Sharon Pitteri
Publication Details
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Microparticles from ovarian carcinomas are shed into ascites and promote cell migration.
Int J Gynecol Cancer. 2012; (4): 546-52
Microparticles are cellular-derived vesicles (0.5-1.0 μm) composed of cell membrane components, which are actively shed from the surface of various cells, including epithelial cells. We compared microparticles in ascites between women with ovarian carcinoma and women with benign ovarian pathology, and isolated tumor-derived (epithelial cell adhesion molecule [EpCAM]-positive) microparticles for functional analysis and proteomics.
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