Stanford BMT-CT ASH Abstracts 2024

68 Interim Results from a Phase 2 Pivotal Study (DALY II USA) of Tandem CD20-CD19-Directed Non-Cryopreserved CAR-T Cells - Zamtocabtagene Autoleucel (Zamto-Cel) in Patients with Relapsed/Refractory Diffuse Large B Cell Lymphoma

Nirav N. Shah, MD, Richard T. Maziarz, MD, Caron A. Jacobson, MD, MMSc, Patrick B. Johnston, MD, PhD, Sunil Abhyankar, MD, Iris Isufi, MD, Miguel Angel Perales, MD, Monalisa Ghosh, MD, Matthew Ulrickson, MD, Allison C. Rosenthal, DO, Javier L. Munoz, MD, MS, MBA, Nancy M. Hardy, MD, Aaron P. Rapoport, MD, Reem Karmali, MD, Farrukh T. Awan, MD, Matthew Stuart McKinney, MD, Mitchell Horwitz, MD, Matthew Lunning, DO, Nathan Denlinger, DO, MS, Marek Ancukiewicz, PhD, Madhavi Nallewar, MD, Kimberly C Coleman, RN, Esther Eromosele, MD, Remigiusz Kaleta, MD, Johanna Theruvath, MD, Anna Wijatyk, MD and David B. Miklos, MD, PhD

Saturday, December 7, 2024: 9:45 AM

https://ash.confex.com/ash/2024/webprogram/Paper208539.html

 

69 CD22-Directed CAR T-Cell Therapy for Large B-Cell Lymphomas Progressing after CD19-Directed CAR T-Cell Therapy: Continued Durable Remissions at 3-Year Follow-up

Anne Marijn Kramer, MD, PhD, John H. Baird, MD, Hrishikesh Srinagesh, MD, MSCR, Emily Egeler, Kendall Levine, Annie K. Brown, MS, Sharon Mavroukakis, MS, Kristen Cunanan, PhD, Yi-Jiun Su, MD, Neha Agarwal, MS, Mark P. Hamilton, MD, PhD, Sushma Bharadwaj, MD, Sally Arai, MD, Laura Johnston, MD, Robert Lowsky, MD, Everett H. Meyer, MD, PhD, Robert S. Negrin, MD, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, MD, MA, Hitomi Hosoya, MD, PhD, Parveen Shiraz, Surbhi Sidana, MD, Wen-Kai Weng, MD, PhD, Vanessa E. Kennedy, MD, Melody Smith, MD, MS, Saurabh Dahiya, MD, Kara L. Davis, DO, Sneha Ramakrishna, MD, Liora Michal Schultz, MD, Ramya Tunuguntla, PhD, Steven A. Feldman, PhD, Lori Muffly, MD, Crystal L. Mackall, MD, David B. Miklos, MD, PhD and Matthew J. Frank

Saturday, December 7, 2024: 10:00 AM at Pacific Ballroom Salons 18-19 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper198544.html

 

96 Single Institution Analysis of Lymphoma Treatment Related Post-CAR Myeloid Neoplasms

Mark Hamilton, MD, Nick Phillips, Dasom Lee, MD, Zachary Ehlinger, MS, Anne Marijn Kramer, MD, PhD, Hrishikesh Srinagesh, Zinaida Good, PhD, Xiaoman Kang, BS, Mari Olsen, BS, Chih Long Liu, PhD, Feng Tian, PhD, Brian J. Sworder, MD, PhD, Hitomi Hosoya, MD, PhD, Joseph G. Schroers-Martin, MD, Sushma Bharadwaj, MD, Sally Arai, MD, Laura Johnston, MD, Robert Lowsky, MD, Everett H. Meyer, MD, PhD, Robert S. Negrin, MD, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, MD, MA, Parveen Shiraz, Surbhi Sidana, MD, Wen-Kai Weng, MD, PhD, Vanessa E. Kennedy, MD, Melody Smith, MD, MS, Lori Muffly, MD, David Kurtz, MD, PhD, Saurabh Dahiya, MD, FACP, Matthew J. Frank, MD, PhD, Crystal L. Mackall, MD, Bita Sahaf, David B. Miklos, MD, PhD and Ash A. Alizadeh, MD, PhD

Saturday, December 7, 2024: 10:45 AM at Marriott Grand Ballroom 11-13 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper205378.html

 

238 Treatment Patterns and Outcomes Following Progression of Disease Post-CAR-T Therapy in Relapsed or Refractory Mantle Cell Lymphoma: A Multicenter Analysis

