Group Leader
Bio
Curriculum Vitae
Dr. Bogyo received a B.Sc. degree in Chemistry from Bates College in 1993 and a Ph.D. in Biochemistry from the Massachusetts Institute of Technology in 1997. After completion of his degree he was appointed as a Faculty Fellow in the Department of Biochemistry and Biophysics at the University of California, San Francisco. Dr. Bogyo served as the Head of Chemical Proteomics at Celera Genomics from 2001 to 2003 while maintaining an Adjunct Faculty appointment at UCSF. In the Summer of 2003 Dr. Bogyo joined the Department of Pathology at Stanford Medical School and was appointed as a faculty member in the Department of Microbiology and Immunology in 2004. His interests are focused on the use of chemistry to study the role of proteases in human disease. In particular his laboratory is currently working on understanding the role of cysteine proteases in tumorgenesis and also in the life cycle of human parasites and bacterial pathogens. Dr. Bogyo currently serves on the Editorial Board of Biochemical Journal, Cell Chemical Biology, Molecular and Cellular Proteomics and is an Academic Editor at PLoS One. Dr. Bogyo is a consultant for several biotechnology and pharmaceutical companies in the Bay Area and is a founder and board member of Akrotome Imaging and Facile Therapeutics.
Postdoctoral Fellows
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Philipp completed his B.Sc. in Chemistry at the University of Vienna, Austria, in 2015, under the mentorship of Prof. Nuno Maulide. After an exchange semester at Lund University, Sweden, he earned his M.Sc. from the University of Vienna in 2018, focusing on biological chemistry, and working on glycopeptides and antiviral proteins under the guidance of Prof. Christian F. W. Becker. He pursued his Ph.D. in the group of Prof. Jeffrey W. Bode at ETH Zurich, working on new strategies for chemical protein synthesis, chemoselective reactions, chemical libraries, and bioconjugation techniques. His doctoral research focused on using organoboron chemistry to access and modify bioactive proteins and on developing linker strategies to produce glycoconjugate vaccine candidates against bacterial infections. After completing his Ph.D. in 2025, he joined the Bogyo lab in August 2025 to leverage chemical libraries and phage-display approaches for developing highly selective probes and inhibitors against various targets.
Bio
Ife earned his B.Sc. in microbiology from the University of Nigeria in 2016. He performed undergraduate research in enzyme biochemistry in the laboratory of Prof. Tochukwu Nwagu where he studied the production of raw starch-degrading amylase from a microbial isolate. Following his first degree, he did post-baccalaureate research in the laboratory of Prof. Anthony Attama at the same institution. His work was focused on the characterization of probiotic yeast isolates. Ife went on to earn his Ph.D. in microbiology and molecular genetics at Michigan State University in 2024 under the mentorship of Prof. Robert Abramovitch. His graduate work was focused on the use of chemical genetic approaches to decipher the mechanisms-of-action of novel nitro-containing compounds that inhibit the growth of Mycobacterium tuberculosis and M. abscessus. In August 2024, Ife joined the Bogyo lab, and his work has revolved around the development of covalent antibiotics, photodynamic therapy for otitis media, and covalent phage display against various targets.
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Kristyna completed her B.Sc. in Molecular Biology at Charles University in 2012, followed by an M.Sc. in Virology in 2014, where she conducted research on the use of chemically-modified virus-like particles as targeting agents. After completing her M.Sc., she joined the group of Dr. Petr Bartunek at the Institute of Molecular Genetics to study steroid hormone nuclear receptors in cancer using high-throughput phenotypic screening. Kristyna then pursued her Ph.D. in the Konvalinka lab at the Institute of Organic Chemistry and Biochemistry under the mentorship of Prof. Jan Konvalinka. She focused on ligand discovery using various selection methods and the use of polymer chemistry to target immune receptors in autoimmune diseases and cancer immunotherapy. After completing her Ph.D. in 2022, she joined the Bogyo lab to investigate microbial proteases involved in inflammatory bowel disease.
Bio
Lynna completed her B.Ch.E. in Chemical Engineering from the University of Minnesota – Twin Cities (2014 – 2018). There, she worked in the laboratory of Prof. Ben Hackel to engineer improvements in antimicrobial protein variants against vancomycin-resistant Enterococcus. After briefly working in the aerospace industry, she joined the Bioengineering Ph.D. program at Rice University where she conducted multidisciplinary research at the intersection of drug delivery, chemical biology, and microbiology under the mentorship of Profs. Kevin McHugh and Laura Segatori (2020 – 2025). Her thesis work focused on rationally designing small molecule drugs capable of targeting bacteria in situ for a variety of applications, including achieving immunosuppression in the colon in proximity to resident gut commensals and immune potentiation at sites of infection. She joined the Bogyo lab in September of 2025 and is working on developing protease-activated probes for cancer imaging applications, including endoscopic detection of (pre)malignant colorectal lesions.
