Stanford ADRC Administrative Core

The vision of the Stanford Alzheimer’s Disease Research Center (ADRC) is to serve at the forefront of the national effort to prevent dementia due to Alzheimer’s disease and related disorders and to find effective forms treatment. Its mission is to serve as a shared resource to facilitate and enhance multidisciplinary and interdisciplinary research, outreach, and education in Alzheimer’s disease, Parkinson’s disease and related disorders. The ADRC mission extends to milder forms cognitive impairment and encompasses healthy brain aging. 

The leadership team works through the ADRC Executive Committee to provide administrative oversight for all Center activities. Key personnel are Victor Henderson (director), Tony Wyss-Coray (co-director), Frank Longo (associate director), and Jerome Yesavage (associate director). Nusha Askari is the senior administrator, Emiko Miyamoto is ADRC financial analyst, Beth Hoyte is the web administrator, and Falene Garcia is the administrative associate.

Victor W. Henderson, MD, MS
Professor of Health Research and Policy
Professor of Neurology and Neurological Sciences
ADRC Director

Dr. Henderson directs the Stanford ADRC and co-directs the Stanford master degree program in epidemiology and clinical research. His research interests in the areas of geriatric neurology and neuroepidemiology emphasize risk factors for cognitive aging, Alzheimer’s disease and related disorders, and therapeutic strategies to maintain and improve cognitive abilities affected by cognitive aging or dementia. Dr. Henderson obtained his medical degree from Johns Hopkins University and master degree in epidemiology from the University of Washington School of Public Health. He trained at Duke University (internal medicine), Washington University (neurology), and Boston University (behavioral neurology). He has been a visiting scientist at the Massachusetts Institute of Technology, visiting professor at the University of Melbourne (Australia), and is an honorary professor at the University of Aarhus (Denmark). He has served in leadership roles concerned with late-life cognitive disorders (chair of the Geriatric Neurology Section of the American Academy of Neurology) and midlife cognitive health (president of the North American Menopause Society; general secretary of the International Menopause Society). He serves on editorial boards and scientific advisory boards, and he has authored more than 200 scientific articles and chapters.

Tony Wyss-Coray, PhD
Professor of Neurology and Neurological Sciences
ADRC Co-Director

The Wyss-Coray laboratory seeks to understand how immune responses and systemic aging affect the brain and may contribute to neurodegeneration and Alzheimer’s disease. Over the past few years the lab has been particularly intrigued by the observation that brain aging can be altered by changes in the systemic environment and we have shown that blood-derived factors are sufficient to modulate brain physiology at the molecular, cellular, and functional level. We have developed focused proteomic tools to measure hundreds of secreted signaling proteins with the goal to identify key factors involved in brain aging and neurodegeneration.

Frank M. Longo, MD, PhD
George E. and Lucy Becker Professor in Medicine Professor of Neurology and Neurological Sciences
ADRC Associate Director

Dr. Longo is chair of the Department of Neurology and Neurological Sciences and directs the Stanford Alzheimer’s Translational Research Center. His clinical interest include Alzheimer’s disease and other neurodegenerative disorders.  His research team is developing new drugs that are focused on the modulation of fundamental cell signaling pathways that are involved in neurodegeneration. These pathways can be regulated by known protein growth factors but such proteins cannot be used as drugs. Dr. Longo’s team has pioneered the development of the first small molecule, drug-type compounds that can mimic key parts of growth factor proteins and achieve their potent effects on preventing or reversing degeneration. Work in Alzheimer’s mice has been extremely promising and efforts are now underway to bring the first of these compounds to human trials.

Jerome Yesavage, MD
Professor of Psychiatry and Behavioral Sciences
Professor of Neurology and Neurological Sciences (by courtesy)
ADRC Associate Director

Dr. Yesavage is Associate Chair of Psychiatry and Behavioral Sciences andAssociate Chief of Staff for Mental Health at the VA Palo Alto Health Care system, where he directs the Mental Illness Research Educational and Clinical Center (MIRECC).  His MIRECC and NIH research has focused on behavioral disturbances of late life with an emphasis of the Vietnam Era Veteran.

Currently these activities include studies of geriatric depression and treatment with repetitive transcranial magnetic stimulation (rTMS) and studies of insomnia treatments in older adults and MCI patients using behavioral interventions.  MIRECC investigators currently are also investigating the use of rTMS in cognitive disorders as mediated by BDNF, the effects of exercise on cognition in MCI as mediated by BDNF, and the relationship of obstructive sleep apnea to cognitive losses in older adults. Prior MIRECC work included development of metrics for identifying depression in older adults.

Nusha Askari, PhD
ADRC Senior Administrator

Dr. Askari has extensive clinical research, teaching and administrative experience in neuropsychology and neuropsychiatry, with special focus on dementia. During the past two years, she has been actively engaged in research, education, and outreach efforts with caregivers of persons with chronic depression and dementia. These include caregiving psychoeducational facilitation programs and an equine guided support program, and she volunteers as a medical qigong instructor in an adult day program for persons with dementia and Parkinson’s disease. She is well versed in traditional mindfulness, meditation and healing practices and brings an East meets West integrative perspective to helping and healing. Dr. Askari is former professor and chair, department of Clinical Psychology & Gerontology (Notre Dame de Namur University). She has served on numerous research projects and chaired thesis and dissertation committees.  She speaks English, Farsi, Spanish and French. 

Elizabeth E. Hoyte, BS
ADRC Web Administrator

Elizabeth Hoyte, web administrator for the Stanford Alzheimer’s Disease Research Center, has worked at Stanford University for over 20 years. She also manages websites at Stanford for the Department of Neurology and Neurological Sciences, the Department of Neurosurgery, and over 25 neuroscience research labs. When not developing and managing websites, she is raising two young boys in the beautiful state of Colorado.

Emiko Miyamoto, MS
ADRC Financial Analyst

Emiko Miyamoto is a financial analyst and oversees financial activities of the Stanford ADRC. Prior to joining Stanford’s Neurosurgery and Neurology clinical trials group, she was a senior financial analyst for semiconductor capital equipment companies in the Bay Area.

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