Publications
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Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells.
Lan F,
Lee AS, Liang P, Sanchez-Freire V, Nguyen PK, Wang L, Han L, Yen M, Wang Y, Sun N, Abilez OJ, Hu S, Ebert AD, Navarrete EG, Simmons CS, Wheeler M, Pruitt B, Lewis R, Yamaguchi Y, Ashley EA, Bers DM, Robbins RC, Longaker MT, Wu JC.
Cell Stem Cell.
2013;
12
(1):
101-13
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Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
Liang P,
Lan F, Lee AS, Gong T, Sanchez-Freire V, Wang Y, Diecke S, Sallam K, Knowles JW, Wang PJ, Nguyen PK, Bers DM, Robbins RC, Wu JC.
Circulation.
2013;
127
(16):
1677-91
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Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.
Sun N,
Yazawa M, Liu J, Han L, Sanchez-Freire V, Abilez OJ, Navarrete EG, Hu S, Wang L, Lee A, Pavlovic A, Lin S, Chen R, Hajjar RJ, Snyder MP, Dolmetsch RE, Butte MJ, Ashley EA, Longaker MT, Robbins RC, Wu JC.
Sci Transl Med.
2012;
4
(130):
130ra47
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Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming.
Burridge PW,
Keller G, Gold JD, Wu JC.
Cell Stem Cell.
2012;
10
(1):
16-28
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An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells.
Tang C,
Lee AS, Volkmer JP, Sahoo D, Nag D, Mosley AR, Inlay MA, Ardehali R, Chavez SL, Pera RR, Behr B, Wu JC, Weissman IL, Drukker M.
Nat Biotechnol.
2011;
29
(9):
829-34
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Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells.
Pearl JI,
Lee AS, Leveson-Gower DB, Sun N, Ghosh Z, Lan F, Ransohoff J, Negrin RS, Davis MM, Wu JC.
Cell Stem Cell.
2011;
8
(3):
309-17
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Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells.
Narsinh KH,
Sun N, Sanchez-Freire V, Lee AS, Almeida P, Hu S, Jan T, Wilson KD, Leong D, Rosenberg J, Yao M, Robbins RC, Wu JC.
J Clin Invest.
2011;
121
(3):
1217-21
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A review of human pluripotent stem cell-derived cardiomyocytes for high-throughput drug discovery, cardiotoxicity screening, and publication standards.
Mordwinkin NM,
Burridge PW, Wu JC.
J Cardiovasc Transl Res.
2013;
6
(1):
22-30
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Advances in nanotechnology for the management of coronary artery disease.
Rhee JW,
Wu JC.
Trends Cardiovasc Med.
2013;
23
(2):
39-45
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Dissecting the molecular relationship among various cardiogenic progenitor cells.
Dey D,
Han L, Bauer M, Sanada F, Oikonomopoulos A, Hosoda T, Unno K, De Almeida P, Leri A, Wu JC.
Circ Res.
2013;
112
(9):
1253-62
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Effective delivery of stem cells using an extracellular matrix patch results in increased cell survival and proliferation and reduced scarring in skin wound healing.
Lam MT,
Nauta A, Meyer NP, Wu JC, Longaker MT.
Tissue Eng Part A.
2013;
19
(5-6):
738-47
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Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42).
Rajadas J,
Sun W, Li H, Inayathullah M, Cereghetti D, Tan A, de Mello Coelho V, Chrest FJ, Kusiak JW, Smith WW, Taub D, Wu JC, Rifkind JM.
PLoS One.
2013;
8
(3):
e58194
-
Immunogenicity of pluripotent stem cells and their derivatives.
de Almeida PE,
Ransohoff JD, Nahid A, Wu JC.
Circ Res.
2013;
112
(3):
549-61
-
Induced pluripotency of human prostatic epithelial cells.
Zhao H,
Sun N, Young SR, Nolley R, Santos J, Wu JC, Peehl DM.
PLoS One.
2013;
8
(5):
e64503
-
MicroRNA expression profiling of human-induced pluripotent and embryonic stem cells.
Sharma A,
Wu JC.
Methods Mol Biol.
2013:
936
247-56
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MicroRNA-302 increases reprogramming efficiency via repression of NR2F2.
Hu S,
Wilson KD, Ghosh Z, Han L, Wang Y, Lan F, Ransohoff KJ, Burridge P, Wu JC.
Stem Cells.
2013;
31
(2):
259-68
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Molecular imaging: The key to advancing cardiac stem cell therapy.
Chen IY,
Wu JC.
Trends Cardiovasc Med.
2013
-
Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases.
Churko JM,
Mantalas GL, Snyder MP, Wu JC.
Circ Res.
2013;
112
(12):
1613-23
-
Role of SIRT6 in Aging and Reprogramming of Human Induced Pluripotent Stem Cells.
Sharma A,
Diecke S, Zhang WY, Lan F, He C, Mordwinkin NM, Chua KF, Wu JC.
J Biol Chem.
2013
-
Sacrificial layer technique for axial force post assay of immature cardiomyocytes.
Taylor RE,
Kim K, Sun N, Park SJ, Sim JY, Fajardo G, Bernstein D, Wu JC, Pruitt BL.
Biomed Microdevices.
2013;
15
(1):
171-81
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Stem cell isolation: Differential stickiness.
Abilez OJ,
Wu JC.
Nat Mater.
2013;
12
(6):
474-6
-
Atomic force mechanobiology of pluripotent stem cell-derived cardiomyocytes.
