Wen-Pin Chen received his Ph.D. from National Taiwan University. After completing my thesis work in Professor Ming-Jai Su’s Lab in the Institute of Pharmacology about the mechanisms of the mechanical and electrophysiological modulation of a1-adrenergic activation in normal and cardiomyopathic hearts in 2002. And then, he joined in Drug Research Center at NTU as a postdoctoral fellow to have charge in cardiovascular pharmacology projects including anti-arrhythmic and cardioprotective agents against ischemia-reperfusion injury, drugs anti-diabetic cardiovascular complications and drugs anti-septic cardiomyopathy since 2002. His major research work included using patch clamp technique to characterize the change of cardiac electrophysiology under pathophysiological conditions and the modulation by drugs, measuring Ca2+ transients of single cardiac cells, and using catheter to measure left ventricular pressure and volume to approach hemodynamic function in normal and disease animal models. Being interested in pharmacological screen for drugs that regulate postnatal cardiac progenitor cells, he enters cardiovascular research center of MGH as a research fellow.
Elda Dzilic graduated in 2013 from the Medical University Vienna. Her medical thesis focused on ischemia/reperfusion after myocardial infarction. After receiving her M.D., she began her residency in cardiac surgery at the German Heart Centre Munich in 2013. After joining the Department of Experimental Surgery in her hospital, she developed an interest in the biology of human induced pluripotent stem cells and started in 2014 her research fellowship in Sean Wu’s lab.
Chun-Yuan Chan received his M.S. degree at National Sun Yat-sen University in Taiwan before studying his Ph.D. degree in the Biomedical Science Graduate program at University of New Mexico. His Ph.D. dissertation work focuses on how glucose metabolism regulates V-ATPase function, which maintains pH homeostasis and organelle acidification across all eukaryotic cells. In 2015, he joined Sean Wu’s lab as postdoctoral fellow studying the cellular mechanisms of cardiovascular diseases and potential therapeutic development.
Wenpo Chuang was graduated from National Yang Ming University school of Medicine in Taipei, Taiwan. He subsequently received residency training for internal medicine and cardiology in National Taiwan University Hospital. Since 2006, he joined Far Eastern Memorial Hospital as staff cardiologist. At the meantime, he received cardiac electrophysiology fellowship training in National Taiwan University from 2006 to 2008. He becomes board certified cardiac electro-physiologist and intervention cardiologist in 2008.
Serge Gregoire attended the University of Sherbrooke in Quebec, Canada, from 1999-2001 for his undergraduate training. He majored in biology specializing in biotechnology. This allows him to be recruited in the laboratory of Dr. Xiang-Jiao Yang in the department of Experimental Medicine at McGill University to pursue his PhD. training. He studied the molecular regulatory mechanisms of Myocyte Enhancer Factor 2 (MEF2) family of transcription factors. He has shown that histone deacetylase 4 modulates the sumoylation and phosphorylation of MEF2 proteins. This has allowed him to identify a phospho-sumoyl switch. He has demonstrated that this motif is present in more than 80 proteins and that it serves as a valuable signature for in silico identification of proteins regulated by adjacent phosphorylation and sumoylation. More importantly, the proteins identified by such screening play critical roles in cancer formation/progression, cell signaling, stemness, metabolism, and cytoskeletal regulation, highlighting the physiological significance of this motif.
Markus Krane graduated from the Ludwig Maximillians University School of Medicine in Munich, Germany in 2004. He performed his medical thesis in cardiopulmonary bypass in a pig model in the Department of Experimental Surgery (Prof. Dr. Robert Bauernschmitt) of the German Heart Center Munich. After graduating from medical school he has started his cardiac surgery fellowship training at the German Heart Center Munich in the Department of Cardiovascular Surgery (Prof. Dr. Rüdiger Lange) in 2005. Being interested in embryonic and induced pluripotent stem cell biology in the context of cardiac differentiation/development he has entered the Wu Lab of the cardiovascular research center at the MGH as a research fellow in 2009.
Rajarajan Kuppusamy completed his graduation in the discipline of Animal Physiology with emphasis on assisted reproductive technology from India. He has worked in various assisted reproductive technologies such asIVF, ICSI, Somatic Cell Nuclear Transfer, Vitrification, transgenic andKnock-out and cell culture. Being interested in embryonic stem cells, iPS cells, Assisted Reproductive Technology, transplantation research and regenerative biology, he joined Wu Lab as research fellow in June 2009.
