Jim Wells, "New Protein Engineered Tools for Signaling"
Oct 20, 2014 (Mon) | 4:00 PM -5:30 PM
318 Campus Drive, Clark Auditorium S001
: Stanford, CA
Cellular phenotypes are the composite of hundreds to thousands of signaling events staged in time and location that resist understanding through simple reductionist approaches. Our lab has been using protein engineering approaches to generate tools that can simplify the analysis of complex pathways in cellular milieu. These tools range from engineered enzymes designed to tag molecular events, selectively ablate cells on command and to new antibody platforms that allow development of the highly selective antibodies to important PTMs such as phosphorylation. These studies employ cellular engineering and novel proteomics approaches to reveal critical nodes and potential new cancer drug targets and biomarkers.
Department: Biology
Contact: Maria Magana-Lopez | 650-723-2413 | mmagana@stanford.edu
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