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How AMPA receptor dynamics contribute to tune synaptic plasticity and learning - Daniel Choquet

May 02, 2019 (Thu) | 12:00 PM -1:00 PM
318 Campus Drive, Clark Auditorium : Stanford, CA

The spatio-temporal organization of neurotransmitter receptors in the postsynaptic membrane is a fundamental determinant of synaptic transmission and thus information processing by the brain. Ionotropic AMPA glutamate receptors (AMPAR) mediate fast excitatory synaptic transmission in the central nervous system. Using a combination of high resolution single molecule superresolution imaging and tracking techniques, we have established that AMPARs are not all stable in the synapse as thought initially, but in large part undergo continuous entry and exit to and from the post-synaptic density through lateral diffusion.

Department:  Neurosciences Institute

Contact: Roula J. El-Asmar | 6504501508 | roula@stanford.edu

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