Stanford ADRC Publications

2018

Askari N, Bilbrey AC, Garcia Ruiz I, Humber MB, Gallagher-Thompson D.  Dementia awareness campaign in the Latino community: a novel community engagement pilot program with promotoras. Clinical Gerontologist. 2018;41(3):200-208. PMID:29240536; PMCID: PMC5935246.

Bagge CN, Henderson VW, Laursen HB, Adelborg K, Olsen M, Madsen NL. Risk of dementia in adults with congenital heart disease: Population-based cohort study. Circulation. 2018;137(2):1912-1920. PMID: 29440121; PMCID: PMC5930034.

Barnes J, Bartlett JW, Wolk DA, van der Flier WM, Frost C. Disease course varies according to age and symptom length in Alzheimer’s disease. Journal of Alzheimer’s Disease. 2018;64(2):631-642. PMID: 29914016; PMCID: PMC6207933.

Bennett FC, Bennett ML, Yaqoob F, Mulinyawe SB, Grant GA, Hayden GM, Plowey ED, Barres BA. A Combination of ontogeny and CNS environment establishes microglial identity. Neuron. 2018;98(6) :1170-1183.e8. PMID: 29861285; PMCID: PMC6023731. 

Bharadwaj R, Cimino PJ, Flanagan ME, Latimer CS, Gonzalez-Cuyar LF, Juric-Sekhar G, Montine TJ, Marshall DA, Keene CD. Application of the condensed protocol for the NIA-AA guidelines for the neuropathological assessment of Alzheimer’s disease in an academic clinical practice. Histopathology. 2018;72(3):433-440. PMID: 28815699; PMCID: PMC5771846.

Bilbrey AC, Humber MB, Plowey ED, Garcia I, Chennapragada L, Desai K, Rosen A, Askari N, Gallagher-Thompson D.  The impact of Latino values and cultural beliefs on brain donation: Results of a pilot study to develop culturally appropriate materials and methods to increase rates of brain donation in this under-studied patient group. Clinical Gerontologist. 2018;41(3):237-248. PMID: 29227743; PMCID: PMC5962259.

Brenowitz WD, Han F, Kukull WA, Nelson PT. Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults. Neurobiology of Aging. 2018 02; 62 :64-71. PMID: 29107848: PMCID: PMC5743774. 

Burke SL, Cadet T, Maddux M. Chronic health illnesses as predictors of mild cognitive impairment among African American older adults. Journal of the National Medical Association. 2018;110(4):314-325. PMID: 30126555; PMCID: PMC6108440.

Burke SL, Hu T, Fava NM, Li T, Rodriguez MJ, Schuldiner KL, Burgess A, Laird A. Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities. Journal of Women & Aging. 2018:1-25. PMID: 29319430; PMCID: PMC6039284.

Burke SL, Maramaldi P, Cadet T, Kukull W. Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E.  International Journal of Geriatric Psychiatry. 2018;33(1):200-211. PMID: 28560728; PMCID: PMC5711617.

Clark, JL; Phoenix S, Bilbrey, AC; McManis, T, Escal KA, Arulanantham R, Sisay T, Ghatak R. Cultural Competency in dementia care: An African American case study. Clinical Gerontologist. 2018;41(3):255-260. PMID: 29338663; PMCID: PMC5962259. 

Cocoros NM, Ording AG, Horváth-Puhó E, Henderson VW, Sørensen HT. In utero exposure to the 1918 pandemic influenza in Denmark and risk of dementia. Influenza and Other Respiratory Viruses. 2018;12(3):314-318. PMID: 29356338; PMCID: PMC5907820.

Crum J, Wilson J, Sabbagh M. Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer’s dementia? Alzheimer’s Research & Therapy. 2018;10(1):104. PMID: 30285877; PMCID: PMC6169006.

Flanagan, ME, Keene CD, Louis DN, Juric‐Sekhar G. Localized crystal-storing histiocytosis of the posterior fossa.  Neuropathology. 2018;38(5):529-534. PMID: 30066398; PMCID: PMC 6172157.

Flanagan ME, Larson EB, Walker RL, Keene CD, Postupna N, Cholerton B, Sonnen JA, Dublin S, Crane PK, Montine TJ. Associations between use of specific analgesics and concentrations of amyloid-β 42 or phospho-tau in regions of human cerebral cortex. Journal of Alzheimer’s Disease. 2018;61(2):653-662. PMID: 29226863; PMCID: PMC5745256.

