Heike Daldrup-Link

Publication Details

• Labeling human embryonic stem-cell-derived cardiomyocytes for tracking with MR imaging.

  Castaneda RT, Boddington S, Henning TD, Wendland M, Mandrussow L, Liu S, Daldrup-Link H. Pediatr Radiol. 2011; 41 (11): 1384-92

  Human embryonic stem cells (hESC) can generate cardiomyocytes (CM), which offer promising treatments for cardiomyopathies in children. However, challenges for clinical translation result from loss of transplanted cell from target sites and high cell death. An imaging technique that noninvasively and repetitively monitors transplanted hESC-CM could guide improvements in transplantation techniques and advance therapies.

  PubMedID: 21594541