Post-Translational Regulation of Clcnkb
Post-Translational Regulation of Clckb
A major regulator of sodium reabsorption, Clcnkb, is mutated in humans with Barrter's syndrome, Type 3. However, surprisingly little is known about the regulation of this channel in health and disease. Ongoing experiments include the study of post-translational regulation of Clcnkb surface expression and activity using in vitro and in vivo approaches.