Miriam B. Goodman

Publications

• Bidirectional temperature-sensing by a single thermosensory neuron in C. elegans. Ramot D, MacInnis BL, Goodman MB. Nat Neurosci. 2008; 11 (8): 908-15
• Thermotaxis is a robust mechanism for thermoregulation in Caenorhabditis elegans nematodes. Ramot D, MacInnis BL, Lee HC, Goodman MB. J Neurosci. 2008; 28 (47): 12546-57
• Nanoscale organization of the MEC-4 DEG/ENaC sensory mechanotransduction channel in Caenorhabditis elegans touch receptor neurons. Cueva JG, Mulholland A, Goodman MB. J Neurosci. 2007; 27 (51): 14089-98
• Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade. Brown AL, Fernandez-Illescas SM, Liao Z, Goodman MB. J Gen Physiol. 2007; 129 (2): 161-73
• Analysis of nematode mechanics by piezoresistive displacement clamp. Park SJ, Goodman MB, Pruitt BL. Proc Natl Acad Sci U S A. 2007; 104 (44): 17376-81
• The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals. O'Hagan R, Chalfie M, Goodman MB. Nat Neurosci. 2005; 8 (1): 43-50
• SU-8 force sensing pillar arrays for biological measurements. Doll JC, Harjee N, Klejwa N, Kwon R, Coulthard SM, Petzold B, Goodman MB, Pruitt BL. Lab Chip. 2009; 9 (10): 1449-54
• Pressure-polishing pipettes for improved patch-clamp recording. Johnson BE, Brown AL, Goodman MB. J Vis Exp. 2008; (20)
• MEC-2 and MEC-6 in the Caenorhabditis elegans sensory mechanotransduction complex: auxiliary subunits that enable channel activity. Brown AL, Liao Z, Goodman MB. J Gen Physiol. 2008; 131 (6): 605-16
• The Parallel Worm Tracker: a platform for measuring average speed and drug-induced paralysis in nematodes. Ramot D, Johnson BE, Berry TL, Carnell L, Goodman MB. PLoS One. 2008; 3 (5): e2208
• Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans. Chalasani SH, Chronis N, Tsunozaki M, Gray JM, Ramot D, Goodman MB, Bargmann CI. Nature. 2007; 450 (7166): 63-70
• Mechanosensation. Goodman MB, WormBook. 2006: 1-14
• Eppendorf essay winner. Deconstructing C. elegans sensory mechanotransduction. Goodman MB, Science. 2004; 306 (5695): 427-8
• Molecules and mechanisms of mechanotransduction. Goodman MB, Lumpkin EA, Ricci A, Tracey WD, Kernan M, Nicolson T. J Neurosci. 2004; 24 (42): 9220-2
• Sensation is painless. Goodman MB, Trends Neurosci. 2003; 26 (12): 643-5
• Transducing touch in Caenorhabditis elegans. Goodman MB, Schwarz EM. Annu Rev Physiol. 2003: 65 429-52
• The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel. Chelur DS, Ernstrom GG, Goodman MB, Yao CA, Chen L, O' Hagan R, Chalfie M. Nature. 2002; 420 (6916): 669-73
• MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation. Goodman MB, Ernstrom GG, Chelur DS, O'Hagan R, Yao CA, Chalfie M. Nature. 2002; 415 (6875): 1039-42
• Pressure polishing: a method for re-shaping patch pipettes during fire polishing. Goodman MB, Lockery SR. J Neurosci Methods. 2000; 100 (1-2): 13-5
• Tight-seal whole-cell patch clamping of Caenorhabditis elegans neurons. Lockery SR, Goodman MB. Methods Enzymol. 1998: 293 201-17
• Active currents regulate sensitivity and dynamic range in C. elegans neurons. Goodman MB, Hall DH, Avery L, Lockery SR. Neuron. 1998; 20 (4): 763-72
• Positive feedback by a potassium-selective inward rectifier enhances tuning in vertebrate hair cells. Goodman MB, Art JJ. Biophys J. 1996; 71 (1): 430-42
• Ionic conductances and hair cell tuning in the turtle cochlea. Art JJ, Goodman MB. Ann N Y Acad Sci. 1996: 781 103-22
• Variations in the ensemble of potassium currents underlying resonance in turtle hair cells. Goodman MB, Art JJ. J Physiol. 1996: 497 ( Pt 2) 395-412
• A kinetic description of the calcium-activated potassium channel and its application to electrical tuning of hair cells. Wu YC, Art JJ, Goodman MB, Fettiplace R. Prog Biophys Mol Biol. 1995; 63 (2): 131-58
• Rapid scanning confocal microscopy. Art JJ, Goodman MB. Methods Cell Biol. 1993: 38 47-77
• Activation of the inositol trisphosphate second messenger system by cAMP in a mouse fibroblast cell line. Horn VJ, Sheehy PA, Goodman MB, Ambudkar IS. Mol Cell Biochem. 1991; 101 (1): 43-9
• Inositol trisphosphate mediates cloned muscarinic receptor-activated conductances in transfected mouse fibroblast A9 L cells. Jones SV, Barker JL, Goodman MB, Brann MR. J Physiol. 1990: 421 499-519
• Calcium currents and fura-2 signals in fluorescence-activated cell sorted lactotrophs and somatotrophs of rat anterior pituitary. Lewis DL, Goodman MB, St John PA, Barker JL. Endocrinology. 1988; 123 (1): 611-21