Publications

Recent Publications (10 of 293)

  1. Barzaghi F, Amaya Hernandez LC, Neven B, et al. Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study. J Allergy Clin Immunol. 2018. doi:10.1016/j.jaci.2017.10.041.
  2. Pellerin L, Jenks JA, Chinthrajah S, et al. Peanut-specific type 1 regulatory T cells induced in vitro from allergic subjects are functionally impaired. J Allergy Clin Immunol. 2018;141(1):202-213.e8. doi:10.1016/j.jaci.2017.05.045.
  3. Kunicki MA, Amaya Hernandez LC, Davis KL, Bacchetta R, Roncarolo MG. Identity and Diversity of Human Peripheral Th and T Regulatory Cells Defined by Single-Cell Mass Cytometry. J Immunol. 2018;200(1):336-346. doi:10.4049/jimmunol.1701025.
  4. Cicalese MP, Ferrua F, Castagnaro L, et al. Gene Therapy for Adenosine Deaminase Deficiency: A Comprehensive Evaluation of Short- and Medium-Term Safety. Mol Ther. 2018;26(3):917-931. doi:10.1016/j.ymthe.2017.12.022.
  5. Migliavacca M, Assanelli A, Ponzoni M, et al. First Occurrence of Plasmablastic Lymphoma in Adenosine Deaminase-Deficient Severe Combined Immunodeficiency Disease Patient and Review of the Literature. Front Immunol. 2018;9:113. doi:10.3389/fimmu.2018.00113.
  6. Gregori S, Roncarolo MG. Engineered T Regulatory Type 1 Cells for Clinical Application. Front Immunol. 2018;9:233. doi:10.3389/fimmu.2018.00233.
  7. Locafaro G, Andolfi G, Russo F, et al. IL-10-Engineered Human CD4(+) Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism. Mol Ther. 2017;25(10):2254-2269. doi:10.1016/j.ymthe.2017.06.029.
  8. Sayos J, Wu C, Morra M, et al. Pillars Article: The X-Linked Lymphoproliferative Disease Gene Product SAP Regulates Signals Induced through the Co-Receptor SLAM. Nature. 1998. 395: 462-469. J Immunol. 2017;199(5):1534-1541.
  9. Santoni de Sio FR, Passerini L, Valente MM, et al. Ectopic FOXP3 Expression Preserves Primitive Features Of Human Hematopoietic Stem Cells While Impairing Functional T Cell Differentiation. Sci Rep. 2017;7(1):15820. doi:10.1038/s41598-017-15689-8.
  10. Fuchs A, Gliwinski M, Grageda N, et al. Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Front Immunol. 2017;8:1844. doi:10.3389/fimmu.2017.01844.

Featured Publications (12 of 293)