Gallagher D, Kiss A, Lanctot K, Herrmann, N.  Depression and risk of Alzheimer dementia: A longitudinal analysis to determine predictors of increased risk among older adults with depression. American Journal of Geriatric Psychiatry. 2018;26(8):819-827. PMID: 29960668; PMCID: PMC6101977.

Ge T, Sabuncu MR, Smoller JW, Sperling RA, Mormino EC; Alzheimer's Disease Neuroimaging Initiative. Dissociable influences of ApoE ε4 and polygenic risk of AD dementia on amyloid and cognition. Neurology. 2018;90(18):e1605-e1612. PMID: 29592889; PMCID: PMC5931806.

Haaksma ML, Calderón-Larrañaga A, Olde R, Marcel GM; Melis RJF, Leoutsakos JMS. Cognitive and functional progression in Alzheimer’s disease: a prediction model of latent classes. International Journal of Geriatric Psychiatry. 2018;33(8):1057-1064.  PMID: 29761569: PMCID: PMC6039270.

Hadjichrysanthou C, McRae-McKee K, Evans S, de Wolf F, Anderson RM; Alzheimer’s Disease Neuroimaging Initiative. Potential factors associated with cognitive improvement of individuals diagnosed with mild cognitive impairment or dementia in longitudinal studies. Journal of Alzheimer’s Disease. 2018;66(2):587-600. PMID: 30320573; PMCID: PMC6218131.

Hanfelt JJ, Peng L, Goldstein FC, Lah JJ. Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: analysis of data from the National Alzheimer's Coordinating Center. Neurobiology of Disease. 2018;117:62-71. PMC: 29859866; PMCID: PMC6093304.

Harvey ZH, Chen Y, Jarosz DF. Protein-based inheritance: Epigenetics beyond the chromosome. Molecular Cell. 2018;69(2):195-202. PMID: 29153393; PMCID: PMC5775936.

Kamara DM, Gangishetti U, Gearing M, Willis-Parker M, Zhao L, Hu WT, Walker LC. Cerebral amyloid angiopathy: Similarity in African-Americans and Caucasians with Alzheimer’s disease. Journal of Alzheimer’s disease. 2018:62(4):1815-1826. PMID: 29614657; PMCID: PMC6103628.

Kaur A, Edland SD, Peavy GM. The MoCA-memory index score: an efficient alternative to paragraph recall for the detection of amnestic mild cognitive impairment. Alzheimer Disease and Associated Disorders. 2018;32(2):120-124. PMID: 29319601; PMCID: PMC5963962.

Kirson NY, Scott Andrews J, Desai U, King SB, Schonfeld S, Birnbaum HG, Ball DE, Kahle-Wrobleski K. Patient characteristics and outcomes associated with receiving an earlier versus later diagnosis of probable Alzheimer’s disease. Journal of Alzheimer’s Disease. 2018;61(1):295-307. PMID:29154268; PMCID: PMC5734126.

Lin, M, Gong, P, Yang, T, Ye, J, Albin, RL, Dodge, HH. Big data analytical approaches to the NACC dataset: aiding preclinical trial enrichment. Alzheimer Disease and Associated Disorders. 2018;32(1):18-27. PMID: 29227306; PMCID: PMC5854492.

Qiu S, Chang GH, Panagia M, Gopal DM, Au R, Kolachalama VB. Fusion of deep learning models of MRI scans, Mini-Mental State Examination, and logical memory test enhances diagnosis of mild cognitive impairment. Alzheimer’s & Dementia. 2018;10:737-749. PMID: 30480079; PMCID: PMC6240705.

Schaffert J, LoBue C, White CL, Chiang HS, Didehbani N, Lacritz L, Rossetti H, Dieppa M, Hart J, Cullum CM.  Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer's disease. Neuropsychology. 2018:32(4):410-416. PMID:29389151; PMCID: PMC5975092.

Sclesi MA, Khan RR, Lorenzi M, Chrisopher L, Greicius MD, Schott JM, Ourselin S, Altmann A: Genetic study of multimodal imaging Alzheimer’s disease progression score implicates novel loci. Brain. 2018; 141:2167-2180. PMID:29860282; PMCID: PMC6022660.

Smith AK, Periyakoil VS. Should we bury "The Good Death"?  Journal of the American Geriatrics Society. 2018;66(5):856-858. PMID: 29508391; PMCID: PMC5992042.

