Publications
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A vaccine directed to B cells and produced by cell-free protein synthesis generates potent antilymphoma immunity.
Ng PP,
Jia M, Patel KG, Brody JD, Swartz JR, Levy S, Levy R.
Proc Natl Acad Sci U S A.
2012;
109
(36):
14526-31
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Complementary costimulation of human T-cell subpopulations by cluster of differentiation 28 (CD28) and CD81.
Sagi Y,
Landrigan A, Levy R, Levy S.
Proc Natl Acad Sci U S A.
2012;
109
(5):
1613-8
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Self-antigen recognition by follicular lymphoma B-cell receptors.
Sachen KL,
Strohman MJ, Singletary J, Alizadeh AA, Kattah NH, Lossos C, Mellins ED, Levy S, Levy R.
Blood.
2012;
120
(20):
4182-90
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The CD19/CD81 complex physically interacts with CD38 but is not required to induce proliferation in mouse B lymphocytes.
Vences-Catalán F,
Rajapaksa R, Levy S, Santos-Argumedo L.
Immunology.
2012;
137
(1):
48-55
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A CpG-loaded tumor cell vaccine induces antitumor CD4+ T cells that are effective in adoptive therapy for large and established tumors.
Goldstein MJ,
Varghese B, Brody JD, Rajapaksa R, Kohrt H, Czerwinski DK, Levy S, Levy R.
Blood.
2011;
117
(1):
118-27
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Escherichia coli-based production of a tumor idiotype antibody fragment--tetanus toxin fragment C fusion protein vaccine for B cell lymphoma.
Patel KG,
Ng PP, Levy S, Levy R, Swartz JR.
Protein Expr Purif.
2011;
75
(1):
15-20
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CD81 protein is expressed at high levels in normal germinal center B cells and in subtypes of human lymphomas.
Luo RF,
Zhao S, Tibshirani R, Myklebust JH, Sanyal M, Fernandez R, Gratzinger D, Marinelli RJ, Lu ZS, Wong A, Levy R, Levy S, Natkunam Y.
Hum Pathol.
2010;
41
(2):
271-80
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Cell-free production of Gaussia princeps luciferase--antibody fragment bioconjugates for ex vivo detection of tumor cells.
Patel KG,
Ng PP, Kuo CC, Levy S, Levy R, Swartz JR.
Biochem Biophys Res Commun.
2009;
390
(3):
971-6
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Engagement of CD81 induces ezrin tyrosine phosphorylation and its cellular redistribution with filamentous actin.
Coffey GP,
Rajapaksa R, Liu R, Sharpe O, Kuo CC, Krauss SW, Sagi Y, Davis RE, Staudt LM, Sharman JP, Robinson WH, Levy S.
J Cell Sci.
2009;
122
(Pt 17):
3137-44
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Enhanced B cell activation in the absence of CD81.
Sanyal M,
Fernandez R, Levy S.
Int Immunol.
2009;
21
(11):
1225-37
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Generation of CD8+ T cell-mediated immunity against idiotype-negative lymphoma escapees.
Varghese B,
Widman A, Do J, Taidi B, Czerwinski DK, Timmerman J, Levy S, Levy R.
Blood.
2009;
114
(20):
4477-85
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Wiskott-Aldrich syndrome protein is an effector of Kit signaling.
Mani M,
Venkatasubrahmanyam S, Sanyal M, Levy S, Butte A, Weinberg K, Jahn T.
Blood.
2009;
114
(14):
2900-8
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Cell-free production of scFv fusion proteins: an efficient approach for personalized lymphoma vaccines.
Kanter G,
Yang J, Voloshin A, Levy S, Swartz JR, Levy R.
Blood.
2007;
109
(8):
3393-9
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Building of the tetraspanin web: distinct structural domains of CD81 function in different cellular compartments.
Shoham T,
Rajapaksa R, Kuo CC, Haimovich J, Levy S.
Mol Cell Biol.
2006;
26
(4):
1373-85
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Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation.
Natkunam Y,
Lossos IS, Taidi B, Zhao S, Lu X, Ding F, Hammer AS, Marafioti T, Byrne GE, Levy S, Warnke RA, Levy R.
Blood.
2005;
105
(10):
3979-86
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Kinetics of HCV envelope proteins' interaction with CD81 large extracellular loop.
Nakajima H,
Cocquerel L, Kiyokawa N, Fujimoto J, Levy S.
Biochem Biophys Res Commun.
2005;
328
(4):
1091-100
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Protein-protein interactions in the tetraspanin web.
Levy S,
Shoham T.
Physiology (Bethesda).
2005:
20
218-24
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The tetraspanin web modulates immune-signalling complexes.
Levy S,
Shoham T.
Nat Rev Immunol.
2005;
5
(2):
136-48
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CD81-dependent binding of hepatitis C virus E1E2 heterodimers.
Cocquerel L,
Kuo CC, Dubuisson J, Levy S.
J Virol.
