Research Management Group (RMG)

NIH Office of Research Infrastructure Programs (ORIP)
Shared Instrumentation Grant PAR-15-088

**University-wide internal vetting process required for the proposal for the following NIH Shared Instrumentation Program (SIG).**

This program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instruments or integrated systems that cost at least $50,000. The maximum award is $600,000.

[See the separate internal vetting process required for the NIH High-End Instrumentation Grant program ($600K-$2M )-March 23rd deadline-more >> ]

Important- **new this year** the NIH requires that the PI must have documented (as shown in his/her biosketch) evidence of technical expertise directly related to the type of instrument proposed (see eligibility for additional information).

# of applicants: Even though the program announcement indicates unlimited applications are permitted (no duplicate instruments), the university is requiring a vetting process. Only internal "vetted" proposals approved by internal review committee(s) will be able to submit a subsequent full application. See "why the internal vetting process is required".

Rare Exception-PI waiver request packet* deadline for Core Directors: March 9, 2015*
*contact Jeanne Heschele at for the waiver request packet instructions.

Internal vetting process deadline: Monday, March 16, 2015, 5 p.m. (see the internal vetting process submission guidelines below)
Applicants will be notified about the status of their proposals:
Letter of intent: not applicable
Application deadline: May 29, 2015

Program announcement:
Please read see the eligibility criteria below and the internal vetting process guidelines below as well.


Previous awardees (2005-2014)


Amount of funding:
The SIG program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instruments or integrated systems with a base cost of at least $50,000. The maximum award is $600,000.
Awards are for one year and for direct costs only. Cost sharing is not required.
Funds Available and Anticipated Number of Awards: ORIP intends to award an estimate of 80 awards corresponding to a total of $40 million in FY2016. See mechanism of support section for more information.




*Per the guidelines-why the vetting process is necessary
There is no restriction on the number of applications an institution can submit to the SIG and/or High-End Instrumentation (HEI) Programs each year provided the applications request different types of equipment. Concurrent SIG and/or HEI applications for the same instrument (or the same type of instrument with added special accessories to meet the HEI budget requirement) are not allowed, in general. If two or more S10 (either SIG or HEI) applications are submitted for similar equipment from the same institution, documentation from a high level institutional official must be provided stating that this is not an unintended duplication, but part of a campus wide instrumentation plan.
New this year, the vetting process will confirm the PI for the proposed instrumentation has the documented technical expertise related to the proposed instrument.

The purpose of this funding opportunity is to continue the Shared Instrumentation Grant (SIG) Program administered by ORIP. The objective of the Program is to make available to institutions expensive research instruments that can only be justified on a shared-use basis and that are needed for NIH-supported projects in basic, translational or clinical areas of biomedical/behavioral research. The SIG Program provides funds to purchase or upgrade a single item of expensive, specialized, commercially available instrument or an integrated instrumentation system. An integrated instrumentation system is one in which the components, when used in conjunction with one another, perform a function that no single component could provide. The components must be dedicated to the system and not used independently.

Types of supported instruments include, but are not limited to: x-ray diffractometers, electron and confocal microscopes, mass and nuclear magnetic resonance (NMR) spectrometers, protein and DNA sequencers, biosensors, cell sorters, and biomedical imagers. Applications for "stand alone" computer systems (supercomputers, computer clusters and storage systems) will only be considered if the instrument is solely dedicated to the research needs of a broad community of NIH-supported investigators.

Instruments must be for research purposes only. Applications for research on advancing the design or for the development of new instrumentation are not appropriate for this Funding Opportunity Announcement (FOA).

Foreign-made equipment is allowable.

Applicants are advised to discuss with the SIG Scientific/Research Contact (see the guidelines) any questions about appropriate types of equipment, eligibility, and Program requirements, prior to submitting an application for an integrated instrumentation system.