Zachary D. Epstein-Peterson, MD, Anath C. Lionel, MD PhD, Ashlee Joseph, BS, Esther Drill, DrPH, Suheil Albert Atallah-Yunes, MD, Taylor R. Brooks, MD, Elise A. Chong, MD, Emeline R. Chong, Jamie Dela Cruz, Matthew J. Frank, Andrew Ip, MD, MSc, Madiha Iqbal, MD, Caron A. Jacobson, MD, MMSc, Manali K. Kamdar, MD, Reem Karmali, MD, Kami J. Maddocks, MD, Matthew Matasar, MD, MS, Reid W. Merryman, MD, Javier Munoz, MD, Peter A. Riedell, MD, Christine E. Ryan, MD, Gilles Salles, MD, PhD, Craig S. Sauter, MD, Yazeed Sawalha, MD, Roni Shouval, MD, PhD, Navika Shukla, MD, Alexander V. Stanisic, MD, Dylan Therwhanger, MD, Herman Van Besien, md, Yucai Wang, MD, PhD, Samuel Yamshon, MD, Andrew D. Zelenetz, MD, PhD, Maria Lia Palomba, MD, Preetesh Jain, MD, MBBS, PhD, DM and Anita Kumar, MD

Saturday, December 7, 2024: 2:45 PM at Marriott Grand Ballroom 11-13 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper192995.html

 

368 CCL8/CCL13-Producing Tumor-Associated Macrophages Linked to Poor Outcomes after CAR T Cell Therapy for LBCL

Kelvin C. Mo, BA, Christine Y. Yeh, MS, Mark Hamilton, MD, Jay Y Spiegel, MD, FRCPC, Moksha Desai, MS, Zachary Ehlinger, MS, Warren D. Reynolds, BS, Eric Yang, MD, PhD, Michael G. Ozawa, MD, PhD, Yiyun Chen, PhD, Snehit Prabhu, PhD, Matthew J. Frank, MD, PhD, Lori Muffly, MD, Gursharan K. Claire, MPH, Sushma Bharadwaj, MD, Saurabh Dahiya, MD, FACP, Katherine A. Kong, MS, Elena Sotillo, PhD, Bita Sahaf, Sylvia Plevritis, PhD, David B. Miklos, MD, PhD, Crystal L. Mackall, MD and Zinaida Good, PhD

Saturday, December 7, 2024: 4:15 PM

https://ash.confex.com/ash/2024/webprogram/Paper198942.html

 

382 Preliminary Safety and Efficacy of Myeloablative Orca-Q with No GvHD Prophylaxis for Treatment of Advanced Hematologic Malignancies

Mehrdad Abedi, MD, Samer A. Srour, MD, Amandeep Salhotra, MD, Rasmus T. Hoeg, MD, Edmund K. Waller, MD, PhD, Hannah Choe, MD, Anna Pavlova, MD, PhD, Tamara Zharkevich, MD, PhD, J. Scott McClellan, MD, PhD, Nathaniel B. Fernhoff, PhD, Everett H. Meyer, MD, PhD and Robert Lowsky, MD

Saturday, December 7, 2024: 4:45 PM at Room 6CF (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper204256.html

 

386 Safety and Efficacy of Chimeric Antigen Receptor T-Cell Therapy in Octogenarian Patients (Aged ³ 80) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Dasom Lee, MD, Sushma Bharadwaj, MD, Masooma S Rana, MBBS, Alexandria Jensen, William Wang, Nima Ghalehsari, MD, Bita Sahaf, Jayasindhu Mallampet, Sarah Elkordy, Theresa Latchford, Sally Arai, MD, Laura Johnston, MD, Hitomi Hosoya, MD, PhD, Robert Lowsky, MD, Robert S. Negrin, MD, Andrew R. Rezvani, Judith Shizuru, Everett H. Meyer, MD, PhD, Parveen Shiraz, Lekha Mikkilineni, MD, MA, Wen-Kai Weng, MD, PhD, Lauren S. Maeda, Melody Smith, MD, MS, Surbhi Sidana, MD, Lori Muffly, MD, Matthew J. Frank, David B. Miklos, MD, PhD and Saurabh Dahiya, MD, FACP

Saturday, December 7, 2024: 4:15 PM at Room 6B (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper201822.html

 

470 Real-World (RW) Outcomes of Lisocabtagene Maraleucel (liso-cel) As Second-Line (2L) Therapy in Patients (pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL): First Results from the Center for International Blood and Marrow Transplant Research (CIBMTR) Registry

