SCIT Program Seminars
The SCIT program hosts a quarterly colloquium during which two trainees present the status of their research.
Thursday, April 26th
2:30 - 3:30 PM
"Internal Breast Tumor Heterogeneity On T2-Weighted Imaging"
Linxi Shi, PhD
ABSTRACT: Clinically, T2-weighted acquisitions are utilized primarily for the identification of cysts or for adjunct lesion characterization information. However, recent studies have demonstrated the correlation of T2-weighted tumor heterogeneity to response to neoadjuvant chemotherapy, survival outcomes, and histologic grade. In this work, I will briefly talk about the lesion heterogeneity in conventional 3D Spin-Echo T2 (CUBE) versus DESS (Double echo steady state) T2 weighted sequences. These quantitative analysis requires high image quality which is hindered by the non-uniformity artifacts due to B0 and B1 variations. An algorithm for image non-uniformity correction will be introduced for quantitative analysis in breast MRI images.
"An Exploration in Transcranial MRI-guided Focused Ultrasound"
Pooja Gaur, PhD
ABSTRACT: MRI-guided focused ultrasound is increasingly being used to treat brain cancer non-invasively. However, the skull distorts the ultrasound beam and absorbs varying amounts of energy depending on bone thickness and composition, causing delivered acoustic pressure levels to vary by 4x in patients. In light of these challenges, we investigate magnetic resonance acoustic radiation force imaging (MR-ARFI) focal spot imaging of sub-cortical brain tissue in a large animal, and simulations and measurements of acoustic pressure transmitted through the skull. Results show in vivo MR-ARFI focal spot imaging through the skull for the first time, and provide practical information on factors influencing focal spot targeting through the skull.
June 28, 2017
"Efficient Simulation of High Channel Count RF Arrays in Realistic Body Models"
Joshua de Bever, PhD
March 16, 2016
"Magnetotactic Bacteria a Living MRI Tracking Agent"
Ryan Spitler, PhD
March 16, 2016