Publications
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Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe.
Xie H,
Mire J, Kong Y, Chang M, Hassounah HA, Thornton CN, Sacchettini JC, Cirillo JD, Rao J.
Nat Chem.
2012;
4
(10):
802-9
-
Self-luminescing BRET-FRET near-infrared dots for in vivo lymph-node mapping and tumour imaging.
Xiong L,
Shuhendler AJ, Rao J.
Nat Commun.
2012:
3
1193
-
Strategies for in vivo imaging of enzyme activity: an overview and recent advances.
Razgulin A,
Ma N, Rao J.
Chem Soc Rev.
2011;
40
(7):
4186-216
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A biocompatible condensation reaction for controlled assembly of nanostructures in living cells
Liang G,
Ren H, Rao J.
Nature Chemistry.
2010;
2
(1):
54-60
-
Self-illuminating quantum dot conjugates for in vivo imaging.
So MK,
Xu C, Loening AM, Gambhir SS, Rao J.
Nat Biotechnol.
2006;
24
(3):
339-43
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Synthesis of ligand-functionalized water-soluble [18F]YF3 nanoparticles for PET imaging.
Xiong L,
Shen B, Behera D, Gambhir SS, Chin FT, Rao J.
Nanoscale.
2013;
5
(8):
3253-6
-
A selenium analogue of firefly D-luciferin with red-shifted bioluminescence emission.
Conley NR,
Dragulescu-Andrasi A, Rao J, Moerner WE.
Angew Chem Int Ed Engl.
2012;
51
(14):
3350-3
-
A strategy to enhance the binding affinity of fluorophore-aptamer pairs for RNA tagging with neomycin conjugation.
Jeon J,
Lee KH, Rao J.
Chem Commun (Camb).
2012;
48
(80):
10034-6
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Controlled self-assembling of gadolinium nanoparticles as smart molecular magnetic resonance imaging contrast agents.
Liang G,
Ronald J, Chen Y, Ye D, Pandit P, Ma ML, Rutt B, Rao J.
Angew Chem Int Ed Engl.
2011;
50
(28):
6283-6
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Controlling intracellular macrocyclization for the imaging of protease activity.
Ye D,
Liang G, Ma ML, Rao J.
Angew Chem Int Ed Engl.
2011;
50
(10):
2275-9
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Immobilizing reporters for molecular imaging of the extracellular microenvironment in living animals.
Xia Z,
Xing Y, Jeon J, Kim YP, Gall J, Dragulescu-Andrasi A, Gambhir SS, Rao J.
ACS Chem Biol.
2011;
6
(10):
1117-26
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MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles.
Daldrup-Link HE,
Golovko D, Ruffell B, Denardo DG, Castaneda R, Ansari C, Rao J, Tikhomirov GA, Wendland MF, Corot C, Coussens LM.
Clin Cancer Res.
2011;
17
(17):
5695-704
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Real-time imaging of Rab5 activity using a prequenched biosensor.
Zhan K,
Xie H, Gall J, Ma M, Griesbeck O, Salehi A, Rao J.
ACS Chem Biol.
2011;
6
(7):
692-9
-
Bioluminescent nanosensors for protease detection based upon gold nanoparticle-luciferase conjugates.
Kim YP,
Daniel WL, Xia Z, Xie H, Mirkin CA, Rao J.
Chem Commun (Camb).
2010;
46
(1):
76-8
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Combining SELEX screening and rational design to develop light-up fluorophore-RNA aptamer pairs for RNA tagging.
Lee J,
Lee KH, Jeon J, Dragulescu-Andrasi A, Xiao F, Rao J.
ACS Chem Biol.
2010;
5
(11):
1065-74
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Facile synthesis, silanization, and biodistribution of biocompatible quantum dots.
Ma N,
Marshall AF, Gambhir SS, Rao J.
Small.
2010;
6
(14):
1520-8
-
Near-infrared light emitting luciferase via biomineralization.
Ma N,
Marshall AF, Rao J.
J Am Chem Soc.
2010;
132
(20):
6884-5
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Superresolution imaging of targeted proteins in fixed and living cells using photoactivatable organic fluorophores.
Lee HL,
Lord SJ, Iwanaga S, Zhan K, Xie H, Williams JC, Wang H, Bowman GR, Goley ED, Shapiro L, Twieg RJ, Rao J, Moerner WE.
J Am Chem Soc.
2010;
132
(43):
15099-101
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A biocompatible condensation reaction for the labeling of terminal cysteine residues on proteins.
Ren H,
Xiao F, Zhan K, Kim YP, Xie H, Xia Z, Rao J.
Angew Chem Int Ed Engl.
2009;
48
(51):
9658-62
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Biosensing and imaging based on bioluminescence resonance energy transfer.
Xia Z,
Rao J.
Curr Opin Biotechnol.
2009;
20
(1):
37-44
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CNOB/ChrR6, a new prodrug enzyme cancer chemotherapy.
Thorne SH,
Barak Y, Liang W, Bachmann MH, Rao J, Contag CH, Matin A.
Mol Cancer Ther.
2009;
8
(2):
333-41
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In vivo bioluminescence imaging of furin activity in breast cancer cells using bioluminogenic substrates.
Dragulescu-Andrasi A,
Liang G, Rao J.
Bioconjug Chem.
2009;
20
(8):
1660-6
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Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice.
Schipper ML,
Iyer G, Koh AL, Cheng Z, Ebenstein Y, Aharoni A, Keren S, Bentolila LA, Li J, Rao J, Chen X, Banin U, Wu AM, Sinclair R, Weiss S, Gambhir SS.
Small.