2003;
77
(19):
10677-83
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Hepatitis C virus (HCV) and lymphomagenesis.
Weng WK,
Levy S.
Leuk Lymphoma.
2003;
44
(7):
1113-20
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Recognition of native hepatitis C virus E1E2 heterodimers by a human monoclonal antibody.
Cocquerel L,
Quinn ER, Flint M, Hadlock KG, Foung SK, Levy S.
J Virol.
2003;
77
(2):
1604-9
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The tetraspanin CD81 regulates the expression of CD19 during B cell development in a postendoplasmic reticulum compartment.
Shoham T,
Rajapaksa R, Boucheix C, Rubinstein E, Poe JC, Tedder TF, Levy S.
J Immunol.
2003;
171
(8):
4062-72
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Critical role of CD81 in cognate T-B cell interactions leading to Th2 responses.
Deng J,
Dekruyff RH, Freeman GJ, Umetsu DT, Levy S.
Int Immunol.
2002;
14
(5):
513-23
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Il-18 gene transfer by adenovirus prevents the development of and reverses established allergen-induced airway hyperreactivity.
Walter DM,
Wong CP, DeKruyff RH, Berry GJ, Levy S, Umetsu DT.
J Immunol.
2001;
166
(10):
6392-8
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Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection.
Auffermann-Gretzinger S,
Keeffe EB, Levy S.
Blood.
2001;
97
(10):
3171-6
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In search of hepatitis C virus receptor(s).
Flint M,
Quinn ER, Levy S.
Clin Liver Dis.
2001;
5
(4):
873-93
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The B-cell receptor of a hepatitis C virus (HCV)-associated non-Hodgkin lymphoma binds the viral E2 envelope protein, implicating HCV in lymphomagenesis.
Quinn ER,
Chan CH, Hadlock KG, Foung SK, Flint M, Levy S.
Blood.
2001;
98
(13):
3745-9
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V(H)1-69 gene is preferentially used by hepatitis C virus-associated B cell lymphomas and by normal B cells responding to the E2 viral antigen.
Chan CH,
Hadlock KG, Foung SK, Levy S.
Blood.
2001;
97
(4):
1023-6
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Vaccination with allergen-IL-18 fusion DNA protects against, and reverses established, airway hyperreactivity in a murine asthma model.
Maecker HT,
Hansen G, Walter DM, DeKruyff RH, Levy S, Umetsu DT.
J Immunol.
2001;
166
(2):
959-65
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Allergen-induced airway hyperreactivity is diminished in CD81-deficient mice.
Deng J,
Yeung VP, Tsitoura D, DeKruyff RH, Umetsu DT, Levy S.
J Immunol.
2000;
165
(9):
5054-61
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Differential expression of murine CD81 highlighted by new anti-mouse CD81 monoclonal antibodies.
Maecker HT,
Todd SC, Kim EC, Levy S.
Hybridoma.
2000;
19
(1):
15-22
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Human monoclonal antibodies that inhibit binding of hepatitis C virus E2 protein to CD81 and recognize conserved conformational epitopes.
Hadlock KG,
Lanford RE, Perkins S, Rowe J, Yang Q, Levy S, Pileri P, Abrignani S, Foung SK.
J Virol.
2000;
74
(22):
10407-16
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CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system.
Levy S,
Todd SC, Maecker HT.
Annu Rev Immunol.
1998:
16
89-109
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CD81 on B cells promotes interleukin 4 secretion and antibody production during T helper type 2 immune responses.
Maecker HT,
Do MS, Levy S.
Proc Natl Acad Sci U S A.
1998;
95
(5):
2458-62
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Cytotoxic T cell responses to DNA vaccination: dependence on antigen presentation via class II MHC.
Maecker HT,
Umetsu DT, DeKruyff RH, Levy S.
J Immunol.
1998;
161
(12):
6532-6
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Sequences and expression of six new members of the tetraspanin/TM4SF family.
Todd SC,
Doctor VS, Levy S.
Biochim Biophys Acta.
1998;
1399
(1):
101-4
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An ovalbumin-IL-12 fusion protein is more effective than ovalbumin plus free recombinant IL-12 in inducing a T helper cell type 1-dominated immune response and inhibiting antigen-specific IgE production.
Kim TS,
DeKruyff RH, Rupper R, Maecker HT, Levy S, Umetsu DT.
J Immunol.
1997;
158
(9):
4137-44
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DNA vaccination with cytokine fusion constructs biases the immune response to ovalbumin.
Maecker HT,
Umetsu DT, DeKruyff RH, Levy S.
Vaccine.
1997;
15
(15):
1687-96
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Idiotype vaccines for non-Hodgkin's lymphoma induce polyclonal immune responses that cover mutated tumor idiotypes: comparison of different vaccine formulations.
Caspar CB,
Levy S, Levy R.
Blood.
1997;
90
(9):
3699-706
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Normal lymphocyte development but delayed humoral immune response in CD81-null mice.
Maecker HT,
Levy S.
