Research Management Group (RMG)

NIH Office of Research Infrastructure Programs (ORIP)
Shared Instrumentation for Animal Research (SIFAR) Grant (S10) PAR-17-075

**University-wide internal vetting process required for the proposal for the following new NIH Shared Instrumentation for Animal Research (SIFAR) Grant Program.

This FOA will support NIH-funded investigators engaged in biomedical research using animals, to seek support for high-cost, state-of-the-art, commercially available scientific instruments. All requested instruments must be used on a shared basis and enhance research that uses animals or related materials such as animal tissues, cells or germplasm.

If a cluster/series of instruments is requested, it must include an item that costs at least $50,000. The least expensive instrument in a cluster/series must cost at least $20,000. If a single instrument is requested, it must cost at least $50,000. There is no upper limit on the cost of each instrument, but the maximum award is $750,000.
Note: a single instrument may be requested through the SIFAR only if it is to be placed in a barrier facility. See the eligibility and purpose sections below.

**NOTE: the NIH requires that the PD/PI chosen for this application should have documented (in the biographical sketch) technical expertise directly related to the requested instrumentation or scientific expertise in biomedical research using animals. The PD/PI does not need to have an NIH research grant or any other research support, and may be a Core director**, tenured or non-tenured faculty member of the applicant organization.

The vetting process for other S10 programs:
Please use the SIFAR-animal research S10 for any single instrument requests to be placed in barrier facilities.
Please use the SIG or HEI applications for any single instrument requests to be placed outside barrier facilities.

Internal vetting process deadline*: Tuesday, March 21, 2017 (see the internal vetting process submission guidelines below)
Applicants will be notified about the status of their proposals as soon as possible.
Letter of intent: not applicable
Institutional representative deadline: May 24, 2017 (per the internal proposal deadline policy)
Application deadline: May 31, 2017

*Note: Rare Exception-PI waiver request packet* deadline for Core Directors: March 14, 2017, 5 p.m.
(see below for waiver request instructions >>)

Program announcement:
Please read the eligibility criteria and the internal vetting process submission guidelines on this webpage.
Program announcement:

# of applicants: Even though the program announcement indicates unlimited applications are permitted (no duplicate instruments), the university is requiring a vetting process. Only internal "vetted" proposals approved by internal review committee(s) will be able to submit a subsequent full application.
Why there is a vetting process: There is no restriction on the number of applications an institution can submit to the SIFAR, SIG and/or High-End Instrumentation (HEI) Programs each year provided the applications request different types of equipment. In general, concurrent SIFAR, SIG (PAR-17-074) and/or HEI (PAR-17-076) applications for the same instruments (or the same type of instrument with added special accessories to meet the HEI budget requirement or the same instrument which is a part of a SIFAR cluster) are not allowed. If two or more S10 (either SIFAR, SIG or HEI) applications are submitted for similar equipment from the same institution, documentation from a high level institutional official must be provided, stating that this is not an unintended duplication, but part of a campus-wide instrumentation plan. [Jeanne Heschele will assist PIs with obtaining letter of support from Dr. Arvin justifying any similar instrument requests.]   The vetting process will also confirm the PI for the proposed instrumentation has the documented technical expertise related to the proposed instrument.


Amount of funding:



The Shared Instrumentation for Animal Research (SIFAR) Grant Program invites groups of NIH-funded investigators engaged in biomedical research using animals, to seek support for high-cost, state-of-the-art, commercially available scientific instruments. All requested instruments must be used on a shared basis and enhance research that uses animals or related materials such as animal tissues, cells or germplasm.


Mechanism of Support:
Under the S10 mechanism, funding requests are limited to the purchase cost of the instrument only. Support for technical personnel, service contracts, extended warranties, and supplies are not allowable. Cost sharing towards purchase of the instrument is not required. If the amount of funds requested does not cover the total cost of the instrument, the application should describe the proposed source(s) of funding for the balance of the cost of the instrument. Documentation of the availability of the remainder of funding, signed by an appropriate institutional official, should be included in the application and must be presented to NIH prior to issuance of award.

The program does not provide facilities and administrative (F&A) costs or support for construction or alterations or renovations. Matching funds are not required. However, commitment of an appropriate level of institutional support to ensure the associated sustaining infrastructure is expected and should be described. Appropriate Grants will be awarded for a period of one year and are not renewable. Supplemental applications will not be accepted.

The SIFAR program will NOT support requests for:



By Tuesday, March 21, 2017, 5 p.m., please submit one PDF file containing the following in the order listed below to:
Jeanne Heschele
Research Management Group

File name: Last name_NIH_SIFAR_2017.pdf

Format: single-spaced Arial or Helvetica size 11 font or larger, 1/2 magins

1) Proposal (up to 5 pages):
NIH Shared Instrumentation for Animal Research (SIFAR) Grant
PI name, title, department, address, email address
Proposal Title
Type of Instrument (make, model)
Estimated total cost (reminder: the base cost of the instrument should be at least $50,000)
Location of instrument (name of core facility, building location)
Proposal should also include a narrative: introduction, scientific purpose, justification of the need.
Major user groups, names, titles, departments (see eligibility: a major user group of three or more investigators who are Principal Investigators on active NIH research grants with the following activity codes, P01, R01, U01, R35, R37, DPI and DP2 must be identified.
Projects supported by NIH research grants should require at least 75 percent of the AUT (accessible user time). The major user group accounts for at least 35 percent of the AUT (accessible user time)

2) Letter from your department chair addressed to the NIH Shared Instrumentation Internal Vetting Process Committee

3) Biosketch for the PI. This biosketch should document the PI's required technical expertise relating to the instrument chosen.

4) List of similar instruments:
Contact the Property Management Office PMO contact information >> and request that they generate a list of similar instruments for you.
Please ask Property Management include the search terms that were used to generate the list they provide you.

(Note: This list is requested because the "Justification of need" section of the application, requires that PIs "provide an inventory of similar instruments existing at your institution, neighboring research institutions, or otherwise accessible; describe why each similar instrument is unavailable or inappropriate for the proposed research. If similar instruments are listed as 'unavailable'," PIs will need to include in their final applications-not for the internal vetting process- from each instrument manager (core director) explaining why the instrument is not available to your user group.

5) Copy of the approved "Rare Exception PI waiver request packet" - this applies only If the PI is the Core (Service Center/Shared Facility) Director is the PI for the proposal because he/she has the required, documented technical expertise for the proposed instrument and a faculty member does not). Core Directors: please download the Rare Exception PI waiver-Core Director SIFAR instructionspdf file


Selection process
All of the Stanford University SIFAR, SIG and HEI proposals will be reviewed and vetted and will be notified about the status of the proposals as soon as possible after the internal vetting deadline

IMPORTANT NOTE: Shared Facility/Service Center Resources- Dean's office
You are encouraged to discuss shared facility, service center, core facility resources with Bruce Koch, Senior Director, Discovery and Technological Service Centers, Office of the Senior Associate Dean for Research at

Institutional Representative internal deadline:
You are encouraged to notify your RPM as soon as possible that you will be submitting a proposal so he/she can begin to generate your budget and assist with other aspects of your application.
School of Medicine:
Internal proposal submission policy change:
Research Process Manager (RPM) department assignments: more >>
Faculty in other schools:
Download the Pre-award OSR department assignments on this DoResearch webpage >>

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