Doris Duke Charitable Foundation
Doris Duke Distinguished Clinical Scientist Award
for Excellence in "Bench to Bedside" Research
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The Distinguished Clinical Scientist award is only offered every other year. Therefore, this webpage contains information for the your reference only. The next internal selection process will be announced in the fall of 2010.
The complete announcement is available for downloading from the sponsor's
website
Internal deadline: Nov 2009 TBA
(see internal submission requirements)
Number of applicants
Two (internal
selection process required-see internal submission
requestions )
Amount of funding
Awards of $1.5 million will be made to as many as five outstanding physician-scientists
(M.D.s) conducting "bench to bedside" (translational) clinical research.
Highlights from the program announcement (including eligibility):
Purpose of Program
If today's biomedical breakthroughs are going to result in improved health, it is vital that the gap between biomedical advances and clinical application is bridged. The Distinguished Clinical Scientist Award (DCSA) Program is designed to support outstanding individuals and their teams who are bridging this gap.
The purpose of this award is to recognize and support outstanding mid-career physician-scientists who are engaged in applying basic biomedical advances to the prevention, diagnosis, treatment, and cure of any disease. The award provides funds to conduct translational clinical research as well as support and mentor more junior translational researchers working in the awardee's laboratory.
If todayÕs biomedical breakthroughs are going to result in improved health, it is vital that the gap between basic biomedical research and clinical research is bridged. This award is designed to support outstanding individuals and their teams that are bridging this gap.
- This program is specifically intended to support physician-scientists who are recognized leaders in their fields and who have well-established translational research programs.
- Nominees must have received a M.D. degree from an accredited institution. Holders of M.D./Ph.D. degrees are also eligible, as are holders of M.D.-equivalent degrees from non-US institutions.
- Be working in a U.S. degree-granting institution but do not have to be a U.S. citizen
- Nominees must have a full-time university faculty appointment at the level of associate professor or its equivalent by Jan. 1, 2008.
- Nominees must have been appointed to their first full time faculty-level position no earlier than Jan. 1, 1993. (Per the Doris Duke Charitable Foundation FAQs: "All full-time post-fellowship Instructor-level positions will be considered full-time faculty-level appointments." So for purposes of this RFA, you must include the the time spent in your Instructor position when making this calculation.
- The Foundation requires that the physician-scientist has an active translational clinical research program with demonstrated ability to lead a program.
- The individual must plan to devote a minimum of 75% of professional time to research (which can be a combination of basic and clinical).
- The DCSA is intended to support an original clinical research project that does not overlap projects funded by other sources of support. The planned research should apply biomedical advances to the prevention, diagnosis, treatment, or cure of disease. At least 30% of the Distinguished Clinical Scientist's total effort should be dedicated to the work proposed in the application.
- Each applicant must have a proven track record as an outstanding mentor to junior clinical investigators, including medical students, fellows, and junior faculty members. Given that one of the Foundation's main objectives is to support physician scientists, a majority of the mentees to be supported by the DCSA should be working on or hold an M.D..
**Note: Experiments that utilize animals will not be supported.**
Definition of Clinical Research
For the purposes of this program, clinical research is defined as research
conducted with human subjects or material of human origin in which
the principal investigator (or a colleague) directly interacts with
human subjects. The FoundationÕs definition of clinical research specifically includes:
- Studies on the etiology and pathogenesis of these diseases in man.
- Therapeutic interventions.
- Clinical trials.
- Epidemiological studies.
- Disease control research
- Operations and implementation research
Criteria for Review and Selection of Candidates
*Evidence of the applicant's outstanding record of achievement in clinical research and ability to apply advances in basic research to clinical problems.
*Evidence of a successful, ongoing research program with peer-reviewed funding.
*Quality and originality of the applicant's clinical research program.
*Importance of the research to the field.
*Appropriateness of the scope of the project and the methodology.
*Commitment of the applicant to mentoring junior physician-scientists in translational clinical research.
*Quality of the proposed plans to to mentor young investigators.
By Nov. 13, 2007 please deliver the one original and 10 sets of copies (in the order listed below) to:
Jeanne Heschele, jheschele@stanford.edu
Research Management Group,
1215 Welch Road, Mod. B, Room 46 (next to MSOB)
Phone 498-6845
1) Nomination letter printed on your department letterhead and addressed to Dr. Michael Cleary and the School of Medicine Awards Committee signed by your Division Chief and the Department Chair which describes:
--the nominee's key research accomplishments and ability to apply biomedical advances to clinical problems
--quality and originality of the applicant's proposed clinical research project and its importance to the field
--mentoring activities (especially mentoring junior investigators in translational clinical research)
what the Doris Duke Distinguished Clinical Scientist award would enable them to do
2) A list of 3 of the nominee's most significant peer-reviewed, translational clinical research publications--include the complete citation and ABSTRACT only for each publication (do not attach any reprints or include additional citations).
3) Research proposal (limit to 4 pages) illustrations and references are not included in the page total: include specific aims, background, preliminary results, research design and methods)
4) Biosketch or CV (limit to 3 pages)
5) Other funding---pending and current, with amount of funding, term, sponsor
These proposals will be submitted to the School of Medicine Awards Committee members for their review.
