Member publications employing SCi3 resources
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Jung, K. O. et al. Whole-body tracking of single cells via positron emission tomography. Nature Biomedical Engineering 1–10 (2020) doi:10.1038/s41551-020-0570-5.
Shaffer, T., Gambhir, S. S., Aalipour, A. & Schurch, C. PET imaging of the natural killer cell activation receptor NKp30. J Nucl Med jnumed.119.233163 (2020) doi:10.2967/jnumed.119.233163.
Ilovitsh, T. et al. Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites. PNAS 117, 12674–12685 (2020).
Ren, Y. et al. An NIR-II/MR dual modal nanoprobe for liver cancer imaging. Nanoscale 12, 11510–11517 (2020).
Yao, Y., Cheng, K. & Cheng, Z. Evaluation of a smart activatable MRI nanoprobe to target matrix metalloproteinases in the early-stages of abdominal aortic aneurysms. Nanomedicine: Nanotechnology, Biology and Medicine 26, 102177 (2020).
Kasten, B. B. et al. Targeting MMP-14 for dual PET and fluorescence imaging of glioma in preclinical models. Eur J Nucl Med Mol Imaging 47, 1412–1426 (2020).
Wardak Mirwais et al. Molecular Imaging of Infective Endocarditis With 6′′-[18F]Fluoromaltotriose Positron Emission Tomography–Computed Tomography. Circulation 141, 1729–1731 (2020).
Bose, R. J. C. et al. Reconstructed Apoptotic Bodies as Targeted “Nano Decoys” to Treat Intracellular Bacterial Infections within Macrophages and Cancer Cells. ACS Nano 14, 5818–5835 (2020).
Zhang, Y. et al. Effects of Non-invasive, Targeted, Neuronal Lesions on Seizures in a Mouse Model of Temporal Lobe Epilepsy. Ultrasound in Medicine and Biology 46, 1224–1234 (2020).
Majzner, R. G. et al. Tuning the Antigen Density Requirement for CAR T-cell Activity. Cancer Discov 10, 702–723 (2020).
Theruvath, J. et al. Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors. Nature Medicine 26, 712–719 (2020).
Seo, J. W. et al. Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation. Nature Communications 11, 2102 (2020).
Bachawal, S., Bean, G. R., Krings, G. & Wilson, K. E. Evaluation of ductal carcinoma in situ grade via triple-modal molecular imaging of B7-H3 expression. npj Breast Cancer 6, 1–9 (2020).
Liu, Y. et al. Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI. Scientific Reports 10, 5983 (2020).
Zhang, X. et al. A thiopyrylium salt for PET/NIR-II tumor imaging and image-guided surgery. Molecular Oncology 14, 1089–1100 (2020).
Sukumar, U. K., Rajendran, J. C. B., Gambhir, S. S., Massoud, T. F. & Paulmurugan, R. SP94-Targeted Triblock Copolymer Nanoparticle Delivers Thymidine Kinase–p53–Nitroreductase Triple Therapeutic Gene and Restores Anticancer Function against Hepatocellular Carcinoma in Vivo. ACS Appl. Mater. Interfaces 12, 11307–11319 (2020).
Xiao, Z., Mayer, A. T., Nobashi, T. W. & Gambhir, S. S. ICOS Is an Indicator of T-cell–Mediated Response to Cancer Immunotherapy. Cancer Res (2020) doi:10.1158/0008-5472.CAN-19-3265.
Zlitni, A., Gowrishankar, G., Steinberg, I., Haywood, T. & Sam Gambhir, S. Maltotriose-based probes for fluorescence and photoacoustic imaging of bacterial infections. Nature Communications 11, 1250 (2020).
Ma, L., Huang, S., He, S., Wang, Z. & Cheng, Z. Polydopamine-coated downconversion nanoparticle as an efficient dual-modal near-infrared-II fluorescence and photoacoustic contrast agent for non-invasive visualization of gastrointestinal tract in vivo. Biosensors and Bioelectronics 151, 112000 (2020).
Song, G. et al. Carbon-coated FeCo nanoparticles as sensitive magnetic-particle-imaging tracers with photothermal and magnetothermal properties. Nature Biomedical Engineering 4, 325–334 (2020).
Mbanefo, E. C. et al. Interleukin-4 Signaling Plays a Major Role in Urogenital Schistosomiasis-Associated Bladder Pathogenesis. Infection and Immunity 88, (2020).
Zheng, F. et al. Assessment of Metastatic and Reactive Sentinel Lymph Nodes with B7-H3-Targeted Ultrasound Molecular Imaging: A Longitudinal Study in Mouse Models. Mol Imaging Biol (2020) doi:10.1007/s11307-020-01478-9.
Beinat, C., Patel, C. B., Xie, Y. & Gambhir, S. S. Evaluation of Glycolytic Response to Multiple Classes of Anti-glioblastoma Drugs by Noninvasive Measurement of Pyruvate Kinase M2 Using [18F]DASA-23. Mol Imaging Biol 22, 124–133 (2020).
Hsu, E.-C. et al. Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1. PNAS 117, 2032–2042 (2020).
Li, Y., Li, D., Wu, H., Huang, J. & Cheng, Z. Synthesis and Application of a Long-Circulating Radiolabeled Peptide for Targeting of Osteosarcoma. Mol Imaging Biol (2020) doi:10.1007/s11307-019-01468-6.