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"Insight into the Sphingolipid and Cholesterol Distribution in the Plasma Membrane Acquired with High-Resolution Secondary Ion Mass Spectrometry" Mammalian cell function is greatly influenced by the abundance of two plasma membrane species: sphingolipids and cholesterol. Yet, the distributions of sphingolipids and cholesterol within the plasma membrane and the mechanisms responsible for this organization are poorly understood. This talk will focus on the use of high-resolution secondary ion mass spectrometry (SIMS) for chemically imaging the distributions of isotope-labeled lipids in the plasma membranes of intact cells with high (<100 nm) lateral resolution.

Department:  Chemistry

Contact: Patricia Dwyer | 650-723-4770 | pdwyer@stanford.edu

Presenter(s):

• Mary Kraft Professor at University of Illionois

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