Frederick T. Chin, Ph.D.

Publication Details

• No-carrier-added [18F]fluoroarenes from the radiofluorination of diaryl sulfoxides.

  Chun JH, Morse CL, Chin FT, Pike VW. Chem Commun (Camb). 2013; 49 (21): 2151-3

  No-carrier-added [(18)F]fluoroarenes were synthesized through the radiofluorination of diaryl sulfoxides with [(18)F]fluoride ion. Diaryl sulfoxides bearing a para electron-withdrawing substituent readily gave the corresponding 4-[(18)F]fluoroarenes in high RCYs. This process broadens the scope for preparing novel (18)F-labeling synthons and PET radiotracers.

  PubMedID: 23388835