glucocerebrosidase expression in human hematopoietic stem cells using genome editing Link
Gene Editing Rescues in vitro T Cell Development of RAG2-Deficient Induced Pluripotent Stem Cells in an Artificial Thymic Organoid System Link