Williams PanLab: Precision Psychiatry and Translational Neuroscience
Our vision for precision psychiatry and neuroscience is to translate insights about the human brain into real world clinical care – to improve the quality of individual lives.
- Mental health disorders are the leading cause of disability worldwide (depressive disorders account for about 40% of the disability, and anxiety disorders are about 15%).
- Advances in human neuroscience give us a better understanding for why one treatment works and another does not - but we have not yet bridged the translational divide between the evidence and how to apply this information in the real world.
To improve this situation, we need to provide more successful treatment.
What we do
Our current projects focus on depression and anxiety, with research that embraces individual differences in the experience of mental health disorders, and the associated disruptions to social and emotional function.
Emotion and cognition are two hallmark features of mental health disorders. Using an integrative approach with MRI, EEG, behavioral testing, genetics, symptoms, and daily functioning data, our research projects aim to:
- delineate neural circuitry for emotional and cognitive functions,
- examine how this circuitry becomes dysregulated in depression and anxiety,
- and assess how it is expressed in individual variations in subjective and behavioral symptoms.