News From our Center

Publication highlight: Parallelized Immunomagnetic Isolation of Basophils Directly from Whole Blood

Basophils are one of the key immune cells responsible for allergic reactions, and several studies have identified markers on basophils that are associated with improved oral immunotherapy outcomes in food allergy. However, the low abundance of basophils in the blood has made them hard to study and isolate, limiting their clinical utility.

December 3, 2023

Publication highlight: The Role of Biologics in the Treatment of Food Allergy

Biological therapeutics (biologics) including antibodies targeting allergic pathways have shown promising potential for the treatment of food allergy. However, there are many questions that need to be addressed before they see widespread use in clinical practice.

November 25, 2023

Highlights from PAAM Hybrid Conference: Biologics in food allergy

At the recent international Pediatric Allergy and Asthma Meeting (PAAM) held annually by the European Academy of Allergy and Clinical Immunology (EAACI), Sayantani (Tina) Sindher discussed the use of biologics for treating food allergy in children.

November 3, 2023

Publication highlight: Oral Immunotherapy for Peanut Allergy in Children 1 to Less Than 4 Years of Age

Oral immunotherapy has proven to be safe and effective for treating food allergies, and prior studies have suggested that higher clinical benefits are seen in younger individuals. However, how young can oral immunotherapy be safely introduced?

October 23, 2023

Highlights from Global Food Allergy Prevention Summit 2023: Early Treatment and Secondary Prevention of Food Allergy with Biologics

The Global Food Allergy Prevention Summit brings together international leaders in food allergy research to discuss the future of food allergy prevention. This year Dr. Sharon Chinthrajah discussed the use of biologics for the treatment and prevention of food allergy.

July 8, 2023

Highlights from Global Food Allergy Prevention Summit 2023: Early Oral Immunotherapy (OIT)

Another exciting talk at the Global Food Allergy Prevention Summit 2023 was Sayantani (Tina) Sindher’s discussion on early oral immunotherapy (OIT). OIT has proven to be safe and effective for the treatment of food allergy, however when should treatment be initiated?

July 7, 2023

Publication highlight: Treatment of food allergy: Oral immunotherapy, biologics, and beyond

Although oral immunotherapy is effective at treating food allergy, it has several limitations which include a slow time-frame, frequent although mostly mild adverse reactions, and patient anxiety. Increasing efforts are being placed on the study of biological therapeutics which target the underlying disease mechanisms of allergy which could not only improve the safety and effectiveness of oral immunotherapy, but also have the potential for the treatment of food allergy by themselves.

April 25, 2023

Highlights from The British Society for Allergy & Clinical Immunology (BSACI) Global Allergy Online Symposium: Conversations with patients about oral immunotherapy

At the recent international BSACI Global Allergy Online Symposium, Dr. Sharon Chinthrajah and Dr. Sayantani Sindher shared their discussions with patients who were interested in oral immunotherapy for food allergy. The decision to initiate oral immunotherapy is made after careful shared-decision making discussions between physicians, patients, and their families.

February 10, 2023

Publication highlight: Transitioning from epicutaneous to oral peanut immunotherapy

Epicutaneous immunotherapy (EPIT) is a food allergy immunotherapy strategy that uses a skin patch to train the immune system to tolerate food allergens. In comparison to the more widely used oral immunotherapy (OIT), EPIT is generally considered to be safer but provides less protection than OIT.

February 6, 2023

Publication highlight: Retail Food Equivalents for Post-Oral Immunotherapy Dosing in the Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen Oral Immunotherapy in Food-Allergic Children and Adults (OUtMATCH) Clinical Trial

After the completion of oral immunotherapy or other immunotherapy strategies for food allergy, food allergic individuals are often advised to introduce small amounts of specific foods into their diet, however retail foods have different amounts of allergens than the doses they received during oral immunotherapy. So how much should they consume?

February 1, 2023


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