Multi-Shot DWI of the Breast with MUSE and shot-LLR Reconstructions
This manuscript presents a clinical breast MRI study that investigates the performance of single-shot DWI and multi-shot DWI reconstructed by two different techniques (MUSE and Shot-LLR). Our results demonstrate that both two multi-shot DWI methods provide improved performance in comparison to single-shot DWI in the breast in terms of general image quality and depiction of lesions. The advantages of increasing the number of shots with multi-shot DWI in the breast are also delineated with perceived SNR and perceived resolution that improves with 8 versus 4 shots. In particular the superior performance of shot-LLR compared to MUSE for resolving shot-to-shot ghosting artifacts may be advantageous for wide clinical implementation of the method. Finally, these results support that the continued refinement of advanced DWI methods may facilitate implementation of a non-contrast-enhanced screening breast MRI protocol.
Hu Y, Ikeda DM, Pittman SM, Samarawickrama D, Guidon A, Rosenberg J, Chen S, Okamoto S, Daniel BL, Hargreaves BA, Moran CJ. Multishot Diffusion-Weighted MRI of the Breast With Multiplexed Sensitivity Encoding (MUSE) and Shot Locally Low-Rank (Shot-LLR) Reconstructions. J Magn Reson Imaging. 2020 Oct 16. doi: 10.1002/jmri.27383. Online ahead of print.