"Systems Vaccinology: Enabling Rational Vaccine Design with Systems
Biology"
Sep 24, 2014 (Wed) | 2:00 PM -3:30 PM
Alway, M106
: stanford, CA
Despite their great success, we understand little about how effective vaccines stimulate protective immune responses. Two recent developments promise to yield such understanding: the appreciation of the crucial role of the innate immune system in sensing microorganisms and tuning immune responses, and advances in systems biology. In this presentation, I will discuss how these developments are yielding insights into the mechanism of some of the most successful vaccines ever developed. Furthermore, such developments promise to address a major challenge in vaccinology: that the efficacy of a vaccine can only be ascertained retrospectively, upon infection. The identification of molecular signatures induced rapidly after vaccination, which correlate with and predict the later development of pro
Department: Institute for Immunity, Transplantation and Infection
Contact: Michele King | 650 723 3084 | mking@stanford.edu
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