Research Management Group (RMG)

Burroughs Wellcome Fund
Investigators in Pathogenesis of Infectious Disease

***$500K limited submission funding opportunity for assistant professors with UTL and MCL faculty appointments with established record of independent research (see eligibility). The School of Medicine will facilitate the selection process for the university per the internal submission guidelines below. ***

Revised eligibility (see below >>)

Internal Deadline: Monday, Sept. 15, 2014, 4 p.m. (see internal submission guidelines below)
Sponsor: Nov. 3, 2014
The awards will begin on July 1, 2015

Amount of Funding: $500,000 over a period of five years ($100,000 per year).

# of applicants permitted: 2-4*
*To encourage applications from veterinarians, institutions that nominate a researcher who holds the D.V.M. will be allowed three nominations. Institutions may have a single additional nomination if they nominate a researcher working in pathogenic helminths, mycology, or reproductive science.

Sponsor's website:

Please read: FAQ wepage:

Previous recipients:
Stanford recipients in 2011, 2009, 2005

Eligibility (REVISED):


Five-year awards provide $500,000 for opportunities for accomplished investigators at the assistant professor level to bring multidisciplinary approaches to the study of human infectious diseases.

The goal of the program is to provide opportunities for accomplished investigators still early in their careers to study what happens at the points where human and microbial systems connect. The program supports research that sheds light on the fundamentals that affect the outcomes of this encounter: how colonization, infection, commensalism and other relationships play out at levels ranging from molecular interactions to systemic ones. Studies supported by the program may have their roots in pathogen or host biology but the focus of the work should be on the interplay of host and microbe.

The program emphasizes research that opens up unexplored areas. Research on under-studied infectious diseases, including pathogenic fungi, protozoan and metazoan diseases, and emerging infections is especially of interest. In addition, excellent animal models of human disease, including work done in veterinary research settings, are within the program’s scope. Interdisciplinary approaches are encouraged.

The awards are intended to give recipients the freedom and flexibility to pursue high-risk projects and new avenues of inquiry. Work supported will be efforts that have the potential to significantly advance the understanding of how microbes and the human system interact, especially in the context of infection. Biochemical, pharmacological, molecular, genetic, immunologic, and other approaches are all appropriate for support by the program.


Areas of particular interest include:

Approaches that fit into these frameworks might include the study of host susceptibility to particular pathogens, host resistance to chronic or acute disease, or basic studies of infectious microbes—as long as the work is oriented toward understanding how the organism interacts with the host. Virulence factors, immune mechanisms, and genetic studies in microbes and the host all provide fertile ground for this kind of study.

Nominating institutions should note that research on under-funded and under-studied organisms is especially of interest: proposed work in well-funded systems may be viewed as less relevant to the program’s goals.


Selection is based on a number of factors, including:

Internal Submission Guidelines:

By Monday, Sept. 15, 2014, 4 p.m., please submit the following in one PDF file (in the order listed below) to

Jeanne Heschele
Research Management Group (RMG)

PDF file name: LAST NAME_BWF_Patho.pdf

Note: You do not have to submit an electronic PDRF form or involve your institutional representative for the internal selection process.

1) Title Page
Name of this RFA: Burroughs Wellcome Fund Investigators in Pathogenesis of Infectious Disease
Title of your proposal:
Indicate one of the following if your research involves: pathogenic helminths, mycology, or reproductive science. (The university will get an additional applicant slot, if one of the top ranked candidate's research is involved in one of these three areas.)
PI name, title, contact information (email, phone #)
*Permanent residents: you do not have to provide a copy of your green card with this internal proposal packet, simply indicate you are a permanent resident.

2) Nomination letter on your department's letterhead, signed by your division chief or your department chair addressed to Dr. Peter Sarnow and the School of Medicine Awards Committee: Please include references to the following:
candidate's qualifications and potential to conduct innovative research and the quality and originality of the proposed research and its potential to advance understanding of fundamental issues of how infectious agents and human hosts interact.
Please confirm the department will assure protection of 75 percent of the grantee's time for research-related activities.
Because the institution is provided an additional applicant slot for candidates involved in pathogenic helminths, mycology, or reproductive science, please identify in the first paragraph if the nominee's research involves those areas.

3) up to 4 page Research proposal (illustrations and references are not included in this page total. You may imbed your figures within the proposal as long as the text does not exceed four pages.)
Format: 1/2 inch margins, single-spaced, Arial or Helvetica font size 11 or larger

4) Biosketch

5) List of current and pending funding (include sponsor, term, and amount of funding)

Selection process:
The School of Medicine Awards Committee will review the proposals and select the final applicants to represent the university by the Nov. 3, 2014 deadline.











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