Liu J,
Sun N, Bruce MA, Wu JC, Butte MJ.
PLoS One.
2012;
7
(5):
e37559
-
Biomaterial applications in cardiovascular tissue repair and regeneration.
Lam MT,
Wu JC.
Expert Rev Cardiovasc Ther.
2012;
10
(8):
1039-49
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Dynamic microRNA expression during the transition from right ventricular hypertrophy to failure.
Reddy S,
Zhao M, Hu DQ, Fajardo G, Hu S, Ghosh Z, Rajagopalan V, Wu JC, Bernstein D.
Physiol Genomics.
2012;
44
(10):
562-75
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Early stem cell engraftment predicts late cardiac functional recovery: preclinical insights from molecular imaging.
Liu J,
Narsinh KH, Lan F, Wang L, Nguyen PK, Hu S, Lee A, Han L, Gong Y, Huang M, Nag D, Rosenberg J, Chouldechova A, Robbins RC, Wu JC.
Circ Cardiovasc Imaging.
2012;
5
(4):
481-90
-
Enhancement of human adipose-derived stromal cell angiogenesis through knockdown of a BMP-2 inhibitor.
Levi B,
Nelson ER, Hyun JS, Glotzbach JP, Li S, Nauta A, Montoro DT, Lee M, Commons GC, Hu S, Wu JC, Gurtner GC, Longaker MT.
Plast Reconstr Surg.
2012;
129
(1):
53-66
-
Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging.
Wang Y,
Zhang WY, Hu S, Lan F, Lee AS, Huber B, Lisowski L, Liang P, Huang M, de Almeida PE, Won JH, Sun N, Robbins RC, Kay MA, Urnov FD, Wu JC.
Circ Res.
2012;
111
(12):
1494-503
-
Imaging stem cell therapy for the treatment of peripheral arterial disease.
Ransohoff JD,
Wu JC.
Curr Vasc Pharmacol.
2012;
10
(3):
361-73
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In Vivo Molecular Imaging of Murine Embryonic Stem Cells Delivered to a Burn Wound Surface via Integra® Scaffolding.
Hamrahi VF,
Goverman J, Jung W, Wu JC, Fischman AJ, Tompkins RG, Yu YY, Fagan SP, Carter EA.
J Burn Care Res.
2012;
33
(2):
e49-e54
-
In vivo directed differentiation of pluripotent stem cells for skeletal regeneration.
Levi B,
Hyun JS, Montoro DT, Lo DD, Chan CK, Hu S, Sun N, Lee M, Grova M, Connolly AJ, Wu JC, Gurtner GC, Weissman IL, Wan DC, Longaker MT.
Proc Natl Acad Sci U S A.
2012;
109
(50):
20379-84
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In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium.
Sheikh AY,
Huber BC, Narsinh KH, Spin JM, van der Bogt K, de Almeida PE, Ransohoff KJ, Kraft DL, Fajardo G, Ardigo D, Ransohoff J, Bernstein D, Fischbein MP, Robbins RC, Wu JC.
Arterioscler Thromb Vasc Biol.
2012;
32
(1):
92-102
-
Induced pluripotent stem cells as a disease modeling and drug screening platform.
Ebert AD,
Liang P, Wu JC.
J Cardiovasc Pharmacol.
2012;
60
(4):
408-16
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Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5.
Chen JX,
Krane M, Deutsch MA, Wang L, Rav-Acha M, Gregoire S, Engels MC, Rajarajan K, Karra R, Abel ED, Wu JC, Milan D, Wu SM.
Circ Res.
2012;
111
(1):
50-5
-
Large animal induced pluripotent stem cells as pre-clinical models for studying human disease.
Plews JR,
Gu M, Longaker MT, Wu JC.
J Cell Mol Med.
2012;
16
(6):
1196-202
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Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns.
Sanchez-Freire V,
Ebert AD, Kalisky T, Quake SR, Wu JC.
Nat Protoc.
2012;
7
(5):
829-38
-
Molecular imaging of bone marrow mononuclear cell survival and homing in murine peripheral artery disease.
van der Bogt KE,
Hellingman AA, Lijkwan MA, Bos EJ, de Vries MR, van Rappard JR, Fischbein MP, Quax PH, Robbins RC, Hamming JF, Wu JC.
JACC Cardiovasc Imaging.
2012;
5
(1):
46-55
-
Pluripotent stem cells: immune to the immune system?
Pearl JI,
Kean LS, Davis MM, Wu JC.
Sci Transl Med.
2012;
4
(164):
164ps25
-
Pushing the reset button: chemical-induced conversion of amniotic fluid stem cells into a pluripotent state.
Diecke S,
Wu JC.
Mol Ther.
2012;
20
(10):
1839-41
-
Returns of the living dead: therapeutic action of irradiated and mitotically inactivated embryonic stem cells.
Gold JD,
Wu JC.
Circ Res.
2012;
111
(10):
1250-2
-
Safe genetic modification of cardiac stem cells using a site-specific integration technique.
Lan F,
Liu J, Narsinh KH, Hu S, Han L, Lee AS, Karow M, Nguyen PK, Nag D, Calos MP, Robbins RC, Wu JC.
Circulation.
2012;
126
(11 Suppl 1):
S20-8
-
The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles.
Jang ES,
Shin JH, Ren G, Park MJ, Cheng K, Chen X, Wu JC, Sunwoo JB, Cheng Z.
Biomaterials.
