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Zijie SunAcademic Appointments
Appointment
Organization
Associate Professor
Associate Professor
Member
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Postdoctoral Advisees
Yue Peng
Research Interests
Transcriptional control is a key step in the regulation of eukaryotic gene expression. My laboratory focuses on understanding the molecular mechanism of transcription factors that govern the transformation of normal mammalian cells to neoplastic state. We are particularly interested in the action of nuclear hormone receptors and the interactions between the receptors and other signaling pathways during tumor development and progression. Our long-term goal is to identify new diagnostic and therapeutic strategies for human cancers.
Publications
- Verras M, Lee J, Xue H, Li TH, Wang Y, Sun Z "The androgen receptor negatively regulates the expression of c-Met: implications for a novel mechanism of prostate cancer progression." Cancer Res 2007; 67: 3: 967-75 More »
- Li TH, Zhao H, Peng Y, Beliakoff J, Brooks JD, Sun Z "A promoting role of androgen receptor in androgen-sensitive and -insensitive prostate cancer cells." Nucleic Acids Res 2007; More »
- Lee J, Beliakoff J, Sun Z "The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor." Nucleic Acids Res 2007; More »
- Beliakoff J, Lee J, Ueno H, Aiyer A, Weissman IL, Barsh GS, Cardiff RD, Sun Z "The PIAS-like Protein Zimp10 is Essential for Embryonic Viability and Proper Vascular Development." Mol Cell Biol 2007; More »
- Li X, Thyssen G, Beliakoff J, Sun Z "The novel PIAS-like protein HZIMP10 enhances Smad transcriptional activity." J Biol Chem 2006; More »
41 publications: view full list
