Stanford Center for Cancer Nanotechnology Excellence Focused on Therapy Response (CCNE-TR)
Research Projects-Collaborative Efforts for Renewal of a U54 Center Grant
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*Internal Funding Opportunity for Stanford faculty*
CCNE-TR website
Internal Deadline: Wed., April 1, 2009
(see Submitting an Application below)
Amount of Funding:
Applicants may request up to $200,000 in total direct costs for one year. This renewal CCNE grant has a cycle of 5 years. Thus, the applicant may request $1,000,000 in total direct costs for 5 years.
Eligibility:
Established investigators (Stanford faculty with UTL, MCL or NTLR appointments). Collaborations between at least two primary investigators with different disciplinary expertise are mandatory. Ideal interdisciplinary teams for this purpose should be formed from engineering, applied science, biology and medicine.
All applications, regardless of relationship to the CCNE-TR, will undergo the same level of scrutiny before being identified as an appropriate Research Project.
Contact information:
Applicants are welcome to discuss their plans in response to this solicitation. Please direct these inquiries to Billie Robles at brobles@stanford.edu.
Purpose:
CCNE-TR is soliciting new and continuing research projects (RO1 equivalent) from established investigators to collaborate with and join the efforts in submitting a renewal for the Stanford U54 CCNE grant. Up to 6 research projects will be selected. Those selected will then be required to write up their entire research proposal (aims, preliminary data, etc.) that will be submitted along with the entire CCNE grant renewal application by August 1, 2009. Center grants offer a greater opportunity for scientific interactions and overall progress than with individually-funded projects. Details of previously funded projects can be found at the website above.
The vision of CCNE-TR is to bring together researchers from diverse disciplines to form synergistic teams that will make significant advances in the creation of novel nanotechnology-based concepts and tools along with the use of existing nanotechnologies in the area of cancers. Members of these teams will include trainees that will gain access to a highly multidisciplinary experience, and who will become well equipped to establish independent, multidisciplinary research programs. Projects will mainly include those that have a high potential for clinical translation for improved cancer detection, staging, therapy response monitoring, theragnostics and many other aspects of cancer clinical management. Priority will be given to projects that have at least one specific aim that is focused on a clinical application. Projects must have a direct cancer focus. This program will be funded through the NIH/NCI U54 grant.
Examples of possible research projects include but are not limited to:
1- Development of novel nanodevices and concepts that can be used for cancer diagnostics and theragnostics. At this stage, we are not seeking proposals exclusively focusing on therapy alone.
2- Development of novel molecular imaging agents for any imaging modality that can be translated into a clinical trial as a part of the specific aims.
3- New or existing but promising diagnostic imaging technologies.
4. Biomolecule capture, concentration and separation technologies that are based on micro- to nanoscale components.
5. Novel or existing but promising bioanalyte capture technologies that can be used at micro- to nanoscale.
6- Other projects related to cancer nanotechnologies.
Note: Cancer nanotechnology research projects with strong clinical translational components or clinical developmental plans are strongly encouraged and will be given higher priority during the selection process. There is no single proposal restriction and submission of multiple proposals with distinct scientific themes is strongly encouraged.
Submitting an Application
Deadline: Wed. April 1, 2009 12 p.m.
Applicants should submit one electronic copy as an e-mail attachment in PDF format of the following to Billie Robles in the Radiology Department at brobles@stanford.edu by the deadline above.
Proposal Guidelines:
***Note: you do not need an SU-42 or to work with your RPM when preparing your proposal for this internal selection process.**
1) Title page with the following information:
Project title
Project leader's name, title, department, and complete contact information
Co-Investigators: names, titles, department affiliation, complete contact information
2) Description of proposed research, including the following:
2-3 pages executive summary with research plan, proposed aims, preliminary data, brief methods, and significance of potential research projects. (Note: illustrations, figure legends, and references are not included in the 2-3 page limit).
Also include a brief description of research subjects involved (both human or animal). A description of interdisciplinary characteristics of this project as it utilizes Specialized Resources. Explanation of how the proposed research fits into existing CCNE-TR Projects or potential research topics of interest to CCNE-TR as described above.
For resource and grant description see the CCNE-TR website
3) Detailed budget of up to $200,000 in total directs at applicable rates.
4) Budget Justification (NIH format)
5) Biosketch (NIH format) for the Project Leader and Co-Investigators.
6) Other Support (also NIH format). Please include both active and pending support.
Selection Process
The CCNE-TR Executive Committee will review and recommend action on all Research Project applications. All applications for Research Projects will be sent to Billie Robles brobles@stanford.edu including newly initiated projects as well as renewal projects. You will receive a notification of our selection by April 16, 2009.
Note: Selected applicants must provide verification of the recipient's human subject, SCRO and animal subject approvals and compliance with other administrative issue
Inquiries/Contact Person
Applicants are welcome to discuss their plans in response to this solicitation. Please direct all inquiries to Billie Robles at brobles@stanford.edu.
