Surgery  

James Chang

Publication Details

  • Human flexor tendon tissue engineering: decellularization of human flexor tendons reduces immunogenicity in vivo.

    Raghavan SS, Woon CY, Kraus A, Megerle K, Choi MS, Pridgen BC, Pham H, Chang J. Tissue Eng Part A. 2012; 18 (7-8): 796-805

    In mutilating hand injuries, tissue engineered tendon grafts may provide a reconstructive solution. We have previously described a method to decellularize cadaveric human flexor tendons while preserving mechanical properties and biocompatibility. The purpose of this study is to evaluate the immunogenicity and strength of these grafts when implanted into an immunocompetent rat model.

    PubMedID: 22011137

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