Research Management Group (RMG)

The V Foundation for Cancer Research
BRCA 1, 2 Research Collaborative Research Grants

Limited $600,000 funding opportunity for Stanford faculty with UTL, MCL, and NTLR appointments. Please see Stanford eligibility clarification below. They are interested in any cancer type that is associated with inherited BRCA mutations. Please see Stanford eligibility and amount of funding and “translational" and "convergence" grant type descriptions below.

 

The internal selection process for 2017 has been completed. This webpage is for your reference only.



# applicants: 2**
**Each institution may nominate one Lead PI in each grant category to submit an application. Categories:


Timeline

Stanford Cancer Institute internal deadline:  May 8, 2017, 5 p.m. (see internal submission guidelines below)
Cancer Institute will notify the applicant selected: June 9, 2017
Cancer Institute to submit the Nomination form and Letter of Intent to the foundation by June 12, 2017, 5 p.m. ET
If invited to submit a full proposal* (you will receive online login credentials to complete the full proposal):
Full proposal (by invitation only) deadline: September 2017
*If invited to submit a full proposal, please notify your RPM in RMG asap

Guidelines
The V Foundation submits Requests for Proposals (RFPs) to the directors of the National Cancer Institute (NCI)-designated facilities and prominent universities involved in critical cancer research throughout the United States.
Download a PDF file of the guidelines


Amount of funding & grant type descriptions:


Eligibility:


Purpose:


The V Foundation is pleased to announce a new grant opportunity. The BRCA Foundation and the Basser lnitiative at the Gray Foundation have challenged The V Foundation to seek contributions to fund BRCArelated cancer research. If the entire challenge is met, $6 million will be invested in this research. In preparation for this funding, a special call for applications for the 2017 BRCA Research Collaborative Grants is now issued. We are seeking grant applications for high risk, high reward multi-disciplinary convergence research and innovative translational research.

BRCA1 and BRCA2 are human genes that produce tumor suppressor proteins. These proteins help repair damaged DNA and, therefore, play a role in ensuring the stability of the cell’s genetic material. When either of these genes is mutated, or altered, such that its protein product either is not made or does not function correctly, DNA damage may not be repaired properly. As a result, cells are more likely to develop additional genetic alterations that can lead to cancer.

Specific inherited mutations in BRCA1 and BRCA2 increase the risk of female breast and ovarian cancers, and they have been associated with increased risks of several additional types of cancer. Together, BRCA1 and BRCA2 mutations account for about 20 to 25 percent of hereditary breast cancers and about 5 to 10 percent of all breast cancers. In addition, mutations in BRCA1 and BRCA2 account for around 15 percent of ovarian cancers overall. Breast and ovarian cancers associated with BRCA1 and BRCA2 mutations tend to develop at younger ages than their nonhereditary counterparts.


INTERNAL SUBMISSION GUIDELINES

By May 8, 2017, 5 p.m. please submit one PDF file [File name: Last name_V_Foundation_BRCA.pdf] of the following via email attachment to:

Denise Baughman
Project Manager
Stanford Cancer Institute
deniseb@stanford.edu

Institutional representative: not applicable. You do not have to submit your internal proposal through your RPM in RMG for their approval. You can submit it directly to Denise per these instructions.

Title Page (count as page zero)
The V Foundation for Cancer Research
2017 BRCA 1, 2 Research Collaborative Grant Program
Project Title:
Indicate grant type (select one): Translational or Convergence Award
Lead PI: First and Last Name, Degrees, Academic Title, Department, mailing address, Email address and phone number
Collaborating investigator(s):
First and names, academic title, department, institution, email address

Proposal (3 page limit):
Page 1-2: Describe what your research is and the impact it will have.
Page 3: Describe the People, Expertise and Research Environment for the project

 

Contact/Questions:
Denise Baughman
Project Manager
Administration Office
Stanford Cancer Institute
Lorry Lokey Stem Cell Building/SIM 1
265 Campus Drive
Stanford, CA 94305-5456
t 650-724-9547
f 650-736-0607
deniseb@stanford.edu

 


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