Svensson E, Henderson VW, Szépligeti S, Stokholm MG, Klug TE, Sørensen HT, Borghammer P. Tonsillectomy and risk of Parkinson ‘s disease: a Danish nationwide population-based cohort study. Movement Disorders. 2018;33(2):321-324. PMID: 29193401; PMCID: PMC5809198.

Ting SKS, Foo H, Chia PS, Hameed S, Ng KP, Ng A, Kandiah N.  Dyslexic characteristics of Chinese-speaking semantic variant of primary progressive aphasia. Journal of Neuropsychiatry and Clinical Neurosciences. 2018;30(1):31-37. PMID: 29061089; PMCID: PMC5794526.

Tse KH, Cheng A, Ma F, Herrup K. DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia. Alzheimer's & Dementia. 2018;14(5):664-679.  PMID:29328926; PMCID: PMC5938117.  

Turk KW, Flanagan ME, Josephson S, Keene CD, Jayadev S, Bird TD. Psychosis in spinocerebellar ataxias: a case series and study of tyrosine hydroxylase in substantia nigra. Cerebellum. 2018;17(2):143-151. PMID: 28887803; PMCID: PMC5843512.

Wang T, Qiu RG,Yu M.  Predictive modeling of the progression of Alzheimer’s disease with recurrent neural networks. Scientific Reports. 2018;8(1):9161. PMC: 29907747; PMCID: PMC6003986.

Weintraub S, Besser L, Dodge HH, Teylan M, Ferris S, Goldstein FC, Giordani B, Kramer J, Loewenstein D, Marson D, Mungas D, Salmon D, Welsh-Bohmer K, Zhou XH, Shirk SD, Atri A, Kukull WA, Phelps C, Morris JC. Version 3 of the Alzheimer Disease Centers & ApoE neuropsychological test battery in the Uniform Data Set (UDS). Alzheimer Disease and Associated Disorders. 2018;32(1):10-17. PMID: 29240561; PMCID: PMC5821520.

Wilmoth K, LoBue C, Clem MA, Reddy R, Hynan LS, Didehbani N, Bell K, Womack KB, Hart Jr J, Batjer H, Cullum CM.  Consistency of traumatic brain injury reporting in older adults with and without cognitive impairment.  Clinical Neuropsychologist. 2018;32(3):524-529. PMID: 28988512; PMCID: PMC5851823.

2017

Adelborg K, Horváth-Puhó E, Ording A, Pedersen L, Toft Sørensen H, Henderson VW. Heart failure and risk of dementia: a Danish nationwide population-based cohort study. European Journal of Heart Failure. 2017;19(2):253-260. PMID: 27612177; PMCID: PMC5522185.

Beaudreau SA, Hantke NC, Mashal N, Gould CE, Henderson VW, O'Hara, R. Unlocking neurocognitive substrates of late-life affective symptoms using the research domain criteria: worry is an essential dimension. Frontiers of Aging Neuroscience. 2017;9:380. PMID: 29249958; PMCID: PMC5715397.

Bernier PJ, Gourdeau C, Carmichael PH, Beauchemin JP, Verreault R,  Bouchard RW, Kröger E, Laforce Jr R. Validation and diagnostic accuracy of predictive curves of age-associated longitudinal cognitive decline in older adults. Canadian Medical Association journal. 2017;189(48):E1472-E1480. PMID: 29203616; PMCID: PMC5714699.

Boise L, Hinton L, Rosen HJ, Ruhl MC, Dodge H, Mattek N, Albert M, Denny A, Grill JD, Hughes T, Lingler JH, Morhardt D, Parfitt F, Peterson-Hazan S, Pop V, Rose T, Shah RC. Willingness to be a brain donor: a survey of research volunteers from 4 racial/ethnic groups. Alzheimer Disease and Associated Disorders. 2017;31(2):135-140. PMID: 27779492; PMCID: PMC5403614.

Brenowitz WD, Hubbard RA, Keene CD, Hawes SE, Longstreth WT Jr, Woltjer RL, Kukull WA. Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample. Alzheimer’s Dement. 2017;13(6):654-662. PMID: 27870939; PMCID: PMC5438283.

