Justin L. Sonnenburg
Academic Appointments
- Assistant Professor, Microbiology & Immunology
- Member, Bio-X
Professional Snapshot
Professional Education
| BS: | UC Davis, Biochemistry (1996) |
| PhD: | UC San Diego, Biomedical Sciences (2003) |
Postdoctoral Advisees
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Industry Relationships
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| Consulting: | Ganeden Biotech |
Scientific Focus
Research Interests
We are interested in the basic principles that govern interactions within the intestinal microbiota and between the microbiota and the host. To pursue these aims, we colonize germ-free (gnotobiotic) mice with simplified, model microbial communities, apply systems approaches (e.g. functional genomics), and use genetic tools for the host and microbes to gain mechanistic insight into emergent properties of the host-microbial super-organism.
Publications
- Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host. PLoS Biol. 2006; (12): e413
- A hybrid two-component system protein of a prominent human gut symbiont couples glycan sensing in vivo to carbohydrate metabolism. Proc Natl Acad Sci U S A. 2006; (23): 8834-9
- Glycan foraging in vivo by an intestine-adapted bacterial symbiont. Science. 2005; (5717): 1955-9
- Getting a grip on things: how do communities of bacterial symbionts become established in our intestine? Nat Immunol. 2004; (6): 569-73
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