2012;
33
(22):
5584-92
-
Transient, inducible, placenta-specific gene expression in mice.
Fan X,
Petitt M, Gamboa M, Huang M, Dhal S, Druzin ML, Wu JC, Chen-Tsai Y, Nayak NR.
Endocrinology.
2012;
153
(11):
5637-44
-
Cardiovascular molecular imaging: focus on clinical translation.
Chen IY,
Wu JC.
Circulation.
2011;
123
(4):
425-43
-
Comparison of human induced pluripotent and embryonic stem cells: fraternal or identical twins?
Narsinh KH,
Plews J, Wu JC.
Mol Ther.
2011;
19
(4):
635-8
-
Derivation of human induced pluripotent stem cells for cardiovascular disease modeling.
Narsinh K,
Narsinh KH, Wu JC.
Circ Res.
2011;
108
(9):
1146-56
-
Differences in osteogenic differentiation of adipose-derived stromal cells from murine, canine, and human sources in vitro and in vivo.
Levi B,
Nelson ER, Brown K, James AW, Xu D, Dunlevie R, Wu JC, Lee M, Wu B, Commons GW, Vistnes D, Longaker MT.
Plast Reconstr Surg.
2011;
128
(2):
373-86
-
Dissecting the oncogenic and tumorigenic potential of differentiated human induced pluripotent stem cells and human embryonic stem cells.
Ghosh Z,
Huang M, Hu S, Wilson KD, Dey D, Wu JC.
Cancer Res.
2011;
71
(14):
5030-9
-
Double knockdown of prolyl hydroxylase and factor-inhibiting hypoxia-inducible factor with nonviral minicircle gene therapy enhances stem cell mobilization and angiogenesis after myocardial infarction.
Huang M,
Nguyen P, Jia F, Hu S, Gong Y, de Almeida PE, Wang L, Nag D, Kay MA, Giaccia AJ, Robbins RC, Wu JC.
Circulation.
2011;
124
(11 Suppl):
S46-54
-
Effects of long-term culture on human embryonic stem cell aging.
Xie X,
Hiona A, Lee AS, Cao F, Huang M, Li Z, Cherry A, Pei X, Wu JC.
Stem Cells Dev.
2011;
20
(1):
127-38
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Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid.
Dey D,
Inayathullah M, Lee AS, LeMieux MC, Zhang X, Wu Y, Nag D, De Almeida PE, Han L, Rajadas J, Wu JC.
Biomaterials.
2011;
32
(20):
4647-58
-
Elastic properties of induced pluripotent stem cells.
Hammerick KE,
Huang Z, Sun N, Lam MT, Prinz FB, Wu JC, Commons GW, Longaker MT.
Tissue Eng Part A.
2011;
17
(3-4):
495-502
-
Endothelial progenitor cells in cardiovascular disease and chronic inflammation: from biomarker to therapeutic agent.
Grisar JC,
Haddad F, Gomari FA, Wu JC.
Biomark Med.
2011;
5
(6):
731-44
-
Functional characterization and expression profiling of human induced pluripotent stem cell- and embryonic stem cell-derived endothelial cells.
Li Z,
Hu S, Ghosh Z, Han Z, Wu JC.
Stem Cells Dev.
2011;
20
(10):
1701-10
-
Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors.
Narsinh KH,
Jia F, Robbins RC, Kay MA, Longaker MT, Wu JC.
Nat Protoc.
2011;
6
(1):
78-88
-
Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells.
Panula S,
Medrano JV, Kee K, Bergström R, Nguyen HN, Byers B, Wilson KD, Wu JC, Simon C, Hovatta O, Reijo Pera RA.
Hum Mol Genet.
2011;
20
(4):
752-62
-
Imaging atherosclerosis with F18-fluorodeoxyglucose positron emission tomography: What are we actually seeing?
Wu JC,
Nguyen PK.
J Am Coll Cardiol.
2011;
58
(6):
615-7
-
Imaging cardiac stem cell therapy: translations to human clinical studies.
Zhang WY,
Ebert AD, Narula J, Wu JC.
J Cardiovasc Transl Res.
2011;
4
(4):
514-22
-
Imaging of embryonic stem cell migration in vivo.
Lee AS,
Wu JC.
Methods Mol Biol.
2011:
750
101-14
-
Imaging: guiding the clinical translation of cardiac stem cell therapy.
Nguyen PK,
Lan F, Wang Y, Wu JC.
Circ Res.
2011;
109
(8):
962-79
-
In vivo bioluminescence for tracking cell fate and function.
de Almeida PE,
van Rappard JR, Wu JC.
Am J Physiol Heart Circ Physiol.
2011;
301
(3):
H663-71
-
Molecular imaging of RNA interference therapy targeting PHD2 for treatment of myocardial ischemia.
Huang M,
Wu JC.
Methods Mol Biol.
2011:
709
211-21
-
Nonintegrating knockdown and customized scaffold design enhances human adipose-derived stem cells in skeletal repair.
Levi B,
Hyun JS, Nelson ER, Li S, Montoro DT, Wan DC, Jia FJ, Glotzbach JC, James AW, Lee M, Huang M, Quarto N, Gurtner GC, Wu JC, Longaker MT.
Stem Cells.
2011;
29
(12):
2018-29
-
Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation.
Hu S,
Huang M, Nguyen PK, Gong Y, Li Z, Jia F, Lan F, Liu J, Nag D, Robbins RC, Wu JC.
Circulation.
2011;
124
(11 Suppl):
S27-34
-
Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells.