2009;
5
(1):
126-34
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Semiconductor quantum dots for biosensing and in vivo imaging.
Xing Y,
Xia Z, Rao J.
IEEE Trans Nanobioscience.
2009;
8
(1):
4-12
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HaloTag protein-mediated specific labeling of living cells with quantum dots.
So MK,
Yao H, Rao J.
Biochem Biophys Res Commun.
2008;
374
(3):
419-23
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Imaging target mRNA and siRNA-mediated gene silencing in vivo with ribozyme-based reporters.
So MK,
Gowrishankar G, Hasegawa S, Chung JK, Rao J.
Chembiochem.
2008;
9
(16):
2682-91
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Improved QD-BRET conjugates for detection and imaging.
Xing Y,
So MK, Koh AL, Sinclair R, Rao J.
Biochem Biophys Res Commun.
2008;
372
(3):
388-94
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Quantum dot bioconjugates for in vitro diagnostics & in vivo imaging.
Xing Y,
Rao J.
Cancer Biomark.
2008;
4
(6):
307-19
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Shedding light on tumors using nanoparticles.
Rao J,
ACS Nano.
2008;
2
(10):
1984-6
-
A bioluminogenic substrate for in vivo imaging of beta-lactamase activity.
Yao H,
So MK, Rao J.
Angew Chem Int Ed Engl.
2007;
46
(37):
7031-4
-
Chemical labeling of protein in living cells.
Dragulescu-Andrasi A,
Rao J.
Chembiochem.
2007;
8
(10):
1099-101
-
Fluorescence imaging in vivo: recent advances.
Rao J,
Dragulescu-Andrasi A, Yao H.
Curr Opin Biotechnol.
2007;
18
(1):
17-25
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Quantum dot imaging for embryonic stem cells.
Lin S,
Xie X, Patel MR, Yang YH, Li Z, Cao F, Gheysens O, Zhang Y, Gambhir SS, Rao JH, Wu JC.
BMC Biotechnol.
2007:
7
67
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Quantum dot/bioluminescence resonance energy transfer based highly sensitive detection of proteases.
Yao H,
Zhang Y, Xiao F, Xia Z, Rao J.
Angew Chem Int Ed Engl.
2007;
46
(23):
4346-9
-
Visualizing RNA splicing in vivo.
Gowrishankar G,
Rao J.
Mol Biosyst.
2007;
3
(5):
301-7
-
microPET-based biodistribution of quantum dots in living mice.
Schipper ML,
Cheng Z, Lee SW, Bentolila LA, Iyer G, Rao J, Chen X, Wu AM, Weiss S, Gambhir SS.
J Nucl Med.
2007;
48
(9):
1511-8
-
A self-assembled quantum dot probe for detecting beta-lactamase activity.
Xu C,
Xing B, Rao J.
Biochem Biophys Res Commun.
2006;
344
(3):
931-5
-
Creating self-illuminating quantum dot conjugates.
So MK,
Loening AM, Gambhir SS, Rao J.
Nat Protoc.
2006;
1
(3):
1160-4
-
Detection of mRNA in mammalian cells with a split ribozyme reporter.
Hasegawa S,
Gowrishankar G, Rao J.
Chembiochem.
2006;
7
(6):
925-8
-
HaloTag protein-mediated site-specific conjugation of bioluminescent proteins to quantum dots.
Zhang Y,
So MK, Loening AM, Yao H, Gambhir SS, Rao J.
Angew Chem Int Ed Engl.
2006;
45
(30):
4936-40
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How molecular imaging is speeding up antiangiogenic drug development.
Cai W,
Rao J, Gambhir SS, Chen X.
Mol Cancer Ther.
2006;
5
(11):
2624-33
-
Modulating the splicing activity of Tetrahymena ribozyme via RNA self-assembly.
Hasegawa S,
Rao J.
FEBS Lett.
2006;
580
(6):
1592-6
-
Protease-modulated cellular uptake of quantum dots.
Zhang Y,
So MK, Rao J.
Nano Lett.
2006;
6
(9):
1988-92
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Cell-permeable near-infrared fluorogenic substrates for imaging beta-lactamase activity.
Xing B,
Khanamiryan A, Rao J.
J Am Chem Soc.
2005;
127
(12):
4158-9
-
Single-cell detection of trans-splicing ribozyme in vivo activity.
Hasegawa S,
Choi JW, Rao J.
J Am Chem Soc.
2004;
126
(23):
7158-9
-
Imaging Tetrahymena ribozyme splicing activity in single live mammalian cells.
Hasegawa S,
Jackson WC, Tsien RY, Rao J.
Proc Natl Acad Sci U S A.
2003;
100
(25):
14892-6
-
Novel fluorogenic substrates for imaging beta-lactamase gene expression.
Gao W,
Xing B, Tsien RY, Rao J.
J Am Chem Soc.
2003;
125
(37):
11146-7
-
Binding of a dimeric derivative of vancomycin to L-Lys-D-Ala-D-lactate in solution and at a surface.
Rao J,
Yan L, Lahiri J, Whitesides GM, Weis RM, Warren HS.
Chem Biol.
1999;
6
(6):
353-9
-
A trivalent system from vancomycin.D-ala-D-Ala with higher affinity than avidin.biotin.
Rao J,
Lahiri J, Isaacs L, Weis RM, Whitesides GM.
Science.
1998;
280
(5364):
708-11
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Affinity capillary electrophoresis: a physical-organic tool for studying interactions in biomolecular recognition.
Colton IJ,
Carbeck JD, Rao J, Whitesides GM.
Electrophoresis.
1998;
19
(3):
367-82
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