Maria Silvina Odstrcil Bobillo, MD, Swetha Kambhampati, MD, Dasom Lee, Bradley D. Hunter, MD, MPH, Ogechukwu Egini, MD, MS, Krish Patel, MD, Patrick M. Reagan, MD, David Bernasconi, MSc, Soyoung Kim, PhD, Charimar Santiago Parrilla, MPH, Tracy Krimmel, MSN, DNP, Fei Fei Liu, GDCE, MBA, Debasmita Roy, PhD, Sairah Ahmed, MD, Jennifer L. Crombie, MD, Saurabh Dahiya, MD, FACP, Mehdi Hamadani, MD, Catherine J. Lee, MD, MSc, Marcelo C. Pasquini, MD, MS, Mazyar Shadman, MD, MPH, Alex F. Herrera, MD and Matthew Frigault, MD, MS

Sunday, December 8, 2024: 9:45 AM at Marriott Grand Ballroom 8-9 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper199723.html

 

523 Efficacy and Safety of Brexucabtagene Autoleucel for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in Patients Aged 60 and Above

Ibrahim Muhsen, MD, Anjali S. Advani, MD, Gregory W Roloff, MD, Nikeshan Jeyakumar, MD, Katharine Miller, PhD, MPH, Amy Zhang, PhD, Katherine C. Sutherland, PA-C, Michael R. Grunwald, MD, Vamsi K. Kota, MD, Jacob Boccucci, MD, Matthew Ulrickson, MD, Joshua Sasine, MD, Ibrahim Aldoss, MD, Tamer Othman, MD, Sumithira Vasu, MD, MBBS, Ran Reshef, MD, MSc, Marlise R. Luskin, MD, Evan C. Chen, MD, Chenyu Lin, MD, Amelia Langston, MD, Ryan D. Cassaday, MD, Noam E. Kopmar, MD, Stephanie B. Tsai, Timothy E O'Connor, MD, Talal Hilal, MD, Rawan Faramand, MD, Jae H. Park, MD, Yannis K. Valtis, MD, Melhem M. Solh, MD, Evandro Bezerra, MD, Jessica T. Leonard, MD, Simone E. Dekker, MD, PhD, Navneet Majhail, MD, MS, FASTCT, Minoo Battiwalla, MD, Shahbaz A. Malik, MD, John Mathews, MD, Paul Shaughnessy, MD, Luke Mountjoy, DO, Rasmus T. Hoeg, MD, Caspian H. Oliai, MD, Vishal Gupta, MD, Divya Koura, MD, Kaitlyn C Dykes, MD, BS, Aaron C. Logan, MD, PhD, Muthu V. Kumaran, MD, Wendy Stock, MD, Marc Schwartz, MD, Veronika Bachanova, MD, PhD, Sean Tracy, MD, PhD, Kristen M. O'Dwyer, MD, Jozal Moore, MD, Catherine J. Lee, MD, MSc, Maria Silvina Odstrcil Bobillo, MD, Noelle Frey, MD, MS, Matthew P Connor, MD, Omer Jamy, MD, Michael Daunov, DO, Abdullah Ladha, MD, George Yaghmour, MD, Clayton Jackson, MD, Vivian Irrizary Gatell, MD, Olalekan O. Oluwole, MD, MPH, MBBS, Bhagirathbhai R. Dholaria, MBBS, Vinod Pullarkat, MD, Akil Merchant, MD, Bijal D Shah, MD, Lori Muffly, MD and LaQuisa Hill, MD

Sunday, December 8, 2024: 9:30 AM

https://ash.confex.com/ash/2024/webprogram/Paper210682.html

 

526 Real-World Early Outcomes of Second-Line Axicabtagene Ciloleucel (Axi-Cel) Therapy in Patients (Pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Dasom (Caroline) Lee, MD, Swetha Kambhampati, MD, Maria Silvina Odstrcil Bobillo, MD, Babatunde Adedokun, MD, PhD, Mazyar Shadman, MD, MPH, Amanda L. Olson, MD, Alex F. Herrera, MD, Catherine J. Lee, MD, MSc, Caron A. Jacobson, MD, MMSc, Matthew Bye, MPH, Mehdi Hamadani, MD, Soyoung Kim, PhD, Saurabh Dahiya, MD, FACP, Zhen-Huan Hu, MPH, Kelly Speth, PhD, Christina To, MD, Debbie L. Mirjah, MD, Timothy Best, PhD, Frederick L. Locke, MD, Nausheen Ahmed, MD, Michael T. Tees, MD, MPH, Marcelo C. Pasquini, MD, MS and Sairah Ahmed, MD

Sunday, December 8, 2024: 10:15 AM at Pacific Ballroom Salons 24-26 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper199139.html

 

527 Real-World Trends of Cytokine Release Syndrome and Neurologic Events, and Pattern of Their Management Among Patients Receiving Axicabtagene Ciloleucel for Relapsed or Refractory (r/r) Large B-Cell Lymphoma (LBCL) in the US: A CIBMTR Report

