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Chemical & Systems Biology
Cell Signaling
& Physiology
Chemical Biology
Systems Biology
Our Department
The Department of Chemical and Systems Biology explores the molecular mechanisms that underlie cellular function and contribute to human disease. Our laboratories emphasize interdisciplinary research that spans the biomedical sciences, including signal transduction, cell cycle regulation, chromatin remodeling, protein homeostasis, metabolism, and cell differentiation.
By integrating genetic technologies, biochemical and chemical tools, quantitative measurements, and computational modeling, we strive to deconstruct these complex biological systems, predict emergent behaviors, and translate these discoveries into new medical therapies.
The Department of Chemical and Systems Biology explores the molecular mechanisms that underlie cellular function and contribute to human disease. Our laboratories emphasize interdisciplinary research that spans the biomedical sciences, including signal transduction, cell cycle regulation, chromatin remodeling, protein homeostasis, metabolism, and cell differentiation.
By integrating genetic technologies, biochemical and chemical tools, quantitative measurements, and computational modeling, we strive to deconstruct these complex biological systems, predict emergent behaviors, and translate these discoveries into new medical therapies.
Latest
Congratulations to the 2012 Departmental Retreat Award winners!
Winners of the best poster, best paper, and best talk awards at the Annual Chemical and Systems Biology Departmental Retreat are shown here with Joan Mansour, who has generously provided funds for the cash awards as well as a wonderful Read More »
- The Cdk1-APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch.
- A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment.
- A localized Wnt signal orients asymmetric stem cell division in vitro.
- Modification of enhancer chromatin: what, how, and why?
- Selective activation of protein kinase C? in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice.
- Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.
Congratulations to the 2012 Departmental Retreat Award winners!
Winners of the best poster, best paper, and best talk awards at the Annual Chemical and Systems Biology Departmental Retreat are shown here with Joan Mansour, who has generously provided funds for the cash awards as well as a wonderful Read More »
- The Cdk1-APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch.
- A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment.
- A localized Wnt signal orients asymmetric stem cell division in vitro.
- Modification of enhancer chromatin: what, how, and why?
- Selective activation of protein kinase C? in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice.
- Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.
Chemical & Systems Biology
Cell Signaling
& Physiology
Chemical Biology
Systems Biology
Our Department
The Department of Chemical and Systems Biology explores the molecular mechanisms that underlie cellular function and contribute to human disease. Our laboratories emphasize interdisciplinary research that spans the biomedical sciences, including signal transduction, cell cycle regulation, chromatin remodeling, protein homeostasis, metabolism, and cell differentiation.
By integrating genetic technologies, biochemical and chemical tools, quantitative measurements, and computational modeling, we strive to deconstruct these complex biological systems, predict emergent behaviors, and translate these discoveries into new medical therapies.
The Department of Chemical and Systems Biology explores the molecular mechanisms that underlie cellular function and contribute to human disease. Our laboratories emphasize interdisciplinary research that spans the biomedical sciences, including signal transduction, cell cycle regulation, chromatin remodeling, protein homeostasis, metabolism, and cell differentiation.
By integrating genetic technologies, biochemical and chemical tools, quantitative measurements, and computational modeling, we strive to deconstruct these complex biological systems, predict emergent behaviors, and translate these discoveries into new medical therapies.
Latest
Congratulations to the 2012 Departmental Retreat Award winners!
Winners of the best poster, best paper, and best talk awards at the Annual Chemical and Systems Biology Departmental Retreat are shown here with Joan Mansour, who has generously provided funds for the cash awards as well as a wonderful Read More »
- The Cdk1-APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch.
- A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment.
- A localized Wnt signal orients asymmetric stem cell division in vitro.
- Modification of enhancer chromatin: what, how, and why?
- Selective activation of protein kinase C? in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice.
- Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.
Congratulations to the 2012 Departmental Retreat Award winners!
Winners of the best poster, best paper, and best talk awards at the Annual Chemical and Systems Biology Departmental Retreat are shown here with Joan Mansour, who has generously provided funds for the cash awards as well as a wonderful Read More »
- The Cdk1-APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch.
- A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment.
- A localized Wnt signal orients asymmetric stem cell division in vitro.
- Modification of enhancer chromatin: what, how, and why?
- Selective activation of protein kinase C? in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice.
- Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.
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