Mechanism of Support:
Under the S10 mechanism, funding requests are limited to the purchase cost of the instrument only. Support for technical personnel, service contracts, extended warranties, and supplies are not allowable. Cost sharing towards purchase of the instrument is not required. If the amount of funds requested does not cover the total cost of the instrument, the application should describe the proposed source(s) of funding for the balance of the cost of the instrument. Documentation of the availability of the remainder of funding, signed by an appropriate institutional official, should be included in the application and must be presented to NIH prior to issuance of award.
The program does not provide facilities and administrative (F&A) costs or support for construction or alterations or renovations. Matching funds are not required. However, commitment of an appropriate level of institutional support to ensure the associated sustaining infrastructure is expected and should be described. Appropriate Grants will be awarded for a period of one year and are not renewable. Supplemental applications will not be accepted.


Principal Investigator/Advisory Committee (highlights from program announcement)
Each applicant institution must propose a Principal Investigator who can assume administrative/scientific oversight responsibility for the instrumentation requested. This person need not be an NIH grantee but must be affiliated with the applicant institution and registered on the eRA Commons. An internal advisory committee must be named to assist the Principal Investigator in administering the grant and overseeing the usage of the instrument.
The Principal Investigator and the advisory committee are responsible for the development of guidelines for:


The SIG program will not support requests for:


Internal Vetting Process Submission Guidelines

By Monday, March 16, 2015, 5 p.m., please submit one PDF file containing the following in the order listed below to:
Jeanne Heschele
Research Management Group

File name: Last name_NIH_SIG_2015.pdf

Format: single-spaced size 11 font, 1/2 magins

1) Proposal (up to 4 pages):
Name of the RFA: NIH ORIP Shared Instrumentation Program (SIG) PAR15-088
PI name, title, department, address, email address
Proposal Title
Type of Instrument (make, model)
Estimated total cost (reminder: the base cost of the instrument should be at least $50,000)
Location of instrument (name of core facility, building location)
Major user groups, names, titles, departments (see eligibility: a major user group of three or more investigators who are Principal Investigators on active NIH research grants with the following activity codes, P01, R01, U01, R35, R37, DPI and DP2 must be identified.
Projects supported by NIH research grants should require at least 75 percent of the AUT (accessible user time). The major user group accounts for at least 35 percent of the AUT (accessible user time)

2) Letter from your department chair addressed to the NIH Shared Instrumentation Internal Vetting Process Committee

3) Biosketch for the PI. This biosketch should document the PI's required technical expertise relating to the instrument chosen.

4) Copy of the approved "Rare Exception PI waiver request packet" - this applies only If the PI is the Core (Service Center/Shared Facility) Director is the PI for the proposal because he/she has the required, documented technical expertise for the proposed instrument and a faculty member does not)
If you are a Core Director and will be the PI for the NIH SIG proposal because a faculty member does not meet the criteria, please contact Jeanne Heschele at for instructions on obtaining a Rare Exception PI waiver so that you have time to request and obtain approval for the waiver so a copy of the request can be attached here.

5) For Resubmissions ONLY.
Please see the above section on “resubmission” under eligibility (about checking with your program officer and discussing the new requirement that this year, the PI must have documented evidence in your attached biosketch that you have the technical expertise that is directly related to the type of instrument chosen, and if, you’ll have to have someone who meets the criteria be the PI. If that PI is a Core Director, then that Core Director will need to contact me to obtain instructions for obtaining a “Rare Exception PI waiver” request. If you have the required expertise and want to “resubmit” your SIG proposal- for this internal vetting process you will:


Selection process
All of the Stanford University ORIG SIG proposals will be reviewed and vetted and will be notified about the status of the proposals as soon as possible after the internal vetting deadline

IMPORTANT NOTE: Shared Facility/Service Center Resources- Dean's office
You are encouraged to discuss shared facility, service center, core facility resources with Bruce Koch, Senior Director, Discovery and Technological Service Centers, Office of the Senior Associate Dean for Research at

Institutional Representative internal deadline:
You must be prepared to submit your proposals via eSubmit for your institutional representatives* at least 5-working days prior to the application receipt deadline. You are encouraged to notify your RPM as soon as possible that you will be submitting a proposal so he/she can begin to generate your budget and assist with other aspects of your application.
SoM Internal proposal submission policy change:

School of Medicine faculty: Research Process Manager (RPM) department assignments: more >>
Faculty in other schools: Download the Pre-award OSR department assignments on this DoResearch webpage >>

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