Jiasheng Wang, MD, Shakthi Bhaskar, MD, Babatunde Adedokun, MD, PhD, Olalekan O. Oluwole, MD, MPH, MBBS, Leland Metheny, MD, Amy Moskop, MD, Caron A. Jacobson, MD, MMSc, Geoffrey Shouse, PhD, DO, Sairah Ahmed, MD, Armin Ghobadi, MD, Saurabh Dahiya, MD, Jiali Yan, Zhen-Huan Hu, MPH, Timothy Best, PhD, Jenny J. Kim, MD, MS, Debbie L. Mirjah, MD, Marcelo C. Pasquini, MD, MS and Frederick L. Locke, MD

Sunday, December 8, 2024: 10:30 AM

https://ash.confex.com/ash/2024/webprogram/Paper209093.html

 

570 Outcomes of Autologous Stem Cell Transplant in Older Adults with Relapsed/Refractory Classic Hodgkin Lymphoma

Sanjal H. Desai, MBBS, Michael A Spinner, MD, Alice Sykorova, Veronika Bachanova, MD, PhD, Andrew M Evens, DO MBA MSc, Gaurav Goyal, MD, Brad S. Kahl, MD, Kathleen Dorritie, MD, Jacques Azzi, Vaishalee P Kenkre, MD, Cheryl Chang, BA, Jozef Michalka, MD, Stephen M. Ansell, MD, PhD, Brendon Fusco, MD, Nuttavut Sumransub, MD, Haris Hatic, DO, Raya Saba, MD, MS, Uroosa Ibrahim, MD, Elyse I Harris, MD, Harsh R. Shah, DO, Nina D. Wagner-Johnston, MD, Sally Arai, MD, Grzegorz S. Nowakowski, MD, Heidi Mocikova, MD, Deepa Jagadeesh, MD, Kristie A. Blum, MD, Catherine S. Diefenbach, MD, Siddharth Iyengar, MD, K. C. Rappazzo, MD, Firas Baidoun, MD, Yun Choi, MD, Vit Prochazka, MD, PhD, Ranjana H. Advani, MD and Ivana N. Micallef

Sunday, December 8, 2024: 1:15 PM at Ballroom 20CD (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper199845.html

 

609 Predictors of Early Safety Outcomes with Axicabtagene Ciloleucel (axi-cel) in Patients with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Christopher Strouse, MD, Umar Farooq, MD, Roni Shouval, MD, PhD, Anusha Vallurupalli, MD, Amy Moskop, MD, Caron A. Jacobson, MD, MMSc, Frederick Locke, MD, John H. Baird, MD, Paolo Strati, MD, Dilan A. Patel, MD, Saurabh Dahiya, MD, Michael T. Hemmer, MS, Brad Du, MPH, Clare Spooner, MBBS, BSc, Jenny J. Kim, MD, MS, Debbie L. Mirjah, MD, Zhen-Huan Hu, MPH, Marcelo C. Pasquini, MD, MS and Yi Lin, MD, PhD

Sunday, December 8, 2024: 12:30 PM

https://ash.confex.com/ash/2024/webprogram/Paper207976.html

 

618 Acute Myeloid Leukemias: Biomarkers and Molecular Marker in Diagnosis and Prognosis: Deciphering the Mechanisms Underlying Prognosis

Moderators: Vanessa E. Kennedy, MD, University of California- San Francisco and Sarah Skuli, MD, PhD

Sunday, December 8, 2024: 4:30 PM-6:00 PM at Seaport Ballroom EFGH (Manchester Grand Hyatt San Diego)

https://ash.confex.com/ash/2024/webprogram/Session27213.html

 

655 Multiple Myeloma: Cellular Therapies: Unleashing Cell Therapies Against Myeloma

Moderators: Surbhi Sidana, MD, Stanford University and Myo Htut, MD,

Monday, December 9, 2024: 4:30 PM-6:00 PM at Pacific Ballroom Salons 24-26 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Session27278.html

 

679 Safe and Effective Combination of Donor-Derived, Allogeneic CD19/CD22-CAR T Cells with Myeloablative Graft-Engineered Allo-HCT for High-Risk B-ALL

Lori Muffly, MD, Snegha Ananth, MBBS, Lindsay Danley, Caroline Wagner, Diana Kordek, Kimi DeNoble, Ayesha Fraser, Emily Egeler, Alfonso Molina, MD, MPH, Zachary Ehlinger, MS, Moksha Desai, MS, Hossein Daghagh, Ramya Tunuguntla, PhD, Annie K. Brown, MS, Raquel Ibañez, Anne Marijn Kramer, MD, PhD, Zinaida Good, PhD, Sally Arai, MD, Laura Johnston, MD, Robert Lowsky, MD, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, MD, MA, Parveen Shiraz, Surbhi Sidana, MD, Wen-Kai Weng, MD, PhD, Vanessa E. Kennedy, MD, Sushma Bharadwaj, MD, Saurabh Dahiya, MD, Matthew J. Frank, MD, PhD, Everett H. Meyer, MD, PhD, Robert S. Negrin, MD, Steven A. Feldman, PhD, Crystal L. Mackall, MD, Bita Sahaf, David B. Miklos, MD, PhD and Melody Smith, MD, MS