J Exp Med.
1997;
185
(8):
1505-10
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The tetraspanin superfamily: molecular facilitators.
Maecker HT,
Todd SC, Levy S.
FASEB J.
1997;
11
(6):
428-42
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A nine-amino acid peptide from IL-1beta augments antitumor immune responses induced by protein and DNA vaccines.
Hakim I,
Levy S, Levy R.
J Immunol.
1996;
157
(12):
5503-11
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Ligation of TAPA-1 (CD81) or major histocompatibility complex class II in co-cultures of human B and T lymphocytes enhances interleukin-4 synthesis by antigen-specific CD4+ T cells.
Secrist H,
Levy S, DeKruyff RH, Umetsu DT.
Eur J Immunol.
1996;
26
(7):
1435-42
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Novel unconventional binding site in the variable region of immunoglobulins.
Rajagopalan K,
Pavlinkova G, Levy S, Pokkuluri PR, Schiffer M, Haley BE, Kohler H.
Proc Natl Acad Sci U S A.
1996;
93
(12):
6019-24
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Anti-TAPA-1 antibodies induce protein tyrosine phosphorylation that is prevented by increasing intracellular thiol levels.
Schick MR,
Nguyen VQ, Levy S.
J Immunol.
1993;
151
(4):
1918-25
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The TAPA-1 molecule is associated on the surface of B cells with HLA-DR molecules.
Schick MR,
Levy S.
J Immunol.
1993;
151
(8):
4090-7
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Expression of TAPA-1 in preimplantation mouse embryos.
Andria ML,
Barsh GS, Levy S.
Biochem Biophys Res Commun.
1992;
186
(3):
1201-6
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Use of family specific leader region primers for PCR amplification of the human heavy chain variable region gene repertoire.
Campbell MJ,
Zelenetz AD, Levy S, Levy R.
Mol Immunol.
1992;
29
(2):
193-203
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Genomic organization and chromosomal localization of the TAPA-1 gene.
Andria ML,
Hsieh CL, Oren R, Francke U, Levy S.
J Immunol.
1991;
147
(3):
1030-6
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Ig VH gene expression among human follicular lymphomas.
Bahler DW,
Campbell MJ, Hart S, Miller RA, Levy S, Levy R.
Blood.
1991;
78
(6):
1561-8
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Structure and membrane topology of TAPA-1.
Levy S,
Nguyen VQ, Andria ML, Takahashi S.
J Biol Chem.
1991;
266
(22):
14597-602
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Idiotypic variation in a human B lymphoma cell line.
Berinstein N,
Campbell MJ, Lam K, Carswell C, Levy S, Levy R.
J Immunol.
1990;
144
(2):
752-8
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TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins.
Oren R,
Takahashi S, Doss C, Levy R, Levy S.
Mol Cell Biol.
1990;
10
(8):
4007-15
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TAPA-1, the target of an antiproliferative antibody, is associated on the cell surface with the Leu-13 antigen.
Takahashi S,
Doss C, Levy S, Levy R.
J Immunol.
1990;
145
(7):
2207-13
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Activation of an excluded immunoglobulin allele in a human B lymphoma cell line.
Berinstein N,
Levy S, Levy R.
Science.
1989;
244
(4902):
337-9
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Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline V kappa genes to downstream J kappa segment in a murine B cell line.
Levy S,
Campbell MJ, Levy R.
J Exp Med.
1989;
170
(1):
1-13
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Alternative V kappa gene rearrangements in a murine B cell lymphoma. An explantation for idiotypic heterogeneity.
Carroll WL,
Starnes CO, Levy R, Levy S.
J Exp Med.
1988;
168
(5):
1607-20
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Hybridoma fusion cell lines contain an aberrant kappa transcript.
Carroll WL,
Mendel E, Levy S.
Mol Immunol.
1988;
25
(10):
991-5
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Mutational hot spots in Ig V region genes of human follicular lymphomas.
Levy S,
Mendel E, Kon S, Avnur Z, Levy R.
J Exp Med.
1988;
168
(2):
475-89
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A rapid method for cloning and sequencing variable-region genes of expressed immunoglobulins.
Levy S,
Mendel E, Kon S.
Gene.
1987;
54
(2-3):
167-73
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Anti-idiotype antibodies reveal the existence of somatic mutation in human B cell lymphoma.
Levy R,
Levy S, Brown SL, Kon S, Carroll W.
Monogr Allergy.
1987:
22
194-203
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Idiotype vaccination against murine B cell lymphoma. Humoral and cellular responses elicited by tumor-derived immunoglobulin M and its molecular subunits.
Campbell MJ,
Carroll W, Kon S, Thielemans K, Rothbard JB, Levy S, Levy R.
J Immunol.
1987;
139
(8):
2825-33
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Monocistronic transcription is the physiological mechanism of sea urchin embryonic histone gene expression.
Mauron A,
Levy S, Childs G, Kedes L.
Mol Cell Biol.
1981;
1
(7):
661-71
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