Stanford Bio-X Frontiers in Interdisciplinary Biosciences Seminar, "Modeling human brain development and disorders using hiPSCs"

Nov 30, 2017 (Thu) | 12:00 PM -1:00 PM
James H. Clark Center, 318 Campus Drive, Seminar Room S360 : Stanford, CA

Lunch to be served at 11:45 AM; seminar begins at 12:00 PM. Three dimensional (3D) cerebral organoid cultures from human iPSCs have been recently developed to recapitulate the cytoarchitecture of the developing brain, which offers unique advantages in understanding molecular and cellular mechanisms governing embryonic neural development and in modeling congenital neurodevelopmental disorders. Dr. Ming's lab has improved the organoid technology and developed a protocol to produce forebrain-specific organoids derived from human iPSCs using a novel miniaturized spinning bioreactor that recapitulate the human embryonic cortical development. She will discuss recent work in using the brain organoids to model and dissect the molecular mechanisms underlying the ZIKV pathogenesis and microcephaly.

Department:  BioX

Contact: Cici Huber | 650-725-7472 |


  • Guo-Li Ming Professor of Neuroscience, Univ. of Pennsylvania SoM

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