Sunday, December 8, 2024: 4:30 PM-6:00 PM at Marriott Grand Ballroom 2-4 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper211959.html

 

685 The Composite Health Risk Assessment Model (CHARM) Predicts Risks of Toxicities, Functional and Cognitive Decline Among Survivors of Allogeneic Hematopoietic Cell Transplantation (allo-HCT): A Prospective BMT-CTN Study 1704

Mohamed Sorror, MD, MSc, Wael Saber, MD, MS, Brent R. Logan, PhD, Nancy Geller, PhD, Anna Bellach, Ph.D., Jianqun Kou, MS, William A. Wood, MD, MPH, John M. McCarty, MD, Thomas G. Knight, MD, Lyndsey Runaas, MD, Laura Johnston, MD, Jeremy Walston, Ryotaro Nakamura, MD, Asmita Mishra, MD, MBA, Joseph Uberti, MD, PhD, Parastoo B Dahi, MD, Jennifer N. Saultz, DO, Shannon R McCurdy, MD, Lawrence E Morris, MD, Philip Imus, MD, William J. Hogan, MD, Kalyan Nadiminti, MBBS, Vijaya Raj Bhatt, MD, Rebecca Olin, MD, Joseph E. Maakaron, MD, Ronald Sobecks, MD, Sarah A. Wall, MD, MPH, Deborah Mattila, BA, Bailey Protz, Steven Michael Devine, MD, Mary M. Horowitz, MD and Andrew Artz, MD, MS

Sunday, December 8, 2024: 4:30 PM at Room 6B (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper194414.html

 

694 Observational Comparison of Overall Survival between Phase 1b Orca-T and Registry-Based Post-Transplant Cyclophosphamide Patients

Caspian H. Oliai, MD, Rasmus T. Hoeg, MD, Arpita Gandhi, MD, Lori Muffly, MD, Samer A. Srour, MD, Rohtesh S. Mehta, MD, MPH, Edmund K. Waller, MD, PhD, Robert Lowsky, MD, Sagar S. Patel, MD, Bhagirathbhai R. Dholaria, MBBS, Jeremy Pantin, MD, Amandeep Salhotra, MD, Joseph P. McGuirk, DO, Steven Michael Devine, MD, Alexandra Gomez-Arteaga, MD, Rawan Faramand, MD, Roni Tamari, MD, Jennifer L Holter-Chakrabarty, MD, Betty K. Hamilton, MD, Antonio M. Jimenez Jimenez, MD, MSc, Anna Pavlova, MD, PhD, Nathaniel B. Fernhoff, PhD, J. Scott McClellan, MD, PhD, Mehrdad Abedi, MD, Robert S. Negrin, MD and Everett H. Meyer, MD, PhD

Sunday, December 8, 2024: 5:15 PM at Room 6A (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper205917.html

 

704 Cellular Immunotherapies: Early Phase Clinical Trials and Toxicities: Emerging Targeting Approaches of Cell Therapies for Hematologic Malignancies

Moderators: Lekha Mikkilineni, MD, MA, and Natalie Grover, MD, NULL

Monday, December 9, 2024: 2:45 PM-4:15 PM at Hall B (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Session27288.html

 

723 CDK8 Inhibition Represses Monocyte-like Gene Expression in Acute Myeloid Leukemia Cells and Antagonizes In Vivo Resistance to FLT3 Inhibition

Timothy T. Ferng, MD, Samantha M. Pintar, BA, Vanessa E. Kennedy, MD, Shaheen Kabir, PhD, Theodore C. Tarver III, BS, Veronica Steri, PhD, Paul Phojanakong, BA, Juwita Hübner, MD, Carolina E. Morales, BS, Jose M. Rivera, Aaron C. Logan, MD, PhD, Benjamin Braun, MD, PhD, Elliot Stieglitz, MD, PhD, Luke A. Gilbert, PhD and Catherine C. Smith, MD

Monday, December 9, 2024: 11:00 AM

https://ash.confex.com/ash/2024/webprogram/Paper204168.html

 

748 Primary Analysis of ZUMA-2 Cohort 3: Brexucabtagene Autoleucel (Brexu-Cel) in Patients (Pts) with Relapsed/Refractory Mantle Cell Lymphoma (R/R MCL) Who Were Naive to Bruton Tyrosine Kinase Inhibitors (BTKi)