Brenowitz WD, Keene CD, Hawes SE, Hubbard RA, Longstreth WT Jr., Woltjer RL, Crane PK, Larson EB, Kukull WA. Alzheimer’s disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples. Neurobiology of Aging. 2017;53:83-92. PMID: 28236716; PMCID: PMC5385292.

Burke SL, O'Driscoll J, Alcide A, Li T. Moderating risk of Alzheimer's disease through the use of anxiolytic agents. International Journal of Geriatric Psychiatry. 2017;32(12):1312-1321. PMID: 27805724; PMCID: PMC5441966.

Castellano JM, Mosher KI, Abbey RJ, McBride AA, James ML, Berdnik D, Shen JC, Zou B, Xie XS, Tingle M, Hinkson IV, Angst MS, Wyss-Coray T. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature. 2017;544(7651):488-492. PMID: 28424512; PMCID: PMC5586222.

Christopher L, Napolioni V, Khan RR, Han SS, Greicius MD. A variant in PPP4R3A protects against Alzheimer-related metabolic decline. Annals of Neurology. 2017;82(6):900-911. PMID: 29130521; PMCID: PMC5752155.

Corces MR, Trevino AE, Hamilton EG, Greenside PG, Sinnott-Armstrong NA, Vesuna S, Satpathy AT, Rubin AJ, Montine KS, Wu B, Kathiria A, Cho SW, Mumbach MR, Carter AC, Kasowski M, Orloff LA, Risca VI, Kundaje A, Khavari PA, Montine TJ, Greenleaf WJ, Chang HY. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nature Methods. 2017;14(10):959-962. PMID: 28846090; PMCID: PMC5623106.

Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, Wyss-Coray T. Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity. Journal of Experimental Medicine. 2017;214(4):1081-1092. PMID: 28298456; PMCID: PMC5379986.

Flanagan ME, Marshall DA, Shofer JB, Montine KS, Nelson PT, Montine TJ, Keene CD. Performance of a condensed protocol that reduces effort and cost of NIA-AA guidelines for neuropathologic assessment of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 2017;76(1):39-43. PMID: 28062571; PMCID: PMC6251587.

Goldstein FC, Steenland K, Zhao L, Wharton W, Levey AI, Hajjar I. Proton pump inhibitors and risk of mild cognitive impairment and dementia. Journal of the American Geriatrics Society. 2017;65(9):1969-1974.  PMID: 28590010; PMCID: PMC5797939.

Hendershott TR, Zhu D, Llanes S, Poston KL. Domain-specific accuracy of the Montreal cognitive assessment subsections in Parkinson’s disease. Parkinsonism & Related Disorders. 2017:38:31-34. PMID: 28215728; PMCID: PMC5400012.

Jefferson-George KS, Wolk DA, Lee EB, McMillan CT. Cognitive decline associated with pathological burden in primary age-related tauopathy. Alzheimer’s & Dementia. 2017;13(9):1048-1053. PMID: 28322204; PMCID: PMC5585025.

Jutkowitz E, Kane RL, Gaugler JE, MacLehose RF, Dowd B, Kuntz KM. Societal and family lifetime cost of dementia: implications for policy. Journal of the American Geriatrics Society. 2017;65(10):2169-2175. PMID: 28815557; PMCID: PMC5657516.

Jutkowitz E, MacLehose RF, Gaugler JE, Dowd B, Kuntz KM, Kane RL. Risk factors associated with cognitive, functional, and behavioral trajectories of newly diagnosed dementia patients. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2017;72(2):251-258. PMID: 27129917; PMCID: PMC5344797.

Katsumata Y, Nelson PT, Ellingson SR, Fardo DW. Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2. Neurobiology of Aging. 2017;53:193.e17-193.e25. PMID: 28131462; PMCID: PMC5385271.

Kim J, Schweizer TA, Fischer CE, Munoz DG. The role of cerebrovascular disease on cognitive and functional status and psychosis in severe Alzheimer’s disease. Journal of Alzheimer & ApoE disease. 2017;55(1):381-389. PMID: 27662301; PMCID: PMC5115606.

Lange C, Suppa P,  Mäurer A, Ritter K, Pietrzyk U, Steinhagen-Thiessen E,  Fiebach JB, Spies L, Buchert R. Mental speed is associated with the shape irregularity of white matter MRI hyperintensity load. Brain Imaging and Behavior. 2017;11(6):1720-1730. PMID: 27796731; PMCID: PMC5843991.

