Colin Carpenter, PhD
Project: Tri-modality Molecular Surgical Guidance Integrated into a Laparoscope
In this seed grant, we will build an intra-operative laparoscope that is sensitive to multiple contrast mechanisms that are currently used in the clinic, such as optical and radio-emission probes, as well as a newly developed imaging modality, X-ray luminescence imaging. The end-result of this 1-year project will be:
- the fabrication of a custom laparoscope
- the characterization of this system
- initial proof-of-principle animal studies to demonstrate its potential for surgical guidance.
Mark Cutkosky, PhD
Project: Development and testing of tools with opto-thermal actuation for MRI-guided interventions
Michael Hsieh, MD, PhD
Project: Single Cell Magnetic Resonance Imaging of Infections Using Bacterial Magnetite
The aims of this study are to: optimize the magnetotactic properties of uropathogenic bacteria, analyze the temporal and spatial kinetics of intracellular bacterial community (IBC) formation in the bladder and during ascending infection, and define how biofilm-related genes modulate IBC formation at the single cell level.