Publication Details

Activators of protein kinase C selectively mediate cellular cytotoxicity to hypoxic cells and not aerobic cells.

Koong AC, Chen EY, Kim CY, Giaccia AJ. Int J Radiat Oncol Biol Phys. 1994; 29 (2): 259-65

By understanding the signal transduction pathways through which a cell responds to changes in environmental oxygen levels, we may be able to therapeutically exploit this response by manipulating these pathways.

PubMedID: 8195017