Latimer CS, Keene CD, Flanagan ME, Hemmy LS, Lim KO, White LR, Montine KS, Montine TJ. Resistance to Alzheimer disease neuropathologic changes and apparent cognitive resilience in the nun and Honolulu-Asia aging studies. Journal of Neuropathology and Experimental Neurology. 2017;76(6):458-466. PMID: 28499012.

Lim YY, Mormino EC; Alzheimer's Disease Neuroimaging Initiative. ApoE genotype and early β-amyloid accumulation in older adults without dementia. Neurology. 2017;89(10):1028-1034. PMID: 28794245; PMCID: PMC5589795.

Mathur V, Burai R, Vest RT, Bonanno LN, Lehallier B, Zardeneta ME, Mistry KN, Do D, Marsh SE, Abud EM, Blurton-Jones M, Li L, Lashuel HA, Wyss-Coray T. Activation of the STING-dependent Type I interferon response reduces microglial reactivity and neuroinflammation. Neuron. 2017;96(6):1290-1302.e6. PMID: 29268096; PMCID: PMC5806703.

Moga DC, Taipale H, Tolppanen AM, Tanskanen A, Tiihonen J, Hartikainen S, Wu Q, Jicha GA, Gnjidic D. A comparison of sex differences in psychotropic medication use in older people with Alzheimer’s disease in the US and Finland. Drugs & Aging. 2017;34(1):55-65. PMID: 27896799; PMCID: PMC5253689.

Moga DC, Abner EL, Wu Q, Jicha GA. Bladder antimuscarinics and cognitive decline in elderly patients. Alzheimer’s & Dementia. 2017;3(1):139-148. PMID: 28462390; PMCID: PMC5408467.

Moheb N, Mendez MF, Kremen SA, Teng E. Executive dysfunction and behavioral symptoms are associated with deficits in instrumental activities of daily living in frontotemporal dementia. Dementia and Geriatric Cognitive Disorders. 2017;43(1-2):89-99. PMID: 28103593; PMCID: PMC5300022.

Montgomery V, Harris K, Stabler A, Lu LH. Effects of delay duration on the WMS logical memory performance of older adults with probable Alzheimer’s disease, probable vascular dementia, and normal cognition. Archives of Clinical Neuropsychology. 2017;32(3):375-380. PMID: 28431036; PMCID: PMC5400025.

Neu SC, Pa J, Kukull W, Beekly D, Kuzma A, Gangadharan P, Wang LS, Romero K, Arneric SP, Redolfi A, Orlandi D, Frisoni GB, Au R, Devine S, Auerbach S, Espinosa A, Boada M, Ruiz A, Johnson SC, Koscik R, Wang JJ, Hsu WC, Chen YL, Toga AW. Apolipoprotein E genotype and sex risk factors for Alzheimer disease: a meta-analysis. JAMA Neurology. 2017;74(10):1178-1189. PMID: 28846757; PMCID: PMC5759346.

Ng B, Varoquaux G, Poline JB, Thirion B, Greicius MD, Poston KL. Distinct alterations in Parkinson’s medication-state and disease-state connectivity. NeuroImage. Clinical. 2017;16:575-585. PMID: 28971008; PMCID: PMC5608603.

Pandya SY, Lacritz LH, Weiner MF, Deschner M, Woon FL. Predictors of reversion from mild cognitive impairment to normal cognition. Dementia and Geriatric Cognitive Disorders. 2017;43(3-4):204-214. PMID: 28301848; PMCID: PMC5495561.

Postupna N, Latimer CS, Larson EB, Sherfield E, Paladin J, Shively CA, Jorgensen MJ, Andrews RN, Kaplan JR, Crane PK, Montine KS, Craft S, Keene CD, Montine TJ. Human striatal dopaminergic and regional serotonergic synaptic degeneration with Lewy Body Disease and inheritance of APOE ε4. American Journal of Pathology. 2017;187(4): 884-895. PMID: 28212814; PMCID: PMC5397713.

Ramsey CM, Gnjidic D, Agogo GO, Allore H, Moga D. Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis. Alzheimer’s & Dementia. 2017;4:1-10. PMID: 29296658; PMCID: PMC5738721.

Ritter AR, Leger GC, Miller JB, Banks SJ. Neuropsychological testing in pathologically verified Alzheimer disease and frontotemporal dementia: How well do the Uniform Data Set measures differentiate between diseases?  Alzheimer Disease and Associated Disorders. 2017;31(3):187-191. PMID: 28005562; PMCID: PMC5479762.