Yuan-Hung Liu was graduated from National Taiwan University School of Medicine in Taipei, Taiwan. He subsequently received internal medicine residency and cardiology fellowship training at National Taiwan University Hospital. Yuan-Hung Liu became CV staff at Far Eastern Memorial Hospital in Taipei in July, 2002. He took responsibility of intensive care and resident training in cardiovascular intensive care unit from 2002 to 2003. Being interested in cardiac electrophysiology, he received cardiac electrophysiology (EP) fellowship training at National Taiwan University Hospital from 2003 to 2006, and then set up EP Lab at Far Eastern Memorial Hospital.
Anthony Sturzu was born in Cupertino, CA and graduated from Monta Vista High School. After competing his undergraduate degree in chemical engineering at UCLA, he attended medical school at Drexel University before returning to the Bay Area to complete his Internal Medicine residency at UCSF. His cardiology training was completed at Massachusetts General Hospital where he first joined the Wu lab. Anthony's research focus involves the use of cell ablation to study developmental and regenerative biology in the mammalian heart.
Min Zeng graduated from the West China University of Medical Science (Sichuan, China). Subsequently she worked in The First affiliated Hospital of The West China University of Medical Science, and Hainan Provincial People's Hospital majoring in cardiology. She participated in the research of the effect evaluation of nasal continuous positive air pressure (n-CPAP) treatment in patient with acute coronary syndrome (ACS) and sleep apnea syndrome (SAS) which was sponsored by Ministry of Health, P.R. China in 2002.And in 2004, she undertook the research financed by Hainan provincial health bureau: A follow up study of incidence of stroke and risk factors in patients with Nonvalvular Atrial Fibrillation(NVAF). Because she has a burgeoning interested in the formation of early stage myocardial lineage commitment by a molecular genetic approach, she joined the Wu lab as a postdoctoral fellow in 2007.
Arun Sharma is a PhD graduate student in the Stanford Biosciences program and is co-mentored by Sean Wu and Joseph Wu. Born in India and raised in Alabama, Arun graduated from Duke University in 2012 with a degree in Biology, Chemistry, and Genome Sciences. As an undergraduate at Duke, he spent a summer in Boston through the Harvard Stem Cell Institute's Summer Internship Program and developed a passion for stem cell biology and regenerative medicine. At Stanford, Arun's research focuses on the applications of induced pluripotent stem cell (iPSC) biology, and specifically, utilizing iPSC-derived cardiomyocytes to model cardiovascular diseases.
Leighton is currently an MD-PhD student in the Stanford Medical Scientist Training Program. Prior to coming to Stanford, he received a BS in Biology from Georgetown University. He was a HHMI undergraduate research scholar at Georgetown, studying RNA-protein interactions of Hepatitis Delta Virus. After graduating in 2013, he spent a year in the National Institute of Allergy and Infectious Disease at the NIH, researching the immune response of Hepatitis C Virus-infected patients treated with direct-acting antivirals. Leighton was born and raised in Denver, Colorado.
Marc Engels grew up and graduated from high school in Curaçao, a Caribbean island forming part of the Dutch Antilles. He attained his propaedeutic exam in Life Science & Technology at Leiden University and Technical University Delft in the Netherlands, before entering Medical School at Leiden University. He combined his studies with a pre-Master program in Biomedical Sciences. After graduating from Medical School in 2009 he joined the Wu lab to work on cardiac stem cell research under the direct mentorship of Sean Wu. Marc is hoping to start with a PhD-training later this year.
Anusha Kumar graduated from Stanford University in 2014, with a BS in Biology and a minor in Philosophy. Her academic concentration was Molecular, Cellular, and Developmental Biology. While an undergraduate, Anusha investigated the hormonal regulation of behavior in African cichlids. She now looks forward to exploring the field of cardiac regenerative medicine and tackling questions with iPSC disease models. When not in lab, Anusha trains in Bharatanatyam (classical Indian dance) and serves as a manager at Pacific Free Clinic in San Jose.
