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Sam P. Most, M.D., F.A.C.S.

Academic Appointments

Contact Information

  • Clinical Offices
    Otolaryngology - Head & Neck Surgery 801 Welch Rd MC 5739 Stanford, CA 94305
    Tel Work (650) 723-5281 Fax (650) 725-6685
  • Academic Offices
    Personal Information
    Tel (650) 736-3223
    Administrative Contact
    Amanda D'Ambrosio-Akau Patient Care Coordinator/Medical Assistant Tel Work 650 521-6693
    Not for medical emergencies or patient use

Professional Snapshot

Clinical Focus

  • Facial Plastics
  • Otolaryngology
  • Otolaryngology - Head & Neck Surgery (Ear, Nose and Throat)

Professional Education

Board Certification: Otolaryngology, American Board of Otolaryngology (2002)
Fellowship: University of Washington Medical Center, WA USA (2002)
Residency: University of Washington Medical Center, WA USA (2001)
Internship: Yale - New Haven Hospital, CT (1996)
Medical Education: Stanford University School of Medicine, CA (1995)
View All 8

Graduate & Fellowship Program Affiliations

Scientific Focus

Research Interests

Division of Facial Plastic and Reconstructive Surgery-Research Program Summary

Evidence-based medicine in Facial Plastic Surgery
The primary goal of this research program is to develop a higher standard of care for facial plastic surgery patients. The approach to this goal is two-fold. The first involves development of prospective studies that examine the efficacy of new or existing surgical techniques in facial plastic surgery1. One clinical problem we have already begun to examine is nasal obstruction. Functional rhinoplasty techniques have been a mainstay of otolaryngology, and facial plastic surgery in particular, for decades. While many have attempted, with mixed success, to examine nasal function using quantitative measures, few prospective studies of quality of life have been performed. To this end, we have begun to examine prospectively various functional rhinoplasty techniques2, 3.

The second approach to development of a higher standard of care for our patients is the testing of various over-the-counter ‘cosmeceutical’ products. Generally, products that are touted as effective by industry have little or no clinical evidence to back up said claims. Two of these studies have been completed and have resulted in remarkable response from industry as well as the media4, 5. More importantly, these types of studies provide valuable information about product efficacy to physicians and patients alike.

Facial Nerve Recovery after Injury
Facial nerve injury after trauma or extirpative surgery can be devastating to patients. The Division seeks to develop a clinical and basic research program studying facial nerve recovery after such injuries. The basic research program within the Division will use a previously developed animal (mouse) model for facial nerve injury to examine the age-dependence of motor neuron survival in the facial nucleus and its correlation to facial nerve recovery6. Furthermore, the role of apoptotic cell...

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