How to Participate
Research Participants Invited
The Human Motor Control and Neuromodulation Lab is always looking for motivated individuals to participate in our research studies. Research participants are invited to the Human Motor Control and Neuromodulation Lab at the Stanford Movement Disorders Center located at the Stanford Neuroscience Health Center.
SPRING study
Trial number: NCT04043403
Description: The SPRING study aims to investigate the safety and feasibility of adaptive deep brain stimulation (aDBS) for impaired gait and freezing of gait in Parkinson’s disease with the Medtronic Percept PC and RC system. Research testing occurs over multiple half-days or full days and includes behavioral kinematic tests such as: repetitive alternating finger-tapping task, stepping in place task, and turning-and-barrier course task.
Contact
(650) 497-9572
NBM study
Trial number: NCT05968703
Description: The NBM study is a pilot clinical trial investigating the safety, tolerability, and effect of a novel deep brain stimulation approach for cognitive and cognitive-motor symptoms in people with Parkinson’s disease. The study involves a modification of the traditional DBS surgery. In addition to the standard 2 leads placed within the Subthalamic Nucleus (STN) to treat motor symptoms, 2 additional leads will be placed in the Nucleus Basalis of Meynert (NBM) to treat cognitive and cognitive-motor symptoms within the same surgical procedure. The leads in the NBM will also use novel stimulation patterns using an investigational software: Boston Scientific Chronos. DBS in the STN will be active throughout the day and night (i.e., 24/7) using typical stimulation settings, as is the standard clinical care, whereas the novel NBM DBS will only be active for 1 hour per day (~10-11 am). Participants will be in the study for approximately 2.5 years.
Contact
(650) 498-0567
Quantitative Digitography study (QDG) study
Description: The QDG or Quantitative Digitography study aims to upgrade and validate a portable computerized keyboard for quantifying movement in people who have difficulty with movement and/or symptoms of neurological disease using a finger-tapping task. Research testing occurs over hour long visits at which both healthy controls and participants with PD perform a series of finger-tapping tasks and answer questionnaires.
Contact
(650) 723-6709
C-MIND study
Description: The C-MIND study aims to investigate the patterns of degeneration of brain structures that may underlie cognitive and cognitive-motor symptoms in people with Alzheimer’s disease, Parkinson’s disease, and dementia with Lewy bodies. Participation would require four research visits, which include completing cognitive, neuropsychological, and mobility assessments, and an MRI scan.
Contact
(650) 736-2004