IBIIS Seminar Series: Large-Scale Inference Across Genomes and Human Diseases with the Global Biobank Engine

Feb 21, 2018 (Wed) | 1:00 PM -2:00 PM
LKSC 120 : Stanford, CA

Abstract: Biobank resources like the UK Biobank contain a wealth of phenotypic information for each subject compared to traditional ascertainment-based studies. However, specific diseases are generally represented near their population prevalence in biobanks which can hamper studies of individual diseases. New statistical methods that can jointly analyze multiple phenotypes are therefore needed to fully take advantage of biobank resources with linked health records and other phenotypic measurements. We have developed a suite of methods to study disease genetics in the context of population-scale biobanks that jointly leverage information from multiple phenotypes to estimate genetic parameters such as genetic correlations, model disease risk, and identify likely...

Department:  Radiology

Contact: Ramzi Totah | 6507214161 |