Lee AS,
Xu D, Plews JR, Nguyen PK, Nag D, Lyons JK, Han L, Hu S, Lan F, Liu J, Huang M, Narsinh KH, Long CT, de Almeida PE, Levi B, Kooreman N, Bangs C, Pacharinsak C, Ikeno F, Yeung AC, Gambhir SS, Robbins RC, Longaker MT, Wu JC.
J Biol Chem.
2011;
286
(37):
32697-704
-
Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function.
Hiona A,
Lee AS, Nagendran J, Xie X, Connolly AJ, Robbins RC, Wu JC.
J Thorac Cardiovasc Surg.
2011;
142
(2):
396-403.e3
-
Radiation exposure from imaging tests: is there an increased cancer risk?
Nguyen PK,
Wu JC.
Expert Rev Cardiovasc Ther.
2011;
9
(2):
177-83
-
Response to Letter Regarding Article, "Dynamic MicroRNA Expression Programs During Cardiac Differentiation of Human Embryonic Stem Cells: Role for miR-499".
Wilson KD,
Wu JC.
Circ Cardiovasc Genet.
2011;
4
(1):
e4
-
Sex differences in the diagnostic evaluation of coronary artery disease.
Nguyen PK,
Nag D, Wu JC.
J Nucl Cardiol.
2011;
18
(1):
144-52
-
Site-specific recombinase strategy to create induced pluripotent stem cells efficiently with plasmid DNA.
Karow M,
Chavez CL, Farruggio AP, Geisinger JM, Keravala A, Jung WE, Lan F, Wu JC, Chen-Tsai Y, Calos MP.
Stem Cells.
2011;
29
(11):
1696-704
-
Comparison of gene-transfer efficiency in human embryonic stem cells.
Cao F,
Xie X, Gollan T, Zhao L, Narsinh K, Lee RJ, Wu JC.
Mol Imaging Biol.
2010 Jan-Feb;
12
(1):
15-24
-
A nonviral minicircle vector for deriving human iPS cells.
Jia F,
Wilson KD, Sun N, Gupta DM, Huang M, Li Z, Panetta NJ, Chen ZY, Robbins RC, Kay MA, Longaker MT, Wu JC.
Nat Methods.
2010;
7
(3):
197-9
-
Advances in cardiovascular molecular imaging for tracking stem cell therapy.
Ransohoff KJ,
Wu JC.
Thromb Haemost.
2010;
104
(1):
13-22
-
Current perspectives on imaging cardiac stem cell therapy.
Wu JC,
Abraham MR, Kraitchman DL.
J Nucl Med.
2010:
51 Suppl 1
128S-136S
-
Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells: role for miR-499.
Wilson KD,
Hu S, Venkatasubrahmanyam S, Fu JD, Sun N, Abilez OJ, Baugh JJ, Jia F, Ghosh Z, Li RA, Butte AJ, Wu JC.
Circ Cardiovasc Genet.
2010;
3
(5):
426-35
-
Effects of ionizing radiation on self-renewal and pluripotency of human embryonic stem cells.
Wilson KD,
Sun N, Huang M, Zhang WY, Lee AS, Li Z, Wang SX, Wu JC.
Cancer Res.
2010;
70
(13):
5539-48
-
Embryonic stem cell biology: insights from molecular imaging.
Sallam K,
Wu JC.
Methods Mol Biol.
2010:
660
185-99
-
Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion.
Huang NF,
Niiyama H, Peter C, De A, Natkunam Y, Fleissner F, Li Z, Rollins MD, Wu JC, Gambhir SS, Cooke JP.
Arterioscler Thromb Vasc Biol.
2010;
30
(5):
984-91
-
Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead.
Narsinh KH,
Wu JC.
Mol Ther.
2010;
18
(6):
1061-3
-
Human iPS cell-based therapy: considerations before clinical applications.
Sun N,
Longaker MT, Wu JC.
Cell Cycle.
2010;
9
(5):
880-5
-
Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury.
Daadi MM,
Davis AS, Arac A, Li Z, Maag AL, Bhatnagar R, Jiang K, Sun G, Wu JC, Steinberg GK.
Stroke.
2010;
41
(3):
516-23
-
Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy.
Chen IY,
Gheysens O, Ray S, Wang Q, Padmanabhan P, Paulmurugan R, Loening AM, Rodriguez-Porcel M, Willmann JK, Sheikh AY, Nielsen CH, Hoyt G, Contag CH, Robbins RC, Biswal S, Wu JC, Gambhir SS.
Gene Ther.
2010;
17
(7):
827-38
-
Methods to assess stem cell lineage, fate and function.
Nguyen PK,
Nag D, Wu JC.
Adv Drug Deliv Rev.
2010;
62
(12):
1175-86
-
MicroRNA-210 as a novel therapy for treatment of ischemic heart disease.
Hu S,
Huang M, Li Z, Jia F, Ghosh Z, Lijkwan MA, Fasanaro P, Sun N, Wang X, Martelli F, Robbins RC, Wu JC.
Circulation.
2010;
122
(11 Suppl):
S124-31
-
Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells.
Ghosh Z,
Wilson KD, Wu Y, Hu S, Quertermous T, Wu JC.
PLoS One.
2010;
5
(2):
e8975
-
Rosiglitazone increases myocardial glucose metabolism in insulin-resistant cardiomyopathy.
Kao DP,
Witteles RM, Quon A, Wu JC, Gambhir SS, Fowler MB.
J Am Coll Cardiol.