Tom van Meerten, M.J. Kersten, MD, PhD, Gloria Iacoboni, MD, Georg Hess, MD, Pim Mutsaers, MD, Alejandro Martín García-Sancho, Andre Goy, MD, MS, Eva Gine, MD, Brian T. Hill, MD, PhD, Wen-Kai Weng, MD, PhD, Martin Dreyling, MD, Patrick M. Reagan, MD, Krish Patel, MD, Ahmed Galal, MD, MSc, FRCPC, Charles Herbaux, MD, PhD, Robin Sanderson, FRCPath, PhD, Dan Zheng, PhD, Justyna Kanska, PhD, Wangshu Zhang, PhD, Rita Damico Khalid, DO, Ioana Kloos, MD, FRCPC and Michael Wang, MD

Monday, December 9, 2024: 11:15 AM at Marriott Grand Ballroom 8-9 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper198021.html

 

897 Outcomes of Teclistamab (Tec) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) with Prior Exposure to BCMA-Directed Therapy (BCMA-DT): A Multicenter Study from the U.S. Multiple Myeloma Immunotherapy Consortium

Danai Dima, MD, Mariola A Vazquez-Martinez, MD, James A Davis, PharmD, Utkarsh Goel, MBBS, Aimaz Afrough, Aishwarya Sannareddy, MBBS, Oren Pasvolsky, MD, Beatrice Razzo, MD, Rahul Banerjee, MD, FACP, Jack Khouri, MD, Ariel Grajales-Cruz, Alex Lieberman-Cribbin, Masooma Shifa Rana, Kelley Julian, PharmD, Shaun DeJarnette, Andrew J Portuguese, MD, Mahmoud R. Gaballa, MD, Gabriel De Avila, Sandra Susanibar-Adaniya, MD, Shahzad Raza, MD, Megan M Herr, PhD, Evguenia Ouchveridze, MD, Tiffany Richards, PhD, NP, Hitomi Hosoya, MD, PhD, Lekha Mikkilineni, MD, MA, Gurbakhash Kaur, MD, MA, Daniel Schrum, PharmD, Omar Castaneda, MD, Adriana Rossi, MD, MSc, Chenyu Lin, MD, Peter A. Forsberg, MD, Yi Lin, MD, PhD, Shebli Atrash, MD, Douglas W Sborov, MD, Kenneth H. Shain, MD, PhD, Peter M. Voorhees, MD, Shambavi Richard, MD, Alfred L. Garfall, MD, Doris K. Hansen, MD, Surbhi Sidana, MD, Krina K. Patel, MD, MSc, Andrew J. Cowan, MD, Larry D Anderson Jr., MD, PhD, Hans C. Lee, MD, Faiz Anwer, MD, Christopher Ferreri, MD and Leyla O. Shune, MD

Monday, December 9, 2024: 3:15 PM at Pacific Ballroom Salons 24-26 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper203409.html

 

911 CD22-Directed CAR T Cell Single Cell Multiomic Features Associated with Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (IEC-HS)

Anne Marijn Kramer, MD, PhD, Tara Murty, PhD, Yiyun Chen, PhD, Hrishikesh Srinagesh, MD, MSCR, Mark P. Hamilton, MD, PhD, Kelvin C. Mo, BA, Snehit Prabhu, PhD, Moksha Desai, MS, Adam Kuo, MS, Zachary Ehlinger, MS, Warren D. Reynolds, BS, John H. Baird, MD, Yi-Jiun Su, MD, Neha Agarwal, MS, Bita Sahaf, Lori Muffly, MD, Crystal L. Mackall, MD, David B. Miklos, MD, PhD, Matthew J. Frank and Zinaida Good, PhD

Monday, December 9, 2024: 3:45 PM at Room 6CF (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper198688.html

 

931 Talquetamab Bridging: Paving the Way to B-Cell Maturation Antigen (BCMA) CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma (RRMM)

Binod Dhakal, MBBS, Othman S. Akhtar, MD, Andrew J. Cowan, MD, Shambavi Richard, MD, Reed Friend, Matthew J Rees, MD, Patrick Costello, MS, Mariola Vazquez Martinez, Oren Pasvolsky, MD, Charlotte B Wagner, PharmD, Alexandria Jensen, James A Davis, PharmD, Ran Reshef, MD, MSc, Danai Dima, Rahul Banerjee, MD, FACP, Manisha Bhutani, MD, Omar Nadeem, MD, Ricardo D. Parrondo, MD, Lekha Mikkilineni, MD, MA, Shahzad Raza, MD, Prashant Kapoor, MD, Hitomi Hosoya, MD, PhD, Saurabh Chhabra, MD, Ariel Grajales-Cruz, Mahmoud R. Gaballa, MD, Shonali Midha, MD, Melissa Alsina, MD, Douglas W. Sborov, MD, MS, Krina K. Patel, MD, MSc, Yi Lin, MD, PhD, Christopher J Ferreri, MD, Doris K. Hansen, MD, Luciano J. Costa, MD, PhD and Surbhi Sidana, MD

