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The generation of neuronal diversity in the nervous system requires the specification and differentiation of a multitude of cellular lineages. The specific genetic programs underlying the differentiation of mature neurons from their progenitors remain incompletely characterized, however, in part because of the difficulty in studying neuronal progenitor cells in their native environments. In the vertebrate olfactory system, primary sensory neurons are continuously regenerated throughout adult life via the proliferation and differentiation of multipotent neural stem cells. Upon severe injury, these adult tissue stem cells are activated and go on to reconstitute all of the cellular constituents of this sensory epithelium.

Department:  Neurosciences Institute

Contact: Roula El-Asmar | 6504978031 | roula@stanford.edu

Presenter(s):

• John Ngai, PhD Professor of Neurobiology at UC Berkeley

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