Saijuan Chen, MD

Member of Chinese Academy of Engineering and the Academy of Sciences for the Developing World (TWAS), Foreign Associate of National Academy of Medicine of France, Fellow of the Royal College of Physicians of UK, Vice Chairman of Chinese Association of Science and Technology, Director of National Center for Translational Medicine·Shanghai, Director of State Key Laboratory of Medical Genomics, Director of Shanghai Institute of Hematology

Prof. Sai-Juan Chen is a member of Chinese Academy of Engineering and the Academy of Sciences for the Developing World (TWAS), Foreign Associate of National Academy of Medicine of France, Fellow of the Royal College of Physicians of UK. She holds the positions of Vice Chairman of Chinese Association of Science and Technology, Director of National Center for Translational Medicine·Shanghai, Director of State Key Laboratory of Medical Genomics, and Director of Shanghai Institute of Hematology.

Prof. Chen is engaged in the study of pathogenesis and treatment of leukemia. She initiated Leukemia Genomic Anatomy Project and has obtained a series of novel molecular biomarkers and targets for disease classification, prognosis and targeted therapy. Through screening and validation in large series of acute myeloid leukemia (AML) patients in Chinese population, she also established new diagnostic and prognostic stratification system of AML. These findings have further enriched and shed new light on pathogenesis of leukemia. Based on her understanding of the pathogenesis of leukemia, she innovated the synergistic targeted therapy of leukemia which has turned acute promyelocytic leukemia (APL) from a fatal malignancy to a curable disease, and has been extended to other types of leukemia.

Prof. Chen has published over 300 publications in high level peer reviewed international journals including Nature Genetics, Science, Development Cell, JCI, Nature Commun., Blood and PNAS, with over 20000 citations. Her outstanding work has been recognized by several national awards in science, including Second Prize of National Natural Science Award by State Council of China.