2010;
55
(9):
926-7
-
The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat.
Yu J,
Du KT, Fang Q, Gu Y, Mihardja SS, Sievers RE, Wu JC, Lee RJ.
Biomaterials.
2010;
31
(27):
7012-20
-
Timing of bone marrow cell delivery has minimal effects on cell viability and cardiac recovery after myocardial infarction.
Swijnenburg RJ,
Govaert JA, van der Bogt KE, Pearl JI, Huang M, Stein W, Hoyt G, Vogel H, Contag CH, Robbins RC, Wu JC.
Circ Cardiovasc Imaging.
2010;
3
(1):
77-85
-
Tumorigenicity of pluripotent stem cells: biological insights from molecular imaging.
Kooreman NG,
Wu JC.
J R Soc Interface.
2010:
7 Suppl 6
S753-63
-
Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation.
Chen IY,
Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS.
Mol Imaging Biol.
2009 May-Jun;
11
(3):
178-87
-
Bioluminescence reporter gene imaging of human embryonic stem cell survival, proliferation, and fate.
Wilson KD,
Huang M, Wu JC.
Methods Mol Biol.
2009:
574
87-103
-
Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart.
van der Bogt KE,
Schrepfer S, Yu J, Sheikh AY, Hoyt G, Govaert JA, Velotta JB, Contag CH, Robbins RC, Wu JC.
Transplantation.
2009;
87
(5):
642-52
-
Current-Controlled Electrical Point-Source Stimulation of Embryonic Stem Cells.
Chen MQ,
Xie X, Wilson KD, Sun N, Wu JC, Giovangrandi L, Kovacs GT.
Cell Mol Bioeng.
2009;
2
(4):
625-635
-
Effects of cell number on teratoma formation by human embryonic stem cells.
Lee AS,
Tang C, Cao F, Xie X, van der Bogt K, Hwang A, Connolly AJ, Robbins RC, Wu JC.
Cell Cycle.
2009;
8
(16):
2608-12
-
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells.
Sun N,
Panetta NJ, Gupta DM, Wilson KD, Lee A, Jia F, Hu S, Cherry AM, Robbins RC, Longaker MT, Wu JC.
Proc Natl Acad Sci U S A.
2009;
106
(37):
15720-5
-
Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction.
Li Z,
Wilson KD, Smith B, Kraft DL, Jia F, Huang M, Xie X, Robbins RC, Gambhir SS, Weissman IL, Wu JC.
PLoS One.
2009;
4
(12):
e8443
-
Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction.
Deuse T,
Peter C, Fedak PW, Doyle T, Reichenspurner H, Zimmermann WH, Eschenhagen T, Stein W, Wu JC, Robbins RC, Schrepfer S.
Circulation.
2009;
120
(11 Suppl):
S247-54
-
Imaging gene expression in human mesenchymal stem cells: from small to large animals.
Willmann JK,
Paulmurugan R, Rodriguez-Porcel M, Stein W, Brinton TJ, Connolly AJ, Nielsen CH, Lutz AM, Lyons J, Ikeno F, Suzuki Y, Rosenberg J, Chen IY, Wu JC, Yeung AC, Yock P, Robbins RC, Gambhir SS.
Radiology.
2009;
252
(1):
117-27
-
Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation.
Xie X,
Chan KS, Cao F, Huang M, Li Z, Lee A, Weissman IL, Wu JC.
Stem Cells Dev.
2009;
18
(2):
205-14
-
Imaging survival and function of transplanted cardiac resident stem cells.
Li Z,
Lee A, Huang M, Chun H, Chung J, Chu P, Hoyt G, Yang P, Rosenberg J, Robbins RC, Wu JC.
J Am Coll Cardiol.
2009;
53
(14):
1229-40
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Long term non-invasive imaging of embryonic stem cells using reporter genes.
Sun N,
Lee A, Wu JC.
Nat Protoc.
2009;
4
(8):
1192-201
-
MicroRNA profiling of human-induced pluripotent stem cells.
Wilson KD,
Venkatasubrahmanyam S, Jia F, Sun N, Butte AJ, Wu JC.
Stem Cells Dev.
2009;
18
(5):
749-58
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Modeling conduction in host-graft interactions between stem cell grafts and cardiomyocytes.
Chen MQ,
Yu J, Whittington RH, Wu JC, Kovacs GT, Giovangrandi L.
Conf Proc IEEE Eng Med Biol Soc.
2009:
2009
6014-7
-
Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain.
Daadi MM,
Li Z, Arac A, Grueter BA, Sofilos M, Malenka RC, Wu JC, Steinberg GK.
Mol Ther.
2009;
17
(7):
1282-91
-
Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation.
Cao F,
Li Z, Lee A, Liu Z, Chen K, Wang H, Cai W, Chen X, Wu JC.
Cancer Res.
2009;
69
(7):
2709-13
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Novel minicircle vector for gene therapy in murine myocardial infarction.
Huang M,
Chen Z, Hu S, Jia F, Li Z, Hoyt G, Robbins RC, Kay MA, Wu JC.
Circulation.
2009;
120
(11 Suppl):
S230-7
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Poor functional recovery after transplantation of diabetic bone marrow stem cells in ischemic myocardium.
Govaert JA,
Swijnenburg RJ, Schrepfer S, Xie X, van der Bogt KE, Hoyt G, Stein W, Ransohoff KJ, Robbins RC, Wu JC.
J Heart Lung Transplant.