  1. Akbarpour M, Goudy KS, Cantore A, Russo F, Sanvito F, Naldini L, Annoni A, Roncarolo MG (2015). Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs. Sci Transl Med. 27;7(289):289ra81.
  2. R. Bacchetta, B. Lucarelli, C. Sartirana, S. Gregori, M.T. Lupo Stanghellini, P. Miqueu, S. Tomiuk, M. Hernandez-Fuentes, M.E. Gianolini, R. Greco, M. Bernardi, E. Zappone, S. Rossini, U. Janssen, A. Ambrosi, M. Salomoni, J. Peccatori, F. Ciceri, and M.G. Roncarolo (2014). Immunological outcome in haploidentical-HSC transplanted patients treated with IL-10-anergized donor T cells. Front Immunol 5: 16.1-13.
  3. N. Gagliani, C.F. Magnani, S. Huber, M.E. Gianolini, M. Pala, P. Licona-Limon, B. Guo, D.R.Herbert, Bulfone, F. Trentini, C. Di Serio, R. Bacchetta, M. Andreani, L.Brockmann, S. Gregori, R. Flavell, and M.G. Roncarolo(2013). Co-expression of CD49b and LAG-3 identifies human and murine Tr1 cells. Nat Med 19: 739-746.
  4. A. Biffi, E. Montini, L. Lorioli, M. Cesani, F. Fumagalli, T. Plati, C. Baldoli, S. Martino, A. Calabria, S. Canale, F. Benedicenti, G. Vallanti, L. Biasco, S. Leo, N. Kabbara, G. Zanetti, W.B. Rizzo, N.A. Mehta, M.P. Cicalese, M. Casiraghi, J.J. Boelens, U. Del Carro, D.J. Dow, M. Schmidt, A. Assanelli, V. Neduva, C. Di Serio, E. Stupka, J. Gardner, C. von Kalle, C. Bordignon, F. Ciceri, A. Rovelli, M.G. Roncarolo, A. Aiuti, M. Sessa, and L. Naldini (2013). Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy. Science 341: 1233158.
  5. A. Aiuti, L. Biasco, S. Scaramuzza, F. Ferrua, M.P. Cicalese, C. Baricordi, F. Dionisio, A. Calabria, S. Giannelli, M.C. Castiello, M. Bosticardo, C. Evangelio, A. Assanelli, M. Casiraghi, S. Di Nunzio, L. Callegaro, C. Benati, P. Rizzardi, D. Pellin, C. Di Serio, M. Schmidt, C. von Kalle, J. Gardner, N. Mehta, V. Neduva, D.J. Dow, A. Galy, R. Miniero, A. Finocchi, A. Metin, P. Banerjee, J.S. Orange, S. Galimberti, M.G. Valsecchi, A. Biffi, E. Montini, A. Villa, F. Ciceri, M.G. Roncarolo*, and L. Naldini * (2013).  Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich Syndrome. Science 341: 1233151. *Equal contribution. 
  6. A. Aiuti, F. Cattaneo, S. Galimberti, U. Benninghoff, B. Cassani, L. Callegaro, S. Scaramuzza, G. Andolfi, M. Mirolo, I. Brigida, A. Tabucchi, F. Carlucci, M. Eibl, M.Aker, S. Slavin, H. Al-Mousa, A. Al Ghonaium, A. Ferster, A. Duppenthaler, L. Notarangelo, R. Buckley, M. Bregni, S. Marktel, M.G.Valsecchi, P. Rossi, F. Ciceri, R. Miniero, C. Bordignon, and M.G. Roncarolo (2009). Gene Therapy for immunodeficiency due to adenosine deaminase deficiency. N Engl J Med 360: 447-458.
  7. M. Battaglia, A. Stabilini, B. Migliavacca, J. Horejs-Hoeck, T. Kaupper, and M.G. Roncarolo (2006). Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and Type 1 diabetic patients. J Immunol 177: 8338-8347.
  8. R. Bacchetta, L. Passerini, E.Gambineri, M. Dai, S.E.Allan, L. Perroni, F. Dagna-Bricarelli, C. Sartirana, S. Matthes-Martin, A. Lawitschka, C. Azzari, S.F. Ziegler, M.K. Levings, and M.G. Roncarolo (2006). Defective regulatory and effector T cell functions in patients with FOXP3 mutations. J Clin. Invest 116:1713-1722.
  9. M. Battaglia, A. Stabilini ,  E. Draghici , B. Migliavacca,  S. Gregori , E. Bonifacio,  and M.G. Roncarolo  (2006). Induction of tolerance in type I diabetes via both CD4+CD25+ T regulatory cells and T regulatory type I cells. Diabetes 55: 1571-1580.
  10. L. Dupré, A. Aiuti, S. Trifari, S. Martino, P. Saracco, C. Bordignon and M.G. Roncarolo (2002). Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation. Immunity 17: 157-166.
  11. H. Groux, A. O'Garra, M. Bigler, M. Rouleau, S. Antonenko, J.E. de Vries and M. G. Roncarolo (1997).  A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389:737-742.
  12. A.W. Flake, M.G. Roncarolo, J. Puck, G. Almeida-Porada, M. Evans, M. Johnson, E. Abella, D. Harrison, and E. Zanjani (1996). Treatment of X-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow. New Engl J Med 335:1806-1810.

 

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