Sano M, Zhu CW, Grossman H, Schimming C. Longitudinal cognitive profiles in diabetes: results from the National Alzheimer's Coordinating Center's Uniform Data. Journal of the American Geriatrics Society. 2017;65(10):2198-2204. PMID: 28771679; PMCID: PMC5641239.

Schmidt SA, Ording AG, Horváth-Puhó E, Sørensen HT, Henderson VW. Non- melanoma skin cancer and risk of Alzheimer’s disease and all-cause dementia. PloS ONE. 2017;12(2): e0171527. PMID: 28225789; PMCID: PMC5321271.

Sennik S, Schweizer TA, Fischer CE, Munoz DG. Risk factors and pathological substrates associated with agitation/aggression in Alzheimer’s disease: A preliminary study using NACC data. Journal of Alzheimer’s Disease. 2017;55(4):1519-1528. PMID: 27911311; PMCID: PMC5607738.

Tchakoute CT, Sainani KL, Henderson VW. Semantic memory in the clinical progression of Alzheimer disease. Cognitive and Behavioral Neurology. 2017;30(3):81-89. PMID: 28926415; PMCID: PMC5617354.

Tripodis Y, Alosco ML, Zirogiannis N, Gavett BE, Chaisson C, Martin B, McClean MD, Mez J, Kowall N, Stern RA. The effect of traumatic brain injury history with loss of consciousness on rate of cognitive decline among older adults with normal cognition and Alzheimer’s disease dementia. Journal of Alzheimer's Disease. 2017;59(1):251-263. PMID: 28655133; PMCID: PMC5614490.

Qian J, Hyman BT, Betensky RA. Neurofibrillary tangle stage and the rate of progression of Alzheimer symptoms: modeling using an autopsy cohort and application to clinical trial design. JAMA Neurology. 2017;74(5):540-548. PMID: 28288263; PMCID: PMC5547572.

2016

Andreasson KI, Bachstetter AD, Colonna M, Ginhoux F, Holmes C, Lamb B, Landreth G, Lee DC, Low D, Lynch MA, Monsonego A, O’Banion MK, Pekny M, Puschmann T, Russek-Blum N, Sandusky LA, Selenica ML, Takata K, Teeling J, Town T, Van Eldik LJ. Targeting innate immunity for neurodegenerative disorders of the nervous system. Journal of Neurochemistry. 2016; 138(5):653-93. PMID: 27248001; PMCID: PMC5433264.

Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS. Age-dependent effects of APOE ε4 in preclinical Alzheimer’s disease. Annals of Clinical and Translational Neurology. 2016;3(9):668-77. PMID: 27648456; PMCID: PMC5018579.

Burke SL, Maramaldi P, Cadet T, Kukull W. Neuropsychiatric symptoms and Apolipoprotein E: associations with eventual Alzheimer’s disease development. Archives of Gerontology and Geriatrics. 2016;65:231-8. PMID: 27111252; PMCID: PMC5029123.

Day GS, Musiek ES, Roe CM, Norton J, Goate AM, Cruchaga C, Cairns NJ, Morris JC. Phenotypic similarities between late-onset autosomal dominant and sporadic Alzheimer disease: a single-family case-control study. JAMA Neurology. 2016;73(9):1125-32. PMID: 27454811; PMCID: PMC5025942.

Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. Cognitive effects of estradiol after menopause: a randomized trial of the timing hypothesis. Neurology. 2016;87(7):699-708. PMID: 27421538; PMCID: PMC4999165.

Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T. Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain. Molecular Neurodegeneration. 2016;11:31. PMID: 27112350; PMCID: PMC4845325.

Karim R, Dang H, Henderson VW, Hodis HN, St John J, Brinton RD, Mack WJ. Effect of reproductive history and exogenous hormone use on cognitive function in mid- and late life. Journal of the American Geriatrics Society. 2016;64(12):2448- 2456. PMID: 27996108; PMCID: PMC5180359.

Middeldorp J, Lehallier B, Villeda SA, Miedema SS, Evans E, Czirr E, Zhang H, Luo J, Stan T, Mosher KI, Masliah E, Wyss-Coray T. Preclinical assessment of young blood plasma for Alzheimer disease. JAMA Neurology. 2016;73(11):1325-1333. PMID: 27598869; PMCID: PMC5172595.

