Research Management Group (RMG)

NIH Shared Instrumentation for Animal Research (SIFAR) Grant (S10) PAR-18-599

**University-wide internal vetting process required for the proposal for the following NIH Shared Instrumentation for Animal Research (SIFAR) Grant Program.

This funding opportunity announcement (FOA) does NOT support requests for single instruments. Applicants may request clusters of commercially available instruments configured as specialized integrated systems or as series of instruments to support a thematic well-defined area of research using animals or related materials. Priority will be given to uniquely configured systems to support innovative and potentially transformative investigations.

At least one item of the requested instrumentation must cost at least $50,000, after all applicable discounts. No instrument in a cluster can cost less than $20,000, after all applicable discounts. There is no maximum price requirement; however, the maximum award is $750,000.

This FOA supports requests for state-of-the art commercially available technologies needed for NIH-funded research using any vertebrate and invertebrate animal species. All requested instruments must be used on a shared basis and enhance research that uses animals or related materials such as animal tissues, cells, or germplasm.

See the eligibility and purpose sections below.

The vetting process for other S10 programs:
These programs permit requests for single instruments:


Program announcement:
Please read the eligibility criteria and the internal vetting process guidelines on this webpage.
Program announcement:

# of applicants: Even though the program announcement indicates unlimited applications are permitted (no duplicate instruments), the university is requiring a vetting process.

Only internal "vetted" proposals approved by internal review committee(s) will be able to submit a subsequent full application.

Why there is a vetting process
: There is no restriction on the number of applications an institution can submit to the SIFAR, SIG and/or High-End Instrumentation (HEI) Programs each year provided the applications request different types of equipment. In general, concurrent SIFAR, SIG (PAR-17-074) and/or HEI (PAR-17-076) applications for the same instruments (or the same type of instrument with added special accessories to meet the HEI budget requirement or the same instrument which is a part of a SIFAR cluster) are not allowed. If two or more S10 (either SIFAR, SIG or HEI) applications are submitted for similar equipment from the same institution, documentation from a high level institutional official must be provided, stating that this is not an unintended duplication, but part of a campus-wide instrumentation plan. [Jeanne Heschele will assist PIs with obtaining letter of support from Dr. Arvin justifying any similar instrument requests.]   The vetting process will also confirm the PI for the proposed instrumentation has the documented technical expertise related to the proposed instrument.


Amount of funding:





Mechanism of Support:
Under the S10 mechanism, funding requests are limited to the purchase cost of the instrument only. Support for technical personnel, service contracts, extended warranties, and supplies are not allowable. Cost sharing towards purchase of the instrument is not required. If the amount of funds requested does not cover the total cost of the instrument, the application should describe the proposed source(s) of funding for the balance of the cost of the instrument. Documentation of the availability of the remainder of funding, signed by an appropriate institutional official, should be included in the application and must be presented to NIH prior to issuance of award.

The program does not provide facilities and administrative (F&A) costs or support for construction or alterations or renovations. Matching funds are not required. However, commitment of an appropriate level of institutional support to ensure the associated sustaining infrastructure is expected and should be described. Appropriate Grants will be awarded for a period of one year and are not renewable. Supplemental applications will not be accepted.

The SIFAR program will NOT support requests for:



By Tuesday, March 20, 2018, please submit one PDF file containing the following in the order listed below to:

Jeanne Heschele
Research Management Group

File name: Last name_NIH_SIFAR_2018.pdf

Format: single-spaced Arial or Helvetica size 11 font or larger, 1/2 magins

1) Proposal (up to 5 pages):
NIH Shared Instrumentation for Animal Research (SIFAR) Grant (PAR-18-599)
PI name, title, department, address, email address
Proposal Title
Type of Instruments (makes, models) in your cluster of commercially available instruments configured as specialized integrated systems or as a series of instruments to support a thematic well-defined area of research using animals or related materials. (Reminder: single instruments are not permitted for this FOA.)
Estimated total cost (reminder: At least one item of the requested instrumentation must cost at least $50,000, after all applicable discounts. No instrument in a cluster can cost less than $20,000, after all applicable discounts. There is no maximum price requirement; however, the maximum award is $750,000
Location of your cluster of instruments--specialized integrated system or your series of instruments (name of core facility, building location)
Proposal should also include a narrative: introduction, scientific purpose, justification of the need.
Major user groups, names, titles, departments (see eligibility: a major user group of three or more investigators who are Principal Investigators on active NIH research grants with the following activity codes, P01, R01, U01, R35, R37, DPI and DP2 must be identified. (see eligibility)
Projects supported by NIH research grants should require at least 75 percent of the AUT (accessible user time). The major user group accounts for at least 35 percent of the AUT (accessible user time)

2) Letter from your department chair addressed to the NIH Shared Instrumentation Internal Vetting Process Committee

3) Biosketch for the PI. This biosketch should document the PI's required technical expertise relating to the instrument chosen.

4) List of similar instruments:
Instructions for obtaining the list: by March 12, 2018, PIs should contact Stan Dunn in the Property Management Office at (see the timeline above) and request that he generates a list of similar instruments for your your NIH Instrumentation internal vetting process proposal. Please provide the specific manufacture/model of the instrument. If examples of similar instruments can also be provided, that is very helpful. Stan will provide you with a memo containing the search terms and results that must be included with your internal vetting process proposal. (You are encouraged to obtain this early on in the process but please request no later than March 12.)

NOTE: This list is requested because the "Justification of need" section of the application, which requires that PIs "provide an inventory of similar instruments existing at your institution, neighboring research institutions, or otherwise accessible; describe why each similar instrument is unavailable or inappropriate for the proposed research.” If similar instruments are listed as 'unavailable', PIs will need to include in their final applications (see the Letters of Support section in the guidelines) from each instrument manager (core director) explaining why the instrument is not available to your user group.

5) Copy of the approved "Rare Exception PI waiver request packet" - this applies only If the PI is the Core (Service Center/Shared Facility) Director is the PI for the proposal because he/she has the required, documented technical expertise for the proposed instrument and a faculty member does not). Core Directors: please download the Rare Exception PI waiver-Core Director SIFAR instructionspdf file


6) Resubmission:
Please see the above section on “resubmission” under eligibility (about checking with your program officer and discussing the new requirement that the PI must have documented evidence in your attached biosketch that you have the technical expertise that is directly related to the type of instrument chosen, and if, you’ll have to have someone who meets the criteria be the PI. If that PI is a Core Director, then that Core Director will need to contact me to obtain instructions for obtaining a “Rare Exception PI waiver” request. If you have the required expertise and want to “resubmit” your SIG proposal- for this internal vetting process you will:


Selection process
All of the Stanford University SIFAR, SIG and HEI proposals will be reviewed and vetted and will be notified about the status of the proposals as soon as possible after the internal vetting deadline

IMPORTANT NOTE: Shared Facility/Service Center Resources- Dean's office
You are encouraged to discuss shared facility, service center, core facility resources with Bruce Koch, Senior Director, Discovery and Technological Service Centers, Office of the Senior Associate Dean for Research at

Institutional Representative internal deadline:
You are encouraged to notify your RPM as soon as possible that you will be submitting a proposal so he/she can begin to generate your budget and assist with other aspects of your application.
School of Medicine:
Internal proposal submission policy change:
Research Process Manager (RPM) department assignments: more >>
Faculty in other schools:
Download the Pre-award OSR department assignments on this DoResearch webpage >>

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