Monday, December 9, 2024: 2:45 PM at San Diego Ballroom AB (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper202017.html

 

934 Outcomes of Elderly Patients with Relapsed Refractory Multiple Myeloma (RRMM) Treated with Teclistamab: A Multicenter Study from the U.S. Multiple Myeloma Immunotherapy Consortium

Oren Pasvolsky, MD, Danai Dima, MD, Lei Feng, MS, Wenli Dong, Tiffany Richards, PhD, NP, James A Davis, PharmD, Aimaz Afrough, Mariola A Vazquez-Martinez, MD, Aishwarya Sannareddy, MBBS, Utkarsh Goel, MBBS, Rahul Banerjee, MD, FACP, Jack Khouri, MD, Frances N. Cervoni Curet, MD, Mahmoud R. Gaballa, MD, Alex Lieberman-Cribbin, Masooma S Rana, MBBS, Kelley Julian, PharmD, Christopher J Ferreri, MD, Leyla O. Shune, MD, Shaun DeJarnette, Evguenia Ouchveridze, MD, Sandra Susanibar-Adaniya, MD, Andrew J. Portuguese, Hitomi Hosoya, MD, PhD, Lekha Mikkilineni, MD, MA, Gurbakhash Kaur, MD, MA, Adriana Rossi, MD, MSc, Megan M Herr, PhD, Daniel Schrum, PharmD, Chenyu Lin, MD, Shahzad Raza, MD, Yi Lin, MD, PhD, Shebli Atrash, MD, Joseph P. McGuirk, DO, Douglas W Sborov, MD, Peter M. Voorhees, MD, Faiz Anwer, MD, Melissa Alsina, MD, Ciara Louise Freeman, PhD, MSc, FRCPC, MRCP, Alfred L. Garfall, MD, Surbhi Sidana, MD, Andrew J. Cowan, MD, Larry D Anderson Jr., MD, PhD, Doris K. Hansen, MD, Shambavi Richard, MD, Krina K. Patel, MD, MSc, Hans C. Lee, MD and Ariel Grajales-Cruz

Monday, December 9, 2024: 3:30 PM at San Diego Ballroom AB (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper205989.html

 

936 Comparative Safety and Efficacy of Ciltacabtagene Autoleucel and Idecabtagene Vicleucel CAR T-Cell Therapies in Relapsed or Refractory Multiple Myeloma

Doris K. Hansen, MD, Lauren C. Peres, PhD, MPH, Danai Dima, MD, Alicia Richards, PhD, Leyla O. Shune, MD, Aimaz Afrough, MD, Shonali Midha, MD, Binod Dhakal, MBBS, Mehmet H. Kocoglu, MD, Shebli Atrash, MD, Chris Ferreri, MD, Omar Castaneda, MD, James A Davis, PharmD, Evguenia Ouchveridze, MD, Joseph P. McGuirk, DO, Charlotte B Wagner, PharmD, Radhika Bansal, MBBS, Patrick Costello, MS, Kinaya Smith, MD, Alex Lieberman-Cribbin, Gabriel De Avila, Sneha Purvey, MD, Hitomi Hosoya, MD, PhD, Lekha Mikkilineni, MD, MA, Laura B. Oswald, PhD, Gurbakhash Kaur, MD, MA, Oren Pasvolsky, MD, Mahmoud R. Gaballa, MD, Megan M Herr, PhD, Peter A. Forsberg, MD, Murali Janakiram, MBBS, Myo Htut, MD, Sireesha Asoori, MBBS, MPH, Nilesh Kalariya, PhD, RN, Hamza Sloan Hashmi, MD, Ran Reshef, MD, MSc, Douglas W Sborov, MD, Omar Nadeem, MD, Faiz Anwer, MD, Jack Khouri, MD, Shahzad Raza, MD, Djordje Atanackovic, MD, Melissa Alsina, MD, Ciara Louise Freeman, PhD, MSc, FRCPC, MRCP, Frederick L. Locke, MD, Peter M. Voorhees, MD, Larry D Anderson Jr., MD, PhD, Shambavi Richard, MD, Thomas Martin, MD, Yi Lin, MD, PhD, Krina K. Patel, MD, MSc and Surbhi Sidana, MD

Monday, December 9, 2024: 4:00 PM at San Diego Ballroom AB (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper194390.html

 