Bio
Emily completed her Ph.D. (2017) and M.D. (2020) through the Emory University Medical Scientist Training Program. She did her Ph.D. work in the lab of Dr. Shonna McBride. Her thesis work primarily focused on genetic mechanisms of the Clostridioides difficile response to host-produced antimicrobials. She subsequently continued her medical training as an Internal Medicine resident at Stanford University (2020-2023). Emily joined the Bogyo lab in July 2023 and is interested in developing in vivo imaging techniques for bacterial infections.
Bio
Jeyun received his Pharm.D. from Pusan National University in 2016 and completed his Ph.D. research in the laboratory of Prof. Hwayoung Yun at the same university in 2021. His thesis studies focused on the first total synthesis of anmindenol A and optimization of 2-anilinopyrimidine-based selective inhibitors against TNBC cells. After working as a senior research scientist at Chong Kun Dang for a year, Jeyun joined the Bogyo lab as a postdoctoral fellow in May of 2022. He is currently working on the development of highly selective inhibitors and probes targeting specific serine hydrolases in pathogenic bacteria and parasites.
Bio
Tulsi received her B.Sc. degree in Biotechnology (2009) from Mohanlal Sukhadiya University Udaipur and her M.Sc.degree in Biotechnology (2011) from H. N. B. Garhwal University Srinagar, India. She then joined the Department of Mathematics, Maulana Azad National Institute of Technology Bhopal, India to pursue M. Tech in Bioinformatics (2014). She worked under the guidance of Prof. K.R. Paradasni and Prof. Neeru Adlakha to identify riboswitches in Clostridium difficile and their small-molecule binders using an in silico approach. In January 2015, she started her Ph. D. work in the laboratory of Dr. Ishu Saraogi at the Indian Institute of Science Education and Research, Bhopal. Her thesis focused on studying essential structural features that regulate protein-protein interaction in the bacterial Hsp70 system and the identification of small molecule inhibitors of DnaK. Tulsi joined the Bogyo lab in March 2022. Her current interest is in characterizing the function of serine hydrolases in pathogenic bacteria and developing selective inhibitors using diverse chemical libraries and phage-display approaches.
PhD Students
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Hai earned his B.A. in Chemistry from Johns Hopkins University in 2023. From February 2021 to May 2024, he worked in the lab of Prof. Kenneth Karlin, focusing on spectroscopic, reactivity, and mechanistic studies of synthetic copper dioxygen and heme/copper-dioxygen complexes. His research aimed to elucidate the process of oxygen activation by copper-containing metalloenzymes, in particular tyrosinase and cytochrome c oxidase. In the Fall of 2024, Hai joined the Ph.D. program in Chemistry at Stanford and became a member of the Bogyo Lab in the Spring of 2025. He is currently working on the development of protease-activated probes and covalent cyclic peptides for use as imaging agents and therapeutics.
Bio
Laney earned her B.Sc. in Chemistry and Biology from the Massachusetts Institute of Technology in 2022. Post-graduation, she worked as a research assistant at a biotech startup in Cambridge called Cerberus Therapeutics, where she helped to engineer nanobody-drug conjugates that could antigen-specifically immunomodulate T cells in autoimmune and infectious diseases. Laney started her PhD in Chemical and Systems Biology at Stanford in Fall 2024 and joined the Bogyo Lab soon after, where she is now interested in studying microbial proteases from the gut microbiome that regulate receptors associated with inflammatory bowel disease.
Bio
Alyssa graduated with distinction from Duke University in 2020 with a B.A. in Chemistry. While at Duke, she conducted research in the lab of Dr. Emily Derbyshire characterizing the role of host proteins in Toxoplasma gondii infection. Post-graduation, Alyssa worked as a research technician in the lab of Dr. Rustem Ismagilov at the California Institute of Technology where she supported graduate research focused on the development of molecular biology-based diagnostics for the sensitive detection of viral and bacterial pathogens in a range of sample types. In the Fall of 2023, Alyssa began her Ph.D. program in the Department of Microbiology and Immunology at Stanford. She joined the Bogyo lab in Spring of 2024 and is interested in using covalent inhibitors to target fatty acid biosynthesis in Clostridioides difficile growth and sporulation.
Undergraduates
Bio
Anna is a summer undergraduate research student in the Bogyo Lab. She completed high school at Los Altos High School in 2023. She is currerntly a Junior at Wellesley College majoring in Chemistry and Sociology. She worked in the Bogyo Lab in the Summer of 2024 and plans to return for the Summer of 2025.
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Max is summer undergraduate student in the Bogyo Lab. He completed high school at Larchmont Charter High Scool in 2023 and is currently a Junior at Claremont McKenna College in Claremont, CA, majoring in Biochemistry. He will return to the Bogyo Lab in the Summer of 2025.