2009;
28
(11):
1158-1165.e1
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Tracking cardiac engraftment and distribution of implanted bone marrow cells: Comparing intra-aortic, intravenous, and intramyocardial delivery.
Li SH,
Lai TY, Sun Z, Han M, Moriyama E, Wilson B, Fazel S, Weisel RD, Yau T, Wu JC, Li RK.
J Thorac Cardiovasc Surg.
2009;
137
(5):
1225-33.e1
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Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging.
Wang H,
Cao F, De A, Cao Y, Contag C, Gambhir SS, Wu JC, Chen X.
Stem Cells.
2009;
27
(7):
1548-58
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Transplantation of human embryonic stem cell-derived endothelial cells for vascular diseases.
Li Z,
Han Z, Wu JC.
J Cell Biochem.
2009;
106
(2):
194-9
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Can radionuclide imaging predict future response to stem cell therapy?
Wu JC,
J Nucl Cardiol.
2008 May-Jun;
15
(3):
308-10
-
A novel platform device for rodent echocardiography.
Kutschka I,
Sheikh AY, Sista R, Hendry SL, Chun HJ, Hoyt G, Kutschka W, Pelletier MP, Quertermous T, Wu JC, Robbins RC.
ILAR J.
2008:
49
E1-7
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Cardiac differentiation of embryonic stem cells with point-source electrical stimulation.
Chen MQ,
Xie X, Hollis Whittington R, Kovacs GT, Wu JC, Giovangrandi L.
Conf Proc IEEE Eng Med Biol Soc.
2008:
2008
1729-32
-
Comparison of different adult stem cell types for treatment of myocardial ischemia.
van der Bogt KE,
Sheikh AY, Schrepfer S, Hoyt G, Cao F, Ransohoff KJ, Swijnenburg RJ, Pearl J, Lee A, Fischbein M, Contag CH, Robbins RC, Wu JC.
Circulation.
2008;
118
(14 Suppl):
S121-9
-
Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects.
Li Z,
Suzuki Y, Huang M, Cao F, Xie X, Connolly AJ, Yang PC, Wu JC.
Stem Cells.
2008;
26
(4):
864-73
-
Imaging of VEGF receptor in a rat myocardial infarction model using PET.
Rodriguez-Porcel M,
Cai W, Gheysens O, Willmann JK, Chen K, Wang H, Chen IY, He L, Wu JC, Li ZB, Mohamedali KA, Kim S, Rosenblum MG, Chen X, Gambhir SS.
J Nucl Med.
2008;
49
(4):
667-73
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Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts.
Swijnenburg RJ,
Schrepfer S, Govaert JA, Cao F, Ransohoff K, Sheikh AY, Haddad M, Connolly AJ, Davis MM, Robbins RC, Wu JC.
Proc Natl Acad Sci U S A.
2008;
105
(35):
12991-6
-
In vitro and in vivo bioluminescence reporter gene imaging of human embryonic stem cells.
Wilson K,
Yu J, Lee A, Wu JC.
J Vis Exp.
2008;
(14)
-
In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation.
Swijnenburg RJ,
Schrepfer S, Cao F, Pearl JI, Xie X, Connolly AJ, Robbins RC, Wu JC.
Stem Cells Dev.
2008;
17
(6):
1023-9
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Intracellular and extracellular targets of molecular imaging in the myocardium.
Chun HJ,
Narula J, Hofstra L, Wu JC.
Nat Clin Pract Cardiovasc Med.
2008:
5 Suppl 2
S33-41
-
Molecular imaging: antidote to cardiac stem cell controversy.
Wu JC,
J Am Coll Cardiol.
2008;
52
(20):
1661-4
-
Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells.
Hendry SL,
van der Bogt KE, Sheikh AY, Arai T, Dylla SJ, Drukker M, McConnell MV, Kutschka I, Hoyt G, Cao F, Weissman IL, Connolly AJ, Pelletier MP, Wu JC, Robbins RC, Yang PC.
J Thorac Cardiovasc Surg.
2008;
136
(4):
1028-1037.e1
-
Noninvasive radionuclide imaging of cardiac gene therapy: progress and potential.
Hiona A,
Wu JC.
Nat Clin Pract Cardiovasc Med.
2008:
5 Suppl 2
S87-95
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Reporter gene imaging following percutaneous delivery in swine moving toward clinical applications.
Rodriguez-Porcel M,
Brinton TJ, Chen IY, Gheysens O, Lyons J, Ikeno F, Willmann JK, Wu L, Wu JC, Yeung AC, Yock P, Gambhir SS.
J Am Coll Cardiol.
2008;
51
(5):
595-7
-
Seeing is believing: tracking cells to determine the effects of cell transplantation.
Pearl J,
Wu JC.
Semin Thorac Cardiovasc Surg.
2008;
20
(2):
102-9
-
Shear stress influences spatial variations in vascular Mn-SOD expression: implication for LDL nitration.
Ai L,
Rouhanizadeh M, Wu JC, Takabe W, Yu H, Alavi M, Li R, Chu Y, Miller J, Heistad DD, Hsiai TK.
Am J Physiol Cell Physiol.
2008;
294
(6):
C1576-85
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Short hairpin RNA interference therapy for ischemic heart disease.
Huang M,
Chan DA, Jia F, Xie X, Li Z, Hoyt G, Robbins RC, Chen X, Giaccia AJ, Wu JC.
Circulation.
2008;
118
(14 Suppl):
S226-33
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Surgically palliated double-inlet left ventricle with transposition of the great arteries mistaken for aortic aneurysm with dissection.