1042 Superiority of Post-Transplant Cyclophosphamide-Based Graft Versus Host Disease (GvHD) Prophylaxis in Patients 70 Years and Older: A BMT CTN 1703 Post-Hoc Analysis

Sameem Abedin, MD, Qinghua Lian, Michael J Martens, PhD, MHD Monzr M. Al Malki, MD, Hany Elmariah, MD, MS, Mahasweta Gooptu, MD, Karilyn T. Larkin, MD, Brian C. Shaffer, MD, MS, Alison W Loren, MD, Melhem M. Solh, MD, Amin M. Alousi, MD, Omer Jamy, MD, Janny M. Yao, PharmD, Kristy Applegate, Miguel Angel Perales, MD, Leslie Kean, MD, Yvonne A. Efebera, MD, Ran Reshef, MD, MSc, William Clark, MD, MS, Eric Leifer, PhD, Mary M. Horowitz, MD, Richard J. Jones, MD, Javier Bolanos-Meade, MD, Shernan G. Holtan, MD and Mehdi Hamadani, MD

Monday, December 9, 2024: 5:15 PM at Room 6B (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper193827.html

 

1046 Measurable Residual Disease Monitoring By Duplex Sequencing for TP53 in the Post Allogeneic Stem Cell Transplantation Study with Eprenetapopt (APR-246) + Azacitidine Strongly Predicts Outcomes

David Sallman, MD, Amy F McLemore, MS, Rami S. Komrokji, MD, Hany Elmariah, MD, MS, Andrew T. Kuykendall, MD, Nelli Bejanyan, MD, Onyee Chan, MD, Rawan Faramand, MD, Joseph A. Pidala, MD, PhD, Sean J. Yoder, MS, Lia Perez, MD, Taiga Nishihori, MD, Eric Padron, MD, Hugo Francisco Fernandez, MD, Jeffrey E Lancet, MD and Asmita Mishra, MD, MBA

Monday, December 9, 2024: 4:45 PM at Room 6A (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper203903.html

 

1048 Safety of Fedratinib As a Maintenance Strategy after Allogeneic Hematopoietic Cell Transplant for Myeloproliferative Neoplasms

Hany Elmariah, MD, MS, Jongphil Kim, PhD, Eric Hornfeck, Maria Urdiales Kouba, Farhad Khimani, MD, Rawan Faramand, MD, Sayeef Mirza, MD, MPH, Joseph A. Pidala, MD, PhD, Andrew T. Kuykendall, MD, Rami S. Komrokji, MD, Eric Padron, MD, David Sallman, MD, Alison R. Walker, MD, MBA, MPH, Jeffrey E Lancet, MD, Asmita Mishra, MD, MBA, Jose L. Ochoa-Bayona, MD, Lia Perez, MD, Michael Nieder, MD, Claudio Anasetti, MD, Nelli Bejanyan, MD and Taiga Nishihori, MD

Monday, December 9, 2024: 5:15 PM at Room 6A (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper210830.html

 

Blood Buddies: BMT Pediatric and Adult

Panelists: Taxiarchis Kourelis, MD, Mayo Clinic , Miguel Angel Perales, MD, Memorial Sloan Kettering Cancer Center , Carlo Dufour, MD, Hematology Unit, IRCCS G. Gaslini Children's Hospital , Allen R. Chen, MD, Johns Hopkins Kimmel Cancer Center , Sarah M. Larson, MD, UCLA Health , Lori Muffly, MD, Stanford University School of Medicine , Gunjan L. Shah, MD, Memorial Sloan Kettering Cancer Center , Ramzi Abboud, Washington University School of Medicine and Zachary D. Crees, MD, Washington University School of Medicine

Friday, December 6, 2024: 1:30 PM-3:50 PM at Café Sevilla Restaurant (Gaslamp Quarter)

https://ash.confex.com/ash/2024/webprogram/Session26861.html

 

Setting up a Health Services and Outcomes Research Program

Lori Muffly, MD

Monday, December 9, 2024, 12:15 PM-1:15 PM at Room 31 (San Diego Convention Center)

https://ash.confex.com/ash/2024/webprogram/Paper192682.html

 

Interrogating the Impact of the Intestinal Microbiome on Transplant and Cellular Therapies

Chair: Melody Smith, MD, MS, Stanford University School of Medicine

Sunday, December 8, 2024: 9:30 AM-10:45 AM at Marriott Grand Ballroom 11-13 (Marriott Marquis San Diego Marina)

https://ash.confex.com/ash/2024/webprogram/Paper202017.html

 

Plenary Introducer

Melody Smith, MD, MS

Sunday, December 8, 2024, 2:00 PM-4:00 PM

Program: Marquee Sessions

https://ash.confex.com/ash/2024/webprogram/Paper212897.html