Nead KT, Gaskin G, Chester C, Swisher-McClure S, Dudley JT, Leeper NJ, Shah NH. Androgen deprivation therapy and future Alzheimer’s disease risk. Journal of Clinical Oncology. 2016;34(6):566-71. PMID: 26644522; PMCID: PMC5070576.

Nead KT, Gaskin G, Chester C, Swisher-McClure S, Dudley JT, Leeper NJ, Shah NH. Influence of age on androgen deprivation therapy-associated Alzheimer’s disease. Scientific Reports. 2016;6:35695. PMID: 27752112; PMCID: PMC5067668.

Plowey ED, Ziskin JL. Hippocampal phospho-tau/MAPT neuropathology in the fornix in Alzheimer disease: an immunohistochemical autopsy study. Acta Neuropathologica Communications. 2016;4(1):114. PMID: 27793193; PMCID: PMC5086039.

Poston KL, YorkWilliams S, Zhang K, Cai W, Everling D, Tayim FM, Llanes S, Menon V. Compensatory neural mechanisms in cognitively unimpaired Parkinson disease. Annals of Neurology. 2016;79(3):448-63. PMID: 26696272; PMCID: PMC4789131.

Rettberg JR, Dang H, Hodis HN, Henderson VW, St John JA, Mack WJ, Brinton RD. Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer’s risk metabolic phenotype. Neurobiology of Aging. 2016;40:155-63. PMID: 26973115; PMCID: PMC4921204.

Simmons DA, Belichenko NP, Ford EC, Semaan S, Monbureau M, Aiyaswamy S, Holman CM, Condon C, Shamloo M, Massa SM, Longo FM. A small molecule p75NTR ligand normalizes signaling and reduces Huntington’s disease phenotypes in R6/2 and BACHD mice. Human Molecular Genetics. 2016;25(22):4920- 4938. PMID: 28171570; PMCID: PMC5418739.

Warden C, Hwang J, Marshall A, Fenesy M, Poston KL. The effects of dopamine on digit span in Parkinson’s disease. Journal of Clinical Movement Disorders. 2016;3:5. PMID: 26955482; PMCID: PMC4780147.

Woodling NS, Andreasson KI. Untangling the web: Toxic and protective effects of neuroinflammation and PGE2 signaling in Alzheimer’s disease. ACS Chemical Neuroscience. 2016;7(4):454-63. PMID: 26979823; PMCID: PMC5239037.

Woodling NS, Colas D, Wang Q, Minhas P, Panchal M, Liang X, Mhatre SD, Brown H, Ko N, Zagol-Ikapitte I, van der Hart M, Khroyan TV, Chuluun B, Priyam PG, Milne GL, Rassoulpour A, Boutaud O, Manning-Boğ AB, Heller HC, Andreasson KI. Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer’s disease model mice. Brain. 2016;139(Pt 7):2063-81. PMID: 27190010; PMCID: PMC4939702.

Wyss-Coray T. Ageing, neurodegeneration and brain rejuvenation. Nature. 2016;539(7628):180-186. PMID: 27830812; PMCID: PMC517260.

2015

Leaver K, Poston KL. Do CSF biomarkers predict progression to cognitive impairment in Parkinson‘s disease patients? a systematic review. Neuropsychology Review. 2015;25(4):411-23. PMID: 26626621; PMCID: PMC5152566.

Lehallier B, Essioux L, Gayan J, Alexandridis R, Nikolcheva T, Wyss-Coray T, Britschgi M. Combined plasma and cerebrospinal fluid signature for the prediction of midterm progression from mild cognitive impairment to Alzheimer disease. JAMA Neurology. 2015;1-10. PMID: 26659895; PMCID: PMC5214993.

Lehert P, Villaseca P, Hogervorst E, Maki PM, Henderson VW. Individually modifiable risk factors to ameliorate cognitive aging: a systematic review and meta-analysis. Climacteric. 2015;18(5):678-89. PMID: 26361790; PMCID: PMC5199766.

Müller-Oehring EM, Sullivan EV, Pfefferbaum A, Huang NC, Poston KL, Bronte-Stewart HM, Schulte T. Task-rest modulation of basal ganglia connectivity in mild to moderate Parkinson’s disease. Brain Imaging and Behavior. 2015;9(3):619-38. PMID: 25280970; PMCID: PMC4385510.