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Tuberculosis kills more humans than any other single infectious organism and is characterized by a complex interaction between Mycobacterium tuberculosis and its human host. Recent research has demonstrated that human infection exists within a continuous spectrum of bacterial activity and immunological/inflammatory responses than span latent infection, incipient and subclinical disease to active tuberculosis. This seminar will discuss recent insights, through the lens of clinical immunological research in a setting endemic for tuberculosis, into the processes that underlie progression from infection to disease and the implications thereof for tuberculosis prevention strategies such as preventive therapy and vaccination.

Department:  Institute for Immunity, Transplantation and Infection

Contact: Michele King | 650 723 3084 | mking@stanford.edu

Presenter(s):

• Tom Scriba, PhD Professor, University of Cape Town

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