Gupta A,
Fleischmann D, Murphy DJ, Wu JC.
Int J Cardiol.
2008;
128
(2):
e82-4
-
Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes.
Cao F,
Wagner RA, Wilson KD, Xie X, Fu JD, Drukker M, Lee A, Li RA, Gambhir SS, Weissman IL, Robbins RC, Wu JC.
PLoS One.
2008;
3
(10):
e3474
-
Transcriptome alteration in the diabetic heart by rosiglitazone: implications for cardiovascular mortality.
Wilson KD,
Li Z, Wagner R, Yue P, Tsao P, Nestorova G, Huang M, Hirschberg DL, Yock PG, Quertermous T, Wu JC.
PLoS One.
2008;
3
(7):
e2609
-
In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival.
Cao F,
Sadrzadeh Rafie AH, Abilez OJ, Wang H, Blundo JT, Pruitt B, Zarins C, Wu JC.
J Tissue Eng Regen Med.
2007 Nov-Dec;
1
(6):
465-8
-
An unusual cause of stroke from a left atrial mass.
Wu JC,
Fishbein MC, Child JS.
J Am Soc Echocardiogr.
2007;
20
(5):
537.e1-2
-
Cardiovascular molecular imaging.
Wu JC,
Bengel FM, Gambhir SS.
Radiology.
2007;
244
(2):
337-55
-
Clinical dilemmas in treating left ventricular thrombus.
Leeper NJ,
Gupta A, Schnittger I, Wu JC.
Int J Cardiol.
2007;
114
(3):
e118-9
-
Clinical hurdles for the transplantation of cardiomyocytes derived from human embryonic stem cells: role of molecular imaging.
Swijnenburg RJ,
van der Bogt KE, Sheikh AY, Cao F, Wu JC.
Curr Opin Biotechnol.
2007;
18
(1):
38-45
-
Comparison of imaging techniques for tracking cardiac stem cell therapy.
Zhang SJ,
Wu JC.
J Nucl Med.
2007;
48
(12):
1916-9
-
Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease.
Li Z,
Wu JC, Sheikh AY, Kraft D, Cao F, Xie X, Patel M, Gambhir SS, Robbins RC, Cooke JP, Wu JC.
Circulation.
2007;
116
(11 Suppl):
I46-54
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Genetic modification of embryonic stem cells with VEGF enhances cell survival and improves cardiac function.
Xie X,
Cao F, Sheikh AY, Li Z, Connolly AJ, Pei X, Li RK, Robbins RC, Wu JC.
Cloning Stem Cells.
2007;
9
(4):
549-63
-
Integration of genomics, proteomics, and imaging for cardiac stem cell therapy.
Chun HJ,
Wilson KO, Huang M, Wu JC.
Eur J Nucl Med Mol Imaging.
2007:
34 Suppl 1
S20-6
-
Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse.
Yue P,
Arai T, Terashima M, Sheikh AY, Cao F, Charo D, Hoyt G, Robbins RC, Ashley EA, Wu J, Yang PC, Tsao PS.
Am J Physiol Heart Circ Physiol.
2007;
292
(5):
H2106-18
-
Molecular imaging in cardiology.
Wu JC,
Narula J.
Curr Opin Biotechnol.
2007
-
Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium.
Sheikh AY,
Lin SA, Cao F, Cao Y, van der Bogt KE, Chu P, Chang CP, Contag CH, Robbins RC, Wu JC.
Stem Cells.
2007;
25
(10):
2677-84
-
Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation.
Cao F,
Drukker M, Lin S, Sheikh AY, Xie X, Li Z, Connolly AJ, Weissman IL, Wu JC.
Cloning Stem Cells.
2007;
9
(1):
107-17
-
Positron emission tomography imaging of conditional gene activation in the heart.
Chang GY,
Cao F, Krishnan M, Huang M, Li Z, Xie X, Sheikh AY, Hoyt G, Robbins RC, Hsiai T, Schneider MD, Wu JC.
J Mol Cell Cardiol.
2007;
43
(1):
18-26
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Quantum dot imaging for embryonic stem cells.
Lin S,
Xie X, Patel MR, Yang YH, Li Z, Cao F, Gheysens O, Zhang Y, Gambhir SS, Rao JH, Wu JC.
BMC Biotechnol.
2007:
7
67
-
Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation.
Cao F,
van der Bogt KE, Sadrzadeh A, Xie X, Sheikh AY, Wang H, Connolly AJ, Robbins RC, Wu JC.
Stem Cells Dev.
2007;
16
(6):
883-91
-
Noninvasive evaluation of immunosuppressive drug efficacy on acute donor cell survival.
Gheysens O,
Lin S, Cao F, Wang D, Chen IY, Rodriguez-Porcel M, Min JJ, Gambhir SS, Wu JC.
Mol Imaging Biol.
2006 May-Jun;
8
(3):
163-70
-
18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer.
Zhang X,
Cai W, Cao F, Schreibmann E, Wu Y, Wu JC, Xing L, Chen X.
J Nucl Med.
2006;
47
(3):
492-501
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Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging.
Krishnan M,
Park JM, Cao F, Wang D, Paulmurugan R, Tseng JR, Gonzalgo ML, Gambhir SS, Wu JC.
FASEB J.
2006;
20
(1):
106-8
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Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene.
Xiong Z,
Cheng Z, Zhang X, Patel M, Wu JC, Gambhir SS, Chen X.
