Fat-Based Registration of Breast Dynamic Contrast Enhanced Water Images
Dynamic contrast-enhanced breast MRI scans take 5-10 minutes to acquire, so motion between the temporal phases is a common problem that must be corrected before post-processing. This paper proposes a new technique to register the images and correct for motion using Dixon-based fat- and water-separated images. Because the fat signal does not change over time, the fat images can be used to determine the registration that should then be applied to correct the water images, which are the ones of true clinical interest.
Srinivasan S, Hargreaves BA, Daniel BL. Fat-based registration of breast dynamic contrast enhanced water images. Magn Reson Med. 2018 Apr;79(4):2408-14.
Water-based image registration introduces new motion across phases (yellow arrows), which is not introduced using fat-based image registration instead. Cardiac flow artifacts are similar in the original and fat-based registered images, but are reduced in the water-based registered images.
Subashini Srinivasan is an alumnus of the BMR group