Linda M. Dairiki Shortliffe

Clinical Focus

• Cancer > Urologic Oncology
• Urology, Pediatric
• Pediatric Urology

Administrative Appointments

• Chair, Stanford University School of Medicine Department of Urology (1996 - present)
• Program Director, Pediatric Urology Fellowship (2006 - present)
• Chair, American Academy Pediatrics Urology Section (2007 - 2008)
• Member, Residency Review Committee (2003 - 2009)
• Past President, American Board of Urology (2006 - 2007)
View All 10administrative appointments of Linda Shortliffe

Honors and Awards

• Featured Physician http://www.nlm.nih.gov/changingthefaceofmedicine/physicians/biography_293.html, National Library of Medicine (2003-2005)
• Asian American Faculty Award, Stanford University Asian American Association (2008)
• Best Doctors in America, Woodward and White (1991-2, 1994-5, 1996-7)
• America's Top Doctors, Castle Connolly (2001- 2008)

Professional Education

Postdoctoral Advisees

Jens-Peter Volkmer

Graduate & Fellowship Program Affiliations

• Urology
• Pediatric Urology

Community & International Work

• First International WHO Consultation on Health Care Associated Infections in Urology (HCAIU) 
• Urologic Diseases in America 

Web Site Links

• National Library of Medicine web link

Industry Relationships

Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. View Full Information

Research Interests

The timing for intervention in hydronephrosis in the infant and child is poorly understood. The interaction between urinary tract pressures and renal tubular and glomerular changes have not been well outlined. Our group has been interested in trying to define the parameters that may be involved in obstructive and infectious uropathies. We are also examining the effect of hormones on the urinary tract. We are applying the results of these findings to identify factors that could be markers of renal dysfunction. We have also collaborated with faculty at the Lucas Magnetic Resonance Center to develop new techniques with which to identify obstructive hydronephrosis. We have examined:

1. The effect of urinary flow rates and bladder fullness on renal pelvic and bladder pressures.
2. The effect of urinary tract infection on bladder and renal pelvic pressures.
3. The effect of vesicoureteral reflux on renal pelvic pressures.
4. The effect of anticholinergic drugs on bladder and renal pelvic pressures.
5. The effect of partial obstruction on renal pelvic pressures.
6. Urinary antibodies and intestinal bladder augmentation.
7. Ultrafast magnetic resonance imaging in a hydronephrotic rat model
8. Pathologic effect of inflammation and pressure on the kidney

Publications

• Quantitative ultrasound renal parenchymal area correlates with renal volume and identifies reflux nephropathy. Wong IY, Copp HL, Clark CJ, Wu HY, Shortliffe LD. J Urol. 2009; 182 (4 Suppl): 1683-7
• The management of renal angiomyolipomas in a patient with tuberous sclerosis. Wong IY, Shortliffe LD. Nat Clin Pract Urol. 2009; 6 (3): 168-72
• Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Chan KS, Espinosa I, Chao M, Wong D, Ailles L, Diehn M, Gill H, Presti J, Chang HY, van de Rijn M, Shortliffe L, Weissman IL. Proc Natl Acad Sci U S A. 2009; 106 (33): 14016-21
• Top-Down Approach for Evaluation of Urinary Tract Infection. Wu HY, Shortliffe LD. Urology. 2009
• A case of ectopic dysplastic kidney and ectopic ureter diagnosed by MRI. Duong DT, Shortliffe LM. Nat Clin Pract Urol. 2008; 5 (11): 632-6