Download* a mo vie of various narcoleptic episodes in both human and animals. Note that both sporadic, dogs and human patients are hypocretin/orexin deficient. The early onset case was found to have a mutation in the preprohypocretin gene. Familial canine narcolepsy are due to mutations in the hypocretin receptor2 genes.

Download* a movie of a 3 year old narcoleptic weimaraner with hypocretin deficiency.

Download* a movie of a narcoleptic mice. The mice model is a preprohypocretin knockout mice (courtesy of Dr. Yanagisawa, Texas, USA, 14Mb)

Download* a movie of a narcoleptic Doberman (Hypocretin receptor-2 mutation) and a narcoleptic Dachshund (sporadic hypocretin deficient dog) (34 Mb)


Download* a movie of a 9 year old child. Note that narcolepsy-cataplexy started when this child was 6 month old. This case is the only known child with a mutation in the preprohypocretin gene (courtesy of Dr. Nevsimalova, Prague, Czech republic, 19 Mb)

* Please note that some files are BinHexed (.hqx) and all files are in the Quicktime (.MOV) movie format. Most browsers (PC and MAC) will be able to decode the BinHex format.