Adele Xu received her undergraduate degree in chemical engineering from Stanford University in 2014, with a focus on biomedical applications. Prior to Stanford she attended high school at St. Paul's School in Concord, NH. She has been working in the Wu lab since June 2014 and hopes to begin pursuing her MD/PhD degree in the autumn of 2015. Her research interests include drug delivery, photochemistry, genome editing, and tissue engineering. In her free time she explores Bay Area running trails and serves as a manager at Pacific Free Clinic in San Jose.
Karolina Plonowska graduated from Monta Vista High School in Cupertino, CA. She completed her undergraduate studies at Cornell University in 2013 with a BA in French and Biological Sciences, concentrating in molecular and cell biology. She has worked for the Wu lab during the summer of 2012 to facilitate the lab’s transition to Stanford. Her interests include IPS disease models and RNA world
Xiaojing graduated from Princeton in 2008 with a BA in chemistry, working on mathematical modelling theory for dynamic systems. Her current interests include cardiac regenerative therapy and the development of IPS disease models.
James Oh graduated from LaGuardia High School for Music and Art in New York, NY. He completed his undergraduate training at the University of North Carolina at Chapel Hill in 2007. While majoring in physics and philosophy, he completed his thesis in biology in Stephen Crews' laboratory where he studied transcriptional regulation. At UNC, James began a stem cell interest group for ethics debates. Furthermore, he has received undergraduate training in Michael Young's lab at The Rockefeller University where he investigated the role circadian proteins.
Esther Yu graduated from Centennial High School in Roswell, GA. She completed her undergraduate training at the Massachusetts Institute of Technology in 2007. Along with majoring in biology at MIT, she worked in the lab of Thijn Brummelkamp at the Whitehead Institute, where she performed RNAi screens to identify and characterize novel genes in various cancer pathways. Furthermore, she investigated methods to use RNAi to selectively target tumorogenic cells.
Nick Flores is an undergraduate student at Stanford University majoring in biology with a minor in chemistry. Nick, a Gates Millennium Scholar, is of Mexican heritage and is fluent in Spanish as well as English. He hopes to attend medical school in 2016 after graduation in pursuit of becoming a physician. Aside from research, he is interested in helping underprivileged areas and volunteers at East Palo Alto Tennis and Tutoring as well as Stanford Pacific Free Clinic in San Jose.
Jennifer Li graduated from Whitney Young High School in Chicago, Illinois, in 2013. Currently an undergraduate at Stanford University, she plans to pursue a degree in Biomechanical Engineering or the Biological Sciences. After completing her undergraduate studies, she hopes to attend medical school and become a physician. She is very eager and excited to become involved in the research conducted by the Sean Wu Lab. In her spare time, she enjoys spending time with her family and friends, running, and exploring the Bay Area.
Ryoko Hamaguchi is an undergraduate student at Stanford University and is mentored by Sean Wu. Born in Japan and raised in Beaverton, Oregon, she is fluent in both Japanese and English. She is currently pursuing a B.S. degree in the Biological Sciences. She hopes to enter a career in medicine, and dreams of becoming a physician skilled in clinical practice as well as in research. Beyond academics, her passions include visual art and volunteering at the Santa Clara Valley Medical Center emergency department.
Alyssa graduated from the University of Massachusetts Amherst in 2004 with a BS in Animal Science. That summer, she joined the CBR Institute for Biomedical Research at Children's Hospital Boston working under Yuko Fujiwara in Fred Alt and Stuart Orkin's transgenic core. Her interests in reproductive physiology led her to Charles River Laboratories working as a reproductive specialist, primarily rederiving investigators' mouse lines. Currently, she is the transgenic core manager for Wu lab, primarily injecting ES and IPS cells into mouse blastocysts. In June 2010 she is attending the cryopreservation of mouse germplasm course at Jackson Laboratory and hopes with its completion, will be added to the transgenic core's services.
Veda Sunkara is currently a junior at Mountain View High School in Mountain View, CA. After gaining some lab experience in an ameba lab over the past summer, she wants to expand her horizons and learn from every possible opportunity that is presented to her. She is excited by the possibilities that the lab's research holds, and cannot wait to be a part of such an incredible venture. She plans to major in journalism and biology when she goes to college, and hopes to one day build establish a series of clinics of her own in Syria to assist war victims. In addition to research, Veda loves to spend time with her family, run, and play the classical guitar.