Frontiers in Oncology
8th Annual Karl G. Blume, MD, Memorial Lecture
Banks Of 3rd Party Donor-Derived Virus-Specific T-Cells Of Defined Epitope Specificity And HLA Restriction Providing “Off-The-Shelf” Treatment For Drug Refractory EBV+ Lymphomas And CMV Infections In Marrow And Solid Organ Transplant RecipientsErin Kobetz, PhD, MPH
August 17, 2021
Richard J. O’Reilly, MD is the Claire L. Tow Chair in Pediatric Oncology Research and former Chair of the Department of Pediatrics at Memorial Sloan Kettering Cancer Center. As Chief of the Bone Marrow Transplantation Services in both the Departments of Pediatrics and Medicine, Dr. O'Reilly pioneered transplantation approaches for patients who lack HLA matched siblings. He and his colleagues introduced the use of marrow transplants from matched unrelated donors and thereafter T- cell depleted transplants from HLA half matched donors for children with lethal immune deficiencies and both children and adults with leukemia. In 1994, he introduced the use of transplant donor T-cells for the treatment of EBV-induced lymphomas. Currently, he is evaluating adoptive cell therapy employing banked partially HLA-matched and appropriately HLA restricted T-cells from third party healthy donors for viral infections and leukemias, conducting Phase I and II trials testing adoptive transfer of these virus-specific and tumor-specific T-cells following T-cell depleted HCT as a therapeutic approach for EBV lymphoproliferative disease, drug resistant CMV infections and leukemic relapse in the post-transplant period.
Frontiers in Oncology
Frontiers in Oncology, a recurring seminar series organized by the Stanford Cancer Institute, is designed to highlight innovations in cancer research across the spectrum of basic, translational, clinical and population science. The dynamic speakers represent a broad range of disciplines and expertise from both Stanford faculty and national thought leaders. The audience for this seminar series includes Stanford faculty, trainees and staff as well as anyone in the broader community with an interest in cancer research. Each recorded seminar is approximately 1 hour in length.
Join us on Zoom: http://bit.ly/FIO-Live
Zoom Meeting ID: 918 9681 9052
8:00 am – 9:00 am
- Multi-level Studies to Address Cancer Health Disparities: From Omics to Structural and Social Determinants of Health , Scarlett Lin Gomez, MPH, PhD ; Helen Diller Family Comprehensive Cancer Center - November 2, 2021
- Stephen Chanock, MD; National Institute of Health - November 16, 2021
- Kornelia Polyak, MD, PhD; Dana-Farber Cancer Institute - December 7, 2021
You may also be interested in the Frontiers in Cancer Clinical Translation Seminar Series sponsored by the Division of Oncology.