J Nucl Med.
2006;
47
(1):
130-9
-
In vivo bioluminescence imaging of cord blood derived mesenchymal stem cell transplantation into rat myocardium.
Min JJ,
Ahn Y, Moon S, Kim YS, Park JE, Kim SM, Le UN, Wu JC, Joo SY, Hong MH, Yang DH, Jeong MH, Song CH, Jeong YH, Yoo KY, Kang KS, Bom HS.
Ann Nucl Med.
2006;
20
(3):
165-70
-
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery.
Cao F,
Lin S, Xie X, Ray P, Patel M, Zhang X, Drukker M, Dylla SJ, Connolly AJ, Chen X, Weissman IL, Gambhir SS, Wu JC.
Circulation.
2006;
113
(7):
1005-14
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Molecular imaging of cardiac stem cell transplantation.
Sheikh AY,
Wu JC.
Curr Cardiol Rep.
2006;
8
(2):
147-54
-
Molecular imaging of human embryonic stem cells: keeping an eye on differentiation, tumorigenicity and immunogenicity.
van der Bogt KE,
Swijnenburg RJ, Cao F, Wu JC.
Cell Cycle.
2006;
5
(23):
2748-52
-
Overview of stem cells and imaging modalities for cardiovascular diseases.
Chang GY,
Xie X, Wu JC.
J Nucl Cardiol.
2006;
13
(4):
554-69
-
Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells.
Wu JC,
Cao F, Dutta S, Xie X, Kim E, Chungfat N, Gambhir S, Mathewson S, Connolly AJ, Brown M, Wang EW.
Proteomics.
2006;
6
(23):
6234-49
-
Right coronary cameral fistula resulting from surgery of double chamber right ventricle.
Leeper NJ,
Gupta A, Murphy DJ, Wu JC.
J Am Soc Echocardiogr.
2006;
19
(9):
1191.e9-11
-
Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation.
Wu JC,
Spin JM, Cao F, Lin S, Xie X, Gheysens O, Chen IY, Sheikh AY, Robbins RC, Tsalenko A, Gambhir SS, Quertermous T.
Physiol Genomics.
2006;
25
(1):
29-38
-
Human gene therapy and imaging: cardiology.
Wu JC,
Yla-Herttuala S.
Eur J Nucl Med Mol Imaging.
2005:
32 Suppl 2
S346-57
-
Image-guided cardiac cell delivery using high-resolution small-animal ultrasound.
Rodriguez-Porcel M,
Gheysens O, Chen IY, Wu JC, Gambhir SS.
Mol Ther.
2005;
12
(6):
1142-7
-
Molecular imaging of cardiovascular gene products.
Wu JC,
Tseng JR, Gambhir SS.
J Nucl Cardiol.
2004 Jul-Aug;
11
(4):
491-505
-
Cardiac-specific gene expression facilitated by an enhanced myosin light chain promoter.
Boecker W,
Bernecker OY, Wu JC, Zhu X, Sawa T, Grazette L, Rosenzweig A, del Monte F, Schmidt U, Hajjar RJ.
Mol Imaging.
2004;
3
(2):
69-75
-
Common congenital heart disorders in adults.
Wu JC,
Child JS.
Curr Probl Cardiol.
2004;
29
(11):
641-700
-
Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery.
Chen IY,
Wu JC, Min JJ, Sundaresan G, Lewis X, Liang Q, Herschman HR, Gambhir SS.
Circulation.
2004;
109
(11):
1415-20
-
Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium.
Wu JC,
Chen IY, Wang Y, Tseng JR, Chhabra A, Salek M, Min JJ, Fishbein MC, Crystal R, Gambhir SS.
Circulation.
2004;
110
(6):
685-91
-
Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography.
Wu JC,
Chen IY, Sundaresan G, Min JJ, De A, Qiao JH, Fishbein MC, Gambhir SS.
Circulation.
2003;
108
(11):
1302-5
-
Positron-emission tomography reporter gene expression imaging in rat myocardium.
Inubushi M,
Wu JC, Gambhir SS, Sundaresan G, Satyamurthy N, Namavari M, Yee S, Barrio JR, Stout D, Chatziioannou AF, Wu L, Schelbert HR.
Circulation.
2003;
107
(2):
326-32
-
Optical imaging of cardiac reporter gene expression in living rats.
Wu JC,
Inubushi M, Sundaresan G, Schelbert HR, Gambhir SS.
Circulation.
2002;
105
(14):
1631-4
-
Positron emission tomography imaging of cardiac reporter gene expression in living rats.
Wu JC,
Inubushi M, Sundaresan G, Schelbert HR, Gambhir SS.
Circulation.
2002;
106
(2):
180-3
-
Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice.
Wu JC,
Sundaresan G, Iyer M, Gambhir SS.
Mol Ther.
2001;
4
(4):
297-306
-
Severe regional ischemia alters coronary flow reserve in the remote perfusion area.
Wu JC,
Yun JJ, Dione DP, Heller EN, Deckelbaum LI, Sinusas AJ.
J Nucl Cardiol.
2000 Jan-Feb;
7
(1):
43-52
-
Limitations of dobutamine for enhancing flow heterogeneity in the presence of single coronary stenosis: implications for technetium-99m-sestamibi imaging.
Wu JC,
Yun JJ, Heller EN, Dione DP, DeMan P, Liu YH, Zaret BL, Wackers FJ, Sinusas AJ.
J Nucl Med